Data Sheet 1_Integrative analysis of transcriptome and metabolome reveals molecular mechanisms of dynamic change of storage substances during dehydration and drying process in pean... حسب Jingjing Deng (468275)

"…S3d was the key period during which the content of most of the metabolites changed significantly. The contents of most amino acids(87%) and their derivatives decreased significantly, and most of the lipids(68%), sugars(67%) and flavonoids(87%) accumulated to their peak at S3d. …"

Table 1_Genome-wide analysis of lncRNA in wheat (Triticum aestivum) and functional characterization of TalncR9 in response to drought stress.xlsx حسب Lianzhe Wang (6202643)

"…Silencing TalncR9 in wheat reduced drought tolerance, decreased soluble sugar and proline levels, and increasing MDA levels. …"

Data Sheet 1_Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease.docx حسب Yifan Zhang (119570)

"…</p>Results<p>Sixty-four metabolites were significantly altered in PD patients compared to HC, with 58 elevated and 6 reduced. …"

Table 5_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx حسب Lili Deng (152262)

"…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …"

Short-term antiretroviral therapy may not correct the dysregulations of plasma virome and cytokines induced by HIV-1 infection حسب Yingying Ma (3617810)

"…These results suggest that short-term ART may not significantly correct the virome and cytokine dysregulations induced by HIV-1 infection. …"

Data Sheet 1_Lysate of Parabacteroides distasonis prevents severe forms of experimental autoimmune encephalomyelitis by modulating the priming of T cell response.docx حسب Zuzana Jiraskova Zakostelska (6386825)

"…EAE induction was the main factor in altering the gut microbiota, decreasing the abundance of lactobacilli and segmented filamentous bacteria. …"

Data Sheet 1_Dietary canthaxanthin improves egg production rate through regulating hepatic lipid metabolism and redox status in indigenous chickens.docx حسب Jie Chen (5892)

"…At week 9, 8 mg/kg CX significantly decreased serum MDA levels (p < 0.05). …"

Supplementary Material for: Using smartphone data to frequently measure atopic dermatitis severity and understand triggers: A decentralized 12-week observational study حسب Ali Z. (5634332)

"…Decreasing temperature was significantly associated with higher POEM (estimate -0.18, p=0.012) and EASI score (estimate -0.14, p=0.007), but not with SCORAD. …"

Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway حسب Zhan Y. (4157410)

"…In BV2 cells, LPS treatment decreased expression of BDNF, IL-10, and Arg1, while BDNF overexpression (BDNF-OE) significantly reversed the inflammation-induced by LPS by repressing iNOS and TNF-α, while increasing IL-10 and Arg1. …"

Supplementary Material for: High expression of tetraspanin CD63 predicts poor prognosis in esophageal squamous cell carcinoma حسب Matsumoto Y. (2866151)

"…Herein, we report the significance of CD63 expression by analyzing ESCC patient samples and ESCC cell lines. …"

Table 1_Nanocarrier-mediated RNAi of CYP9E2 and CYB5R enhance susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx حسب Farman Ullah (783297)

"…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9E2 genes significantly reduced their expression levels. Further, the activity of cytochrome P450 was substantially decreased after the knockdown of the CYB5R and CYP92 genes. …"

Supplementary file 1_Effects of human urine application on soil physicochemical properties, microbial communities, and enzymatic activities.docx حسب Guangquan Yu (21630101)

"…<p>Human urine (HU) is rich in nutrients necessary for plant growth, and recycling HU as fertilizer has multiple positive impacts, such as enhancing agricultural sustainability, reducing wastewater pollution, and decreasing reliance on chemical fertilizers, so it is of great significance to explore the effects of urine agricultural utilization on soil environment. …"

Table 1_Safety and efficacy comparison of single-stage and two-stage ERCP combined with laparoscopic cholecystectomy: a meta-analysis and systematic review.xlsx حسب Jian-Xiong Tai (22696688)

"…The incidence of pancreatitis was significantly higher in the sequential surgery group compared to LERV (RR = 1.90, 95% CI: 1.61–2.24). …"

Data Sheet 1_Investigating the underlying mechanisms of the ethanol extract of saussureae involucratae herba in anti-rheumatoid arthritis effect based on sphingolipidomics.pdf حسب Pingyuan Chi (21563069)

"…In cell assays, SIE significantly decreased the protein levels of TNF-α and IL-6 (both P < 0.01) in LPS-stimulated RAW 264.7 cells. …"

Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway حسب figshare admin karger (2628495)

"…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …"

Table 1_Nanocarrier-mediated RNAi of CYP9A306 and CYB5R enhances susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx حسب Farman Ullah (783297)

"…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9A306 genes significantly reduced their expression levels. Further, the activity of cytochrome P450 was substantially decreased after the knockdown of the CYB5R and CYP9A306 genes. …"

Table 1_The relationship between positive future thinking, entrapment, defeat and death-related mental imagery in individuals with and without a suicidal history: an experimental s... حسب Gonca Köse (21477470)

"…Mean scores for PFT from pre-to post-negative mood induction decreased significantly in the participants with a history of suicidal thoughts/behaviours but not in those without a suicidal history. …"

Data Sheet 1_Stand structure influences understory plant diversity through soil factors: three afforestation types of Masson’s pine in the upper Yangtze River, China.docx حسب Yongqi Xiang (12548293)

"…In terms of stand structure, MCLMF significantly increased the opening degree (O), mingling index (M), and competition index (CI), while MLMF decreased CI but increased M. …"

Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX حسب Mingming Zhao (760369)

"…Only three bile acid metabolites, taurodeoxycholic acid, taurochenodeoxycholic acid, and deoxycholic acid, were significantly different between the ANLF1 and ANLF2 groups, increasing at first and then decreasing with the aggravation of liver injury. …"

Table 2_Safety and efficacy comparison of single-stage and two-stage ERCP combined with laparoscopic cholecystectomy: a meta-analysis and systematic review.docx حسب Jian-Xiong Tai (22696688)

"…The incidence of pancreatitis was significantly higher in the sequential surgery group compared to LERV (RR = 1.90, 95% CI: 1.61–2.24). …"