Table 3_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.docx by Haddad A. El Rabey (22248019)

“…The induced hypercholesterolemia significantly raised liver function enzymes, lipid peroxidation (14.9 ± 0.11 mg/dL), total cholesterol (273.3 ± 1.1 mg/dL), triglycerides (223.0 ± 4.1 mg/dL), low-density lipoproteins (204.7 ± 0.9 mg/dL), very low-density lipoproteins (44.6 ± 0.8 mg/dL), troponin, creatine kinase (CK), and adrenaline while decreased antioxidant enzymes, high-density lipoprotein (HDL), and vitamin D (11.1 ± 0.5 ng/mL). …”

Supplementary Materials - Figure by Shaojie Zhang (20807333)

“…<p dir="ltr">Exposure to hypobaric hypoxia during rapid ascent to high altitudes significantly impacts intestinal barrier function. Goblet cells, as one of the primary cell types in the intestinal mucosa, play a crucial role in maintaining this barrier. …”

Image 1_Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies.pdf by Zhongmei Fu (11869694)

“…</p>Results<p>Thirty studies involving 559 animals were identified for analysis. TMP treatment significantly decreased Scr (SMD = 2.35, 95% CI: −2.97 to −1.72, P < 0.05), BUN (SMD = −2.4, 95% CI: −3.01 to −1.79, P < 0.05). …”

Supplementary file 3_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

“…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …”

Video 1_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Image 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Type level landscape index changes in 1990-2020. by Chao Ma (207385)

“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”

Characteristics comparison of related literature. by Bin Zhao (276445)

“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”

Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Data Sheet 1_Probiotic administration correlated with reduced diarrheal incidence and improved gut microbiota diversity in young goats.pdf by Mohamed Osman Abdalrahem Essa (21562583)

“…The predominant phyla identified were Pseudomonadota, Bacteroidetes, and Bacillota.Increased levels of Xylanibacter, UCG-055, Bacteroides, and Escherichia-Shigella were noted in healthy treated kids, while Prevotellaceae UG_001 and Proteus decreased.</p>Discussion<p>The findings highlight significant gut microbiota differences between healthy and diarrheal kids, suggesting that modifications in gut microbiota composition could alleviate diarrhea, contributing to preventive and therapeutic strategies for this condition.…”

Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

“…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …”

Table 1_Biliary microbiota in disease-free, obstructive and post-drainage biliary tracts.docx by Guiyuan Zhang (13994877)

“…Furthermore, the increased incidence of bacterial infections following biliary drainage poses a significant clinical concern; however, the relationship between biliary drainage and biliary flora remains poorly understood. …”

Data Sheet 1_High humidity environment increases FBG by impairing the intestinal barrier.zip by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Table 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx by Man Zhao (314232)

“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”

Image 3_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... by Yangtian Jiao (21725018)

“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”

Data Sheet 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Table 2_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx by Yali Han (4676677)

“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”