Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx by Fahad Mubariz (16010003)

“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”

Data Sheet 1_Metabolism and immune responses of striped hamsters to ectoparasite challenges: insights from transcriptomic analysis.zip by Xinchang Lun (11996469)

“…By day 28, only SOD expression showed a significant decrease in both parasitism groups.</p>Conclusion<p>This study uncovered the dynamic changes in metabolism and immune responses of striped hamsters parasitized by Xenopsylla cheopis. …”

Supplementary file 1_Therapeutic effects of Balanites aegyptiaca DEL extract on diabetes mellitus: a systematic review.pdf by Olubukola Adebisi Odeniran (22162777)

“…All the studies were appraised for blood glucose levels, and a reduction in blood glucose was reported in all in vivo studies, regardless of the plant part used. Significant decrease in blood glucose level was recorded in Alloxan- and streptozotocin-induced rat/mice diabetes. …”

Table 1_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci... by Krzysztof Durkalec-Michalski (4691311)

“…The intervention had no significant effect on BM, FFM, FM, or TBW. BM, FFM (kg), TBW, and TBW/FFM were higher at SUP+FGB vs. …”

Supplementary Material for: Characteristics of asthmatic patients with IL18R1 differential expression in induced sputum by figshare admin karger (2628495)

“…IL18R1high asthma had a significant decrease in FeNO and more improvement in FEV1 during inhaled corticosteroid (ICS) treatment compared with patients having the IL18R1low subgroup. …”

Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

“…Introduction<p>The potential for drug-induced gastrointestinal (GI) toxicity is significant, since the GI tract is one of the first barriers which come in to contact with oral drugs. …”

Measurements per sample and cycle. by David Nora (10098723)

“…These two variables were measured, and the results correlated with the physical properties of various raw materials, including hardness and grain size. Our results show significant differences in the efficiency between the different types of raw materials. …”

Supplementary information files for "Dietary habits across the primary-secondary school transition: A systematic review" by Africa Peral-Suarez (20773982)

“…The frequency of consuming breakfast, fruit, vegetables, and milk decreased across the primary-secondary school transition. …”

Table 2_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Pre-existing peat organic matter remained relatively stable; significant priming of its consumption was not observed, nor was its structural alteration.…”

Data Sheet 1_Knowledge, attitude, and practice toward foodborne disease among Chinese college students: a cross-sectional survey.pdf by Xingming Ma (446316)

“…In particular, there was a notable decrease in practice scores toward foodborne diseases among male students, ethnic minority students, and non-medical students. …”

Table 1_DYRK1A roles in human neural progenitors.xlsx by Jeremie Courraud (20871932)

“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …”

Table 3_How does ego depletion reduce sports performance in athletes? A systematic meta-analysis.docx by Xu Yan (110026)

“…After sensitivity analyses using the Leave-One-Out method, two articles and one experiment were excluded with significant effect sizes. The final total effect size of ego depletion on athletes’ sports performance SMD = −0.38 [95% CI: −0.56 to −0.21], P = 0.001, demonstrating that ego depletion can produce a decrease in athletes’ sports performance. …”

Table 1_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.xlsx by Ethan C. J. Berry (21074345)

“…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”

Image_2_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.tif by Li Liu (75607)

“…Moderate spreading is conducive to the release of the aroma of tea leaves, but fixation causes a sharp decrease in the content of most volatile metabolites. …”

Table 6_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Pre-existing peat organic matter remained relatively stable; significant priming of its consumption was not observed, nor was its structural alteration.…”

Table_1_Abnormal outer and inner retina in a mouse model of Huntington’s disease with age.DOCX by Dashuang Yang (19956078)

“…Pathological assessments of the striatum and evaluations of motor function confirmed significant HD-related alterations in R6/1 mice at 6 months. …”

Supplementary Material for: Phase angle as an indicator of depression in maintenance hemodialysis patients by Li X. (3218241)

“…Median PhA level (interquartile range, IQR) of depressed patients was 4.4° (3.9-4.9°) for males and 3.9° (3.2-4.7°) for females. There was a significant decrease in the prevalence of depression with increasing quartiles of PhA levels. …”

Table_2_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”

Image 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.tif by Chengzhi Hou (20419865)

“…The higher levels of ALI and serum albumin were significantly associated with lower risks of all-cause and cardiovascular mortality among these individuals. …”

Table 1_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.docx by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”