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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
less decrease » teer decrease (Expand Search), we decrease (Expand Search), levels decreased (Expand Search)
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15501
AI KRegression
Published 2025“…Further examining the nonlinear interaction coupling indicators, NLID(X|Y) decreased from 0.736 ± 0.185 to 0.654 ± 0.182 (p = 0.013*), and NLID(Y|X) decreased from 0.747 ± 0.151 to 0.698 ± 0.155 (p = 0.030*), clearly revealing the significant weakening of the nonlinear driving relationship between the two axes under fatigue state. …”
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15502
Variance of the first 20 principal components from the essential dynamics analysis of the unbiased MD simulation of GumK in the membrane-bound state.
Published 2025“…<p>The first five principal components are sufficient to define the essential subspace, as the individual variance decreases sharply after the fifth component and approaches an asymptotic value. …”
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15503
Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
Published 2025“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”
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15504
Table 2_Prevalence of pathogens from clinical samples associated with porcine respiratory and digestive diseases in South Korea from 2021 to 2023.docx
Published 2025“…The trends in 3-year prevalence showed no significant changes, but in 2023, viral infections (e.g., PRRSV, Rotavirus, porcine epidemic diarrhea virus, etc.) decreased and bacterial infections (e.g., Mycoplasma hyopneumoniae (MH), Pasteurella multocida (PM), Haemophilus parasuis (HP), Salmonella spp., Lawsonia intracellularis, and Brachyspira hyodysenteriae) slightly increased (χ<sup>2</sup> = 11.36, P < 0.001). …”
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15505
Image 3_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”
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15506
Table 1_Prevalence of pathogens from clinical samples associated with porcine respiratory and digestive diseases in South Korea from 2021 to 2023.docx
Published 2025“…The trends in 3-year prevalence showed no significant changes, but in 2023, viral infections (e.g., PRRSV, Rotavirus, porcine epidemic diarrhea virus, etc.) decreased and bacterial infections (e.g., Mycoplasma hyopneumoniae (MH), Pasteurella multocida (PM), Haemophilus parasuis (HP), Salmonella spp., Lawsonia intracellularis, and Brachyspira hyodysenteriae) slightly increased (χ<sup>2</sup> = 11.36, P < 0.001). …”
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15507
Image 3_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
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15508
The effects of emotional expressivity and self-efficacy levels of individuals with substance addiction on treatment compliance
Published 2025“…</p> <p>In the present study, the emotional expressivity total score average of the participants was found to be 26.53 ± 9.03, their self-efficacy/sufficiency total score average was 74.15 ± 14.84, and their treatment compliance total score average was 85.27 ± 17.25. A negative and significant relationship was detected between the TCS total score and the EES total score of the participants, and there was a positive and significant relationship with the SES total score average (<i>p</i> < .05).…”
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15509
Image 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”
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15510
Table 5_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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15511
Table 1_Dietary caffeine and its negative link to serum Klotho concentrations: evidence from the National Health and Nutrition Examination Survey.docx
Published 2024“…Subgroup analyses indicated that this association was more significant in participants with sedentary activity >480 min and without hypertension.…”
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15512
Data Sheet 1_Global, regional, and national burden of fracture of vertebral column, 1990–2021: analysis of data from the global burden of disease study 2021.docx
Published 2025“…Background<p>Fractures of the vertebral column, encompassing various spinal injuries, represent a significant public health burden worldwide. These injuries can lead to long-term disability, reduced quality of life, and substantial healthcare costs.…”
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15513
Image 2_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…</p>Results<p>In 2019, lead exposure-related ischemic stroke caused a significant disease burden, with males and middle-aged/older adults disproportionately affected. …”
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15514
Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx
Published 2025“…<p>Lavender (Lavandula angustifolia Mill.) is a valuable aromatic plant with significant commercial importance. However, cold stress–one of the primary abiotic factors impacting sugar metabolism–adversely affects its agricultural productivity in Northeast China. …”
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15515
Data Sheet 1_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf
Published 2025“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”
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15516
Data Sheet 1_Effects of irrigation and fertilization management on kiwifruit yield, water use efficiency and quality in China: A meta-analysis.zip
Published 2025“…However existing kiwifruit water-saving and fertilizer-reduction studies showed significant contradictions in the results of water and fertilizer management. …”
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15517
Table 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.xlsx
Published 2025“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”
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15518
Table 2_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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15519
Table 1_Global, regional, and national burden of liver cancer in adolescents and young adults from 1990 to 2021: an analysis of the global burden of disease study 2021 and forecast...
Published 2025“…East Asia bears the highest burden, with males experiencing significantly higher rates than females. The burden increases with age, peaking at 35–39 years. …”
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15520
Image 7_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”