FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…The grids below the bar graph show reported RBP Functions (red boxes), Intracellular Localization (green boxes), and FLEXI Interactions (blue boxes). RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Single-cell RNA-seq dataset of innate lymphoid cells by Sijie Chen (12510043)

“…Our research, along with others’, indicates a high proportion of LTi cells in the fetal ILC pool, which significantly decreases after birth. …”

Effect of CBZ pretreatment on HSR-induced histological damage in the lungs of rats with acute lung injury. by Yaqiang Li (7423778)

“…However, these histopathological changes were significantly ameliorated after treatment with CBZ. DMSO had no influence on histological damage, while the CBZ/CQ/HSR group showed a severe damage compared with the CBZ/HSR group. …”

Table 2_Effect of low salicylate diet and blood salicylate level on the symptom control of chronic spontaneous urticaria.docx by Sercan Guloglu (22801190)

“…The CU-Q2oL scores significantly decreased from 33.7 to 20.7 (p < 0.001) and the UAS4 significantly decreased from 14 to 8 (p < 0.001) after low salicylate diet when compared to baseline (low scores mean less complaints). …”

original data.xlsx by Peng Shen (20145351)

“…<b>Research Results</b>: The results showed that the levels of inflammatory factors significantly decreased in the blood purification treatment group after treatment, with a notable reduction in hospitalization and ICU stay duration compared to the conventional treatment group. …”

<b>The Bacterial OMP Amyloids Modulate</b><b> </b><b>α</b><b>-Synuclein and Amyloid-</b><b>β</b><b> </b><b>Aggregation</b> by Maksim Sulatsky (21562922)

“…In contrast, amyloid-β fibrils showed more extensive structural changes, with modifications to both the "fuzzy coat" and β-sheet core, accompanied by decreased clustering tendency and significantly reduced toxicity for mammalian neuroblastoma and epithelial adenocarcinoma cell lines. …”

GABA and glutamate are required for light avoidance. by Kenichi Nakayama (2354653)

“…One-way ANOVA Dunnett’s multiple comparison tests, compared with wild type. n.s = not significant, *<i>P</i> < 0.05, ****<i>P</i> < 0.0001.…”

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy by Tanvi Chokshi (12970453)

“…Aqueous RBP3 decreased from a median of 2.1nM [IQR 0.8-3.4nM] in eyes with no DR to 1.5nM [0.8-3.8nM] in eyes with mild-moderate NPDR (P=0.047). …”

This is raw data of IL-10 real-time PCR. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

This is raw data of Gal-9 real-time PCR. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

This is raw data of IL-10 ELISA. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

This is raw data of NF-κB real-time PCR. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

This is raw data of β-catenin real-time PCR. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

Details of the primers applied in real-time PCR. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

This is raw data of viability data. by Farzad Nasri (8941850)

“…<i>IL-1β</i> gene expression was reduced following either IFN-β or Vit D treatment, while <i>IL-10</i> gene expression underwent a gentl increase following treatment with IFN-β, which was in contrast to Vit D treatment. …”

Figure 5 from Elraglusib Induces Cytotoxicity via Direct Microtubule Destabilization Independently of GSK3 Inhibition by Josh T. Coats (20321355)

“…Fold change calculated vs. control, error bars represent SEM, and statistical significance was determined using one-way ANOVA, with <i>P</i> ≤ 0.05. ns, not significant; *, <i>P</i> < 0.05; ****, <i>P</i> < 0.0001.…”

Functional assays of neurotoxicity testing of α-terpineol in Wistar rats by Sneha Suma Hegde (19856407)

“…This study in Wistar rats aimed to investigate the impacts of α- terpineol, a natural compound, on neurotoxicity. Forty-eight healthy Wistar rats, including 24 males and 24 females, were obtained, acclimated for 7 days, and housed in controlled environmental conditions with a balanced diet and <i>ad libitum</i> access to water. …”

Supplementary Material for: Effect of endobronchial valve treatment on skeletal muscles, fatigue, and sleep in severe emphysema patients by figshare admin karger (2628495)

“…Intercostal thickening fraction did not change following treatment. Fatigue decreased significantly, reducing severe fatigue prevalence from 70% to 25%. …”

Supplementary Material for: International Variation and Trends of Intraventricular Hemorrhage in Very Preterm Infants by figshare admin karger (2628495)

“…Japan and Canada demonstrated significant decreases in each GA group while Spain demonstrated significant decreases in each GA group except for 22-23 weeks’ gestation. …”

Efficacy of Low-Dose Naltrexone in Treating Patients with Fibromyalgia: systematic Review and Meta-Analysis by Abiodun Ologunowa (21343002)

“…In the LDN group, the Standardized Mean Difference (SMD) for pain decreased by 1.03 (95% confidence interval (CI): −1.25, −0.80; I² = 25%), and fibromyalgia symptom severity decreased by 1.02 (95% CI: −1.35, −0.69; I² = 52%) post-LDN treatment compared to the baseline. …”