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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
high decrease » slight decrease (Expand Search), high degree (Expand Search), high disease (Expand Search)
increase » increased (Expand Search)
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19501
Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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19502
LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p
Published 2025“…<p>Cerebral ischemia-reperfusion (CI/R) injury is a significant hurdle in ischemic stroke treatment. Substantial evidence indicates that long non-coding RNAs (lncRNAs) are implicated in CI/R injury. …”
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19503
Data Sheet 2_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip
Published 2025“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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19504
DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx
Published 2024“…Although the population of F4/80<sup>+</sup>CD11b<sup>+</sup> intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1<sup>+</sup>MerTK<sup>+</sup>) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”
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19505
Data Sheet 1_Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss.pdf
Published 2025“…We also observed decreased percentages of IFN-γ<sup>+</sup> pNK cells (49% vs 25.2%, p=0.027) after exercise.…”
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19506
Image 4_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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19507
Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf
Published 2025“…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …”
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19508
Data Sheet 1_Integrated physiological, transcriptomic, and metabolomic analyses of Chrysanthemum ‘Boju’ under excessive indole-3-acetic acid stress.pdf
Published 2025“…Exogenous IAA treatment also led to a significant reduction in endogenous hormone levels, including gibberellins (GA<sub>3</sub> and GA<sub>4</sub>), abscisic acid (ABA), and IAA, with decreases of 93%, 45%, 99%, and 99%, respectively.Transcriptomic and metabolomic analyses identified 263 differentially expressed metabolites and 144 differentially expressed genes.…”
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19509
Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx
Published 2025“…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data on this issue are currently lacking. …”
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19510
Table 1_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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19511
Image 3_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.tif
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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19512
<i>Tmprss6</i> modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway
Published 2025“…<p>Radiation-induced liver injury (RILI) poses a significant challenge in abdomino-pelvic tumor radiotherapy, adversely impacting normal liver tissues. …”
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19513
Table 1_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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19514
Table 1_Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.xlsx
Published 2025“…Median survival durations decreased progressively: 716 days (mild), 362 days (moderate), and 106 days (severe). …”
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19515
Data Sheet 1_Comparison of intravascular imaging, physiological assessment and angiography for coronary revascularization in acute coronary syndrome: a systematic review and networ...
Published 2025“…The research unveiled no statistically significant differences between FFR-guided culprit-only PCIs and culprit-only PCIs or angiography-guided CR.…”
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19516
<b><i>N</i></b><sup><strong>6</strong></sup><b>-Methyladenosine demethylase FTO controls</b><b>macrophage homeostasis in diabetic vasculopathy</b>
Published 2024“…<p dir="ltr"><b>Abstract</b></p><p dir="ltr">Diabetic vasculopathy, encompassing complications such as diabetic retinopathy, represents a significant source of morbidity, with inflammation playing a pivotal role in the progression of these complications. …”
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19517
Table 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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19518
Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx
Published 2025“…No significant increase in adverse drug events (ADEs) was observed (RR = 1.32, 95% CI 0.58–2.96). …”
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19519
Table 6_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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19520
Data Sheet 1_Artificial clicks (Porpoise ALert) affect acoustic monitoring of harbour porpoises and their echolocation behaviour.pdf
Published 2025“…</p>Discussion<p>The consequences for compromised monitoring are significant, particularly in regions with low harbour porpoise densities, where artificial signals may influence the interpretation of diurnal and seasonal aspects of natural harbour porpoise behaviour, leading to misinterpretations. …”