Table 2_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx حسب Hongyu Zhou (352858)

"…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …"

Image 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf حسب Guanfei Zhao (3815596)

"…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …"

Data Sheet 1_Effects of plant extracts on patients with heart failure: a network meta-analysis of randomized controlled trials.pdf حسب Jieyin Deng (22563188)

"…Shenfu extract exhibited superior efficacy in decreasing B-type natriuretic peptide (BNP) values (SUCRA: 68.2%) and enhancing the quality of life (QL) (SUCRA: 77.0%). …"

Table 10_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls حسب Meizhi Liu (21898892)

"…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …"

Table 14_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx حسب Yanyao Lu (22163632)

"…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …"

General.Data. Proyect Glycerol.csv حسب Rodrigo Yañez (20679089)

"…Additionally, although BT slightly decreased (<i>p</i> = 0.053, <i>d</i> = 0.37), it did not reach statistical significance, suggesting a trend toward lower body temperature, potentially reflecting enhanced thermoregulation.…"

Science Update: Precipitation and Snowfall in the Narragansett Bay Region حسب Narragansett Bay Estuary Program (8848544)

"…Linear regressions were performed to test for significance. Only statistically significant regressions are included on the figures.…"

Table 5_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls حسب Songqin Chen (9625886)

"…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…"

Table 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease: a m... حسب Shuyu Zheng (5570231)

"…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…"

Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d... حسب Sathivel Thivijan (20393742)

"…High-Performance Liquid Chromatography analysis revealed that while tartaric acid levels remained constant, malic acid content decreased, and acetic acid was produced by all strains. …"

Table 1_The interaction between temperature and rainfall determines the probability of tropical forest fire occurrence in Hainan Island.docx حسب Xiaohua Chen (257762)

"…The results show that: (1) climatic factors contribute most significantly to the tropical forest fire probability, followed by human activities and topography, while vegetation factors (i.e., normalized difference vegetation index) made no significant contribution; (2) temperature and rainfall are the dominant factors influencing fire probability, with rising temperatures and decreasing rainfall substantially increasing the forest fire hazard; and (3) both logistic regression and random forest are reliable for predicting tropical forest fire hazards, but random forest demonstrates greater adaptability. …"

Data Sheet 2_Divergent profiles of rhizosphere soil carbon and nitrogen cycling in Pinus massoniana provenances with different types of carbon storage.xlsx حسب Zichen Huang (6587885)

"…</p>Results<p>Our findings revealed a significant increase in the relative abundance of Acidobacteriota and Ascomycota by 23 and 61%, respectively, whereas Basidiomycota significantly decreased by 8% in the rhizosphere of P. massoniana provenances with high carbon storage compared with those with low carbon storage. …"

Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip حسب Xuanchun Huang (17359851)

"…Four of these factors were significantly causally related to the incidence of heart failure: CXCL9 and IFN-γ as promotive factors, and LIFR and UPA as potential protective factors. …"

Image 2_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg حسب Dylan Krajewski (5881880)

"…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …"

Table 4_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.docx حسب Yue Song (162328)

"…</p>Results<p>Both the low-frequency electroacupuncture group and the high-frequency electroacupuncture group significantly reduced writhing scores, increased spleen index, decreased prostaglandin PGF2α and COX-2 levels, and increased prostaglandin PGE2 and β-EP levels to varying degrees.…"

Data_Sheet_1_Air pollutants and ovarian reserve: a systematic review of the evidence.PDF حسب Roberta Zupo (8633919)

"…Background<p>Growing evidence indicates an association between ambient air pollution and decreased human reproductive potential. This study aims to systematically review the association between air pollutants and female ovarian reserve.…"

Image 3_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff حسب Tien Le (634791)

"…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…"

Image 4_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg حسب Kaisong Huang (5412626)

"…In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …"

Data Sheet 1_Craving on the move: targeting smoking memories with a novel 3MDR–smoking cessation protocol.pdf حسب Annel P. Koomen (20406923)

"…Smoking cue–induced craving and physiological measures were assessed at baseline (T0) and 1 day after the intervention (T4), and smoking behavior was measured at T0 and 2-week (FU1) and 3-month (FU2) follow-up.</p>Results<p>Significant decreases in cue-induced craving from T0 to T4 and daily cigarette use from T0 to FU1 and FU2 were observed but not differ between the two experimental groups. …"

Image_4_Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during Helicobacter pylori eradication: a randomized, double-blind,... حسب Zhongxue Han (19855215)

"…After treatment, the GSRS score decreased significantly in the probiotic group (p = 0.039). …"