Data Sheet 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…Background<p>Charged Multivesicular Body Protein 4A (CHMP4A), a member of the ESCRT-III family, plays a pivotal role in membrane remodeling and fission, with emerging evidence underscoring its significance in cancer immunotherapy. The complex pathogenesis and therapeutic resistance characteristic of liver hepatocellular carcinoma (LIHC) present significant challenges in clinical practice. …”

Table_1_Refugees’ integration and emotional distress over the course of 9 months.pdf by Flurina Potter (16537140)

“…</p>Results<p>Overall, emotional distress decreased, and integration increased over time. In particular, the sub-dimensions of social, economic, and linguistic integration increased significantly over time<sub>.…”

Data Sheet 1_Exogenous putrescine modulates variety-specific cadmium tolerance in wheat seedlings: synergistic roles of antioxidant defense and physiological homeostasis.pdf by Dandan Zhong (388523)

“…Introduction<p>Cadmium (Cd) contamination in farmland is a significant environmental issues affecting crop yields. …”

Table 4_The association of diabetic retinopathy and diabetic kidney disease in patients with type 2 diabetes mellitus: a prospective observational research study.xlsx by Yutong Wu (3130584)

“…Background<p>Diabetic retinopathy (DR) and diabetic kidney disease (DKD) are two prevalent diabetic complications significantly influencing global health and quality of life. …”

Table 1_The association of diabetic retinopathy and diabetic kidney disease in patients with type 2 diabetes mellitus: a prospective observational research study.xlsx by Yutong Wu (3130584)

“…Background<p>Diabetic retinopathy (DR) and diabetic kidney disease (DKD) are two prevalent diabetic complications significantly influencing global health and quality of life. …”

Data Sheet 1_Global, regional, and national burden of thyroid cancer in women of child-bearing age, 1990 to 2021 and predictions to 2035: An analysis of the global burden of diseas... by Tao Jiang (28401)

“…The Estimated Annual Percentage Change (EAPC) for ASIR was 1.47, indicating an increasing trend, whereas the EAPCs for ASMR and ASDR were -0.35 and -0.05, showing decreasing trends. The burden of thyroid cancer among patients with women of child-bearing age exhibited a significant age-related trend, peaking in the 45–49 age group. …”

Image 1_Multi-omics analysis reveals the alleviating effect of oxidation remediation on tobacco quinclorac stress.jpeg by Binghui Zhang (10898910)

“…Metagenomic analysis found that quinclorac significantly reduced soil species diversity, while K₂S₂O₈-based remediation soil exhibited higher richness of microbial communities, with increased abundance of Sphingomonas and Bradyrhizobium, and decreased abundance of Alphaproteobacteria. …”

Table 1_Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats.xlsx by Longping He (18492915)

“…The EHS group showed significantly prolonged PT and APTT, increased Lac, decreased platelet count, and elevated plasma levels of TM, vWF, TSP-1, and PAI-1 compared to the NC group (P < 0.05). …”

Table 3_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.docx by Jiaoli Xu (20871584)

“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”

Table 4_Inoculation frequency and maize genotype influence plant growth-promoting effects of soil bacteria under low nitrogen conditions.xlsx by Lexie R. Foster (22235653)

“…In addition, our results showed a significant growth response to repeated inoculations with a beneficial bacterial isolate. …”

Table 1_Antiepileptic drugs and foetal disorders: analysis of 20-year data from the pharmacovigilance center.docx by Zejun Ji (20787176)

“…</p>Results<p>The study identified significant correlation between foetal disorders and the first and second generation AEDs, with RORs of 3.8 and 4.9, respectively. …”

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> by Elena Suleymanova (22195777)

“…We also observed disruption of the IGF system, characterized by decreased IGFBP-5 protein levels in the hippocampus and downregulation of <i>Igfbp5</i> mRNA in both hippocampus and cortex. …”

Data Sheet 1_Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models... by Shreshta Jain (12274885)

“…</p>Results<p>Decanoic acid significantly improved learning and memory performance, enhanced antioxidant enzyme activity (superoxide dismutase, reduced glutathione, catalase), promoted autophagy by inhibiting mTOR, reduced cellular senescence (β-galactosidase-positive cells), and decreased amyloid-β toxicity. …”

Table_2_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX by Enas Al-khlifeh (17286364)

“…We found that bioclimatic zone had a significant effect on the gut microbiota composition while host phylogeny did not. …”

Data Sheet 1_Adolescent brain maturation associated with environmental factors: a multivariate analysis.pdf by Bhaskar Ray (18575134)

“…These specific brain characteristics were significantly more pronounced in the accelerated brain aging group compared to the delayed group. …”

Supplementary Material for: The power of a good word: Enhancing the efficacy of analgesics in clinical settings by Treister R. (19801920)

“…In study 2, in the last two timepoints of assessment, participants in the EC arm also consumed fewer doses of opioids than participants in the RC arm (p<0.001). No significant differences were found in vital signs. Conclusions: We provide ecological evidence that positive information about treatment significantly decreases pain and opioid consumption during routine clinical care. …”

Surface Modification of Islets with L-DOPA-KF7 Enhances Islet Survival by Inhibiting IBMIR in Intrahepatic Islet Transplantation by Daopeng Yang (9701019)

“…Islets coated with L-DOPA-KF7 restored normoglycemia in diabetic mice, and survival time was significantly longer compared to control group. Transplantation of L-DOPA-KF7 coated islets was associated with reduced blood clot formation and decreased infiltration of CD11b+ cells and platelets. …”

Table 1_Unveiling neuroimmunology profile of immunological non-responders in HIV: a multimodal MRI approach.docx by Yang Zhang (30734)

“…Furthermore, INRs exhibited significant alterations in functional connectivity in the temporal and occipital gyrus. …”

Supplementary file 1_Structural and functional disconnections in non-acute post-stroke patients.docx by Yanan Wu (290695)

“…</p>Results<p>Compared with HCs, significant decreases in both SC and FC were observed in stroke patients among the right precentral gyrus, right superior frontal gyrus, right supplementary motor area, right paracentral lobule, right middle cingulate gyrus, right superior marginal gyrus, right middle temporal gyrus, and left inferior temporal gyrus. …”

Table 1_Assessment the relationship between health anxiety and iranian nurses’ quality of life: a cross-sectional study.docx by Zahra Amoozadeh (20944724)

“…</p>Conclusion<p>This study showed that there is a significant relationship between health anxiety and different dimensions of quality of life, so that the quality of life of nurses decreases with the increase of health anxiety.…”