Supplementary Material for: Albumin and platelet loss during the application of CytoSorb® in critically ill patients: a post-hoc analysis of the Cyto-SOLVE trial by Brozat C.I. (20130933)

SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation. by Dilara Koc (22431017)

“…Representative blots of 4 independent experiments are shown. Syntaxin-1A intensity normalized to SNAP-25 levels in each IP blot was quantified. ns: non-significant; *: P ≤ 0.05; **: P ≤ 0.01; ***: P ≤ 0.001. …”

(Related to Fig 1): LPN promote evening sleep via AstC under high temperature condition. by Xin Yuan (174619)

“…(C, D) LPN activation via the thermogenetic dTrpA1 channel (<i>LPN-spGal4>Uas-dTrpA1</i>) significantly decreases daily locomotion compared to baseline (black bar). …”

Data Sheet 1_Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity.docx by Krishma Tailor (13730582)

“…Furthermore, we found that subcutaneous CV1574-1 showed significantly reduced hypoglycemic effect compared to injection of IGF-1 itself. …”

Analysis of biases in amplicon coverage across samples sequenced with diverse Ampliseq-based protocols (DDD/IDI/III – corresponds to variations of PCR mix1 (I/D), ligase/buffer (I/... by P.A. Shatalov (21485215)

“…<p><b>(A)</b> – heatmap of amplicon coverage (% of average coverage) across samples demonstrates significant variation in per-sample set of dropped out (10% of average sample coverage) amplicons depending on <b>i)</b> PCR mix 2 used <b>ii)</b> Digest Mix used. …”

Percentage of different <i><i>d</i></i>_max/<i><i>d</i></i>_min. by Yanxu Liang (22227024)

“…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…”

Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)₂D levels compared to naïve mice. 1,25(OH)₂D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”

Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)₂D levels compared to naïve mice. 1,25(OH)₂D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”

Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx by Johnny Amer (495285)

“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)₂D levels compared to naïve mice. 1,25(OH)₂D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”

Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg by Johnny Amer (495285)

“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)₂D levels compared to naïve mice. 1,25(OH)₂D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”

Metabolic characteristics of T2DM mice. by Yan Zhu (112437)

“…<div><p>Background</p><p>Type 2 diabetes mellitus (T2DM) is associated with cognitive dysfunction, which significantly impacts the quality of life. Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has shown potential neuroprotective effects. …”

Schematic diagram of the study design. by Yan Zhu (112437)

“…<div><p>Background</p><p>Type 2 diabetes mellitus (T2DM) is associated with cognitive dysfunction, which significantly impacts the quality of life. Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has shown potential neuroprotective effects. …”

The relationship between HBV antigens deposition in kidneys and renal prognosis in IgA nephropathy patients infected with HBV by Yun Guo (135103)

“…The primary outcome was a composite of 30% decrease in eGFR from the baseline, kidney failure and all-cause mortality. …”

Dynamic Regulation of Proton and Water Transport through an Acylhydrazone-Based Photoresponsive Channel by Paras Wanjari (22259362)

“…A similar trend was observed in water transport, where the single-channel permeability of <b>1a</b> increased from 6.5 × 10⁶ to 3.5 × 10⁷ water molecules/s/channel upon switching from the <i>E</i> to <i>Z</i> isomers, then decreased to 1.8 × 10⁷ after reverting to the <i>E</i> conformer. …”

Flow chart of the study design. by Ramita Gupta (21512558)

“…VJH improved significantly (p < 0.001) among defenders (Δ = 3.44 cm, 95% CI: 1.76 to 5.12, d = 1.06), while power improvements were most notable in defenders (Δ<b> =</b> 43.44W, 95% CI: 28.62 to 58.26, d = 1.00). …”

Information of core targets. by Guobing Wang (288885)

“…The migration assay showed that the incubation of the medium with a mixture of 10 mg/mL each or 72h of 5 ml/mL each significantly inhibited the migration of Hela cells (P <0.001). …”

Composition of Scutellaria Barbata. by Guobing Wang (288885)

“…The migration assay showed that the incubation of the medium with a mixture of 10 mg/mL each or 72h of 5 ml/mL each significantly inhibited the migration of Hela cells (P <0.001). …”

GO function enrichment analysis. by Guobing Wang (288885)

“…The migration assay showed that the incubation of the medium with a mixture of 10 mg/mL each or 72h of 5 ml/mL each significantly inhibited the migration of Hela cells (P <0.001). …”

KEGG functional enrichment analysis. by Guobing Wang (288885)

“…The migration assay showed that the incubation of the medium with a mixture of 10 mg/mL each or 72h of 5 ml/mL each significantly inhibited the migration of Hela cells (P <0.001). …”

Effect of dilution factor and replicate number on the reproducibility of αSyn^D seed concentration estimates in PD (A-D) and DLB (E-H) brain homogenates by ED RT-QuIC ass... by Ankit Srivastava (742990)