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12541
Table 2_Gut metagenomic features of frailty.xlsx
Published 2024“…Taxonomically, we observed a significant inverse correlation between Firmicutes abundance and frailty. …”
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12542
Hippocampal volume changes along the rostrocaudal axis in the COUP-TFI mutant mice.
Published 2025“…The size of the domain with dense YFP<sup>+</sup> cells in the caudal hippocampus was decreased in the COUP-TFI cKO (<i>COUP-TFI</i><sup>f/f</sup>; <i><i>Emx1</i></i>-Cre) and increased in the COUP-TFI cTG (<i>COUP-TFI</i><sup>TG/O</sup>; <i><i>Emx1</i></i>-Cre). …”
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12543
Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
Published 2025“…The effects of the surgical and corneal topographic parameters on EOZ were explored.</p> <p>A significantly higher postoperative spherical equivalent was found in group B than in group A (<i>p</i> = 0.002). …”
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12544
Supporting information Abou-Kandil et al.
Published 2024“…Deletion of <i>rtaA</i> did not significantly change the ergosterol content of <i>A. fumigatus</i>, but decreased fluorescence intensity of the sterol-binding stain filipin. …”
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12545
The efficacy of metformin in counteracting olanzapine-induced hyperprolactinemia: an open-label prospective study
Published 2025“…</p> <p>After eight weeks of metformin intervention, prolactin levels significantly decreased from 39.7 ± 20.0 ng/mL at baseline to 35.7 ± 15.7 ng/mL (<i>p</i> = 0.005) with a moderate effect size (Cohen’s <i>d</i> = 0.545). …”
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12546
Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma
Published 2025“…In the lung, the combined treatment led to a significant lower number of metastases compared with trabectedin (*, <i>P</i> < 0.05), or with NVP-BEZ235 (**, <i>P</i> < 0.01) as single agents. …”
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12547
Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice
Published 2025“…Ethanol exposure decreased instantaneous frequency evoked by 250–400 pA current injection in fast-spiking GABAergic interneurons only in female mice (250: <i>p</i> = .019, g = −1.08; 300–450: <i>p</i> = .038, g = −1.06 to- 1.18) but did not significantly affect spontaneous inhibitory postsynaptic currents (sIPSCs) evoked by interneuronal GABA release onto pyramidal neurons.…”
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12548
Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease
Published 2025“…</p> <p>We included 25 PD patients with a mean age of 65.7 ± 9.0 y (F/M = 9/16). The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”
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12549
Low-speed Rear-end Collisions: Kinematic and Clinical Responses (Video, MRI findings, EMG/NCS results)
Published 2025“…Pain questionnaires were administered immediately after the test and one week later.</i></p><p dir="ltr"><b><i>Results</i></b><i>: Impact velocity, offset percentage, and collision type significantly influenced acceleration forces and NIC values, with passenger vehicle collisions generating higher forces than bumper car collisions. …”
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12550
Effects and Potential Risks of Chiral Penflufen on Pickled Cowpea: Combined Microbiome and Metabolomics
Published 2025“…<i>S</i>-Penflufen reduced alcohols and increased esters more significantly, and altered a higher number of volatile organic compounds (VOCs) and chiral amino acids than <i>R</i>-penflufen, showing a greater risk to food flavor and nutritional quality.…”
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12551
Neurochemical identity of dFB<sup>23E10</sup>Ո<sup>84C10</sup> neurons.
Published 2025“…<b>(D)</b> Representative confocal stack of a female <i>84C10-AD; Gad1-DBD>UAS-mCD8GFP</i>. …”
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12552
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Yet, OSBP is an attractive antiviral target, as it is hijacked by many positive-strand RNA viruses. Remarkably, (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B significantly inhibited Zika virus replication in human cells, highlighting its potential as a lead compound for antiviral drug development.…”
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12553
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Yet, OSBP is an attractive antiviral target, as it is hijacked by many positive-strand RNA viruses. Remarkably, (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B significantly inhibited Zika virus replication in human cells, highlighting its potential as a lead compound for antiviral drug development.…”
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12554
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Yet, OSBP is an attractive antiviral target, as it is hijacked by many positive-strand RNA viruses. Remarkably, (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B significantly inhibited Zika virus replication in human cells, highlighting its potential as a lead compound for antiviral drug development.…”
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12555
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
Published 2024“…Yet, OSBP is an attractive antiviral target, as it is hijacked by many positive-strand RNA viruses. Remarkably, (<i>R</i>,<i>R</i>,<i>R</i>)-macarangin B significantly inhibited Zika virus replication in human cells, highlighting its potential as a lead compound for antiviral drug development.…”
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12556
Alcohol perceptions and driving decisions among adolescents: Exploring the role of peer and parental influences in Virginia
Published 2025“…Though parent distracted driving positively influenced adolescent driving behavior, this effect was not statistically significant (coefficient = 0.008, <i>P</i> = .320).</p> <p>The findings indicate a significant reduction in risky behaviors such as drinking and driving and an increase in seat belt use among adolescents. …”
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12557
SEAwise Report on the impacts of fisheries on stocks and landings under SEAwise EBFM
Published 2025“…<i>Spatio-temporal closures scenarios</i> in the Bay of Biscay where on the one hand a spatio-temporal closure of one month to protect Dolphins was simulated and on the other different MPA-s with different extension to protect benthic communities were tested.…”
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12558
Supplementary Material for: Real-life nationwide outcomes of bronchoscopic lung volume reduction with endobronchial valves in severe COPD
Published 2024“…Results: Following BLVR, a significant increase in FEV1, similar to the improvements reported in randomized controlled trials was observed. …”
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12559
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12560
GnRH antagonist impairs the process of embryo implantation by inhibiting motility of endometrial stromal cells through reducing c-kit expression
Published 2024“…</i> 56.1%, <i>p</i> < .001) in the GnRH-ant group were significantly decreased. …”