Data Sheet 3_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease... by Shuyu Zheng (5570231)

“…</p>Conclusion<p>These results indicate that SM preparations could considerably improve renal and vascular endothelial function while simultaneously decreasing harmful inflammatory markers in patients with DKD, which allow it serve as a safe and effective therapeutic option.…”

Data Sheet 2_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease... by Shuyu Zheng (5570231)

“…</p>Conclusion<p>These results indicate that SM preparations could considerably improve renal and vascular endothelial function while simultaneously decreasing harmful inflammatory markers in patients with DKD, which allow it serve as a safe and effective therapeutic option.…”

Image 3_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca... by Huihui Zhu (4483621)

“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”

Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca... by Huihui Zhu (4483621)

“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”

DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Effects of vidarabine, V2E, V3E and V5E on AC activity in the heart of WT and AC5KO mice. by Kenji Suita (750993)

“…<p>(A) Vidarabine (Vida), V2E, V3E and V5E similarly and significantly decreased ISO (50 µmol/L)-stimulated AC activity in the WT heart in a dose-dependent manner. …”

Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of... by Xiaoqing Xia (14607269)

“…</p>Results<p>The number of IHD deaths and DALYs resulting from non-optimal temperature experienced a rise of 71.6% and 60.6%, respectively. And it showed regional imbalances: in the region with low-middle socio-demographic index (SDI), it was increased [EAPC for ASMR: 0.39% (95% CI: 0.2%, 0.58%), EAPC for ASDR: 0.33% (95% CI: 0.15%, 0.52%)], while decreased in the high SDI region, [EAPC for ASMR: −3.44% (95%CI: −3.58%, −3.3%), EAPC for ASDR: −3.18% (95%CI: −3.32%, −3.03%)]. …”

Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx by Hailiang Li (740080)

“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”

Table 1_Exogenous jasmonic acid and salicylic acid enhance selenium uptake and mitigate cadmium accumulation in pak choi (Brassica chinensis L.) grown in selenium-rich, high-cadmiu... by Jin-Ping Chen (6003755)

“…Hormone treatments significantly increased shoot Se content by 33.7%-62.3% compared to the control, with the highest level Se accumulation observed under combined application of 50 μmol·L^-1 JA and 50 μmol·L^-1 SA. …”

Supplementary file 1_Global, regional, and national total burden related to hepatitis B and attributable risk factors in adults aged 65 years and older from 1990 to 2021 and projec... by Linying Gao (4379200)

“…</p>Results<p>From 1990 to 2021, the global age-standardized incidence rate (ASIR) of total burden related to hepatitis B among older adults aged ≥65 years declined from 710.53 to 591.79 per 100,000 population (AAPC −0.57%), and age-standardized DALYs rate (ASDR) declined from 927.65 to 605.93 per 100,000 population (AAPC -1.39%). ASIR and ASPR both showed significant decreasing trends in males and females, with persistently higher rates observed among males across all study years. …”

Overview of BDHS data. by Keith Beam (20700854)

“…<div><p>Oral zinc is a proven effective treatment for diarrheal illness, and long-term monitoring is key to evaluating the success of efforts to scale up zinc treatment. …”

Framework synthesis of zinc scale-up programs. by Keith Beam (20700854)

“…<div><p>Oral zinc is a proven effective treatment for diarrheal illness, and long-term monitoring is key to evaluating the success of efforts to scale up zinc treatment. …”

Evaluation of disparities in zinc coverage. by Keith Beam (20700854)

“…<div><p>Oral zinc is a proven effective treatment for diarrheal illness, and long-term monitoring is key to evaluating the success of efforts to scale up zinc treatment. …”

ORS and zinc coverage, by country, DHS data only. by Keith Beam (20700854)

“…<div><p>Oral zinc is a proven effective treatment for diarrheal illness, and long-term monitoring is key to evaluating the success of efforts to scale up zinc treatment. …”

Overall program sustainability assessment results. by Amanda Marr Chung (21696743)

Image 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Background<p>Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). …”

Table 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Background<p>Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”

<b>Soil C mineralization and C-Fe coupling: a trade-off between Fenton reaction and </b><b>microbial activity</b><b> under straw mulching in banana orchards</b> by Lingbo Dong (19185916)

“…Although straw mulching negatively impacted soil C mineralization via reducing ROS, it also promoted soil C mineralization through enhancing microbial activity and decreasing Fe-OC, resulting in significantly increased soil C mineralization. …”

Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p... by Guoliang Gao (2910503)

“…The incidence in females was marginally greater than that in males, yet there were comparable decreases in deaths and DALYs for both sexes. There was a notable increase in prevalence in regions with high SDIs, whereas areas with low SDIs experienced greater disease burdens. …”