بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
i decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
i decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
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4441
Data Sheet 1_Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss.docx
منشور في 2025"…We used the AD mouse model AβPPswe/PS1A246E to show that neuronal S100B levels are significantly higher in 10-month-old animals, and cellular assays to demonstrate that Aβ oligomers significantly increase S100B expression in SH-SY5Y cells, but not monomeric or fibrillar Aβ. …"
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4442
Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx
منشور في 2025"…We found that the upregulated hsa-miR-33a-5p repressed IGFBP5 translation by forming a silencing complex with Argonaute protein 2 (AGO2) in a real-ambient PM exposure system, which further led to the suppression of the ERK1/2-SOD2 signaling pathway and increased levels of ROS.…"
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4443
Data Sheet 1_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv
منشور في 2025"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"
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4444
Image 1_A comprehensive analysis of vitamin a deficiency burden and trends: insights from the global burden of disease study 2021 and future predictions to 2050.pdf
منشور في 2025"…Background<p>Vitamin A deficiency (VAD) continues to pose a significant public health challenge, particularly in low socio-demographic index (SDI) regions, contributing to increased infections, blindness, and child mortality. …"
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4445
Differentially used transcripts (DUT) for T1R and LEP groups suggest dysregulation of inflammatory circuitry in T1R.
منشور في 2024"…Rows were sorted by decreasing values of PΔ<sub>T1R</sub>, then re-arranged in three blocks: i) positive PΔ for both groups, ii) opposite PΔ and iii) negative PΔ for both groups. …"
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4446
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4447
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4448
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4449
The <i>ENT2</i> knockout effects on CRC proliferation and survival.
منشور في 2025"…(F) Cell proliferation of DLD1/KO cells. Data are presented as means ± SD and expressed as % relative to control cells. * indicates a significant difference between NTC vs. …"
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4450
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4451
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4452
Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf
منشور في 2025"…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …"
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4453
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4454
Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction
منشور في 2025"…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …"
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4455
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4456
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4457
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4458
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4459
Table 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.xlsx
منشور في 2025"…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"
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4460
Image 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.tif
منشور في 2025"…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"