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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
high decrease » slight decrease (Expand Search), high degree (Expand Search), high disease (Expand Search)
increase » increased (Expand Search)
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19001
Image 1_Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies.pdf
Published 2025“…</p>Results<p>Thirty studies involving 559 animals were identified for analysis. TMP treatment significantly decreased Scr (SMD = 2.35, 95% CI: −2.97 to −1.72, P < 0.05), BUN (SMD = −2.4, 95% CI: −3.01 to −1.79, P < 0.05). …”
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19002
Supplementary file 3_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…</p>Results<p>Our analysis revealed that the proportion of CCR7<sup>+</sup> Tregs decreased as the disease advanced, while the cell proportion of HLA_DR<sup>+</sup> regs escalated with the severity of the disease. …”
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19003
Video 1_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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19004
Image 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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19005
Characteristics comparison of related literature.
Published 2025“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”
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19006
Table 1_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.doc
Published 2025“…No significant differences were observed in other indicators.…”
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19007
Supplementary Material for: Non-Prescribed Use of Opioid Agonist Medications and Associations with Non-Fatal Overdoses: A Repeated Cross-Sectional Study Across a Decade of Reduced...
Published 2025“…Multinomial regression analyses showed no significant association between non-prescribed OAT use and increased risk of non-fatal overdoses. …”
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19008
Data Sheet 1_Probiotic administration correlated with reduced diarrheal incidence and improved gut microbiota diversity in young goats.pdf
Published 2025“…The predominant phyla identified were Pseudomonadota, Bacteroidetes, and Bacillota.Increased levels of Xylanibacter, UCG-055, Bacteroides, and Escherichia-Shigella were noted in healthy treated kids, while Prevotellaceae UG_001 and Proteus decreased.</p>Discussion<p>The findings highlight significant gut microbiota differences between healthy and diarrheal kids, suggesting that modifications in gut microbiota composition could alleviate diarrhea, contributing to preventive and therapeutic strategies for this condition.…”
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19009
Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…</p>Results<p>Our analysis revealed that the proportion of CCR7<sup>+</sup> Tregs decreased as the disease advanced, while the cell proportion of HLA_DR<sup>+</sup> regs escalated with the severity of the disease. …”
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19010
Table 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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19011
Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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19012
Neurofilament light chain as a biomarker for hereditary ATTR amyloidosis − correlation between neurofilament light chain and nerve conduction study
Published 2024“…NfL levels significantly decreased with patisiran, although no significant changes were observed in CMAP and SNAP.…”
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19013
Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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19014
Enamel matrix derivative in the treatment of tooth replantation: from a biological basis to clinical application
Published 2024“…Although the pooled outcomes suggested increased incidence of surface resorption (RR=1.19, <i>P</i>=0.730) and decreased risk of inflammation resorption (RR=0.68, <i>P</i>=0.560) among replanted teeth with resorption in the EMD-treated group, neither difference was statistically significant.…”
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19015
DataSheet3_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf
Published 2024“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”
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19016
Image 2_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”
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19017
Table 1_Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.docx
Published 2024“…</p>Results<p>CQAB supplementation demonstrated a significant (P < 0.05) improvement in Total Nasal Symptom Score (TNSS) compared to placebo and CGM. …”
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19018
Table 4_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.xlsx
Published 2025“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”
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19019
Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”
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19020
Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf
Published 2025“…<p>Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor immunization responses afflict patients. …”