Multimorbidity and health related quality of life in midlife – a longitudinal study from Northern Finland Birth Cohort 1966 by Oili Junttila (21337262)

“…</p> <p>In general, HRQoL decreased during 15-year follow-up for everyone. Furthermore, decrease in the quality of life is significantly associated with multimorbidity in this longitudinal setting.…”

Table 5_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…Early detection and removal of precancerous lesions during the adenoma-carcinoma sequence can significantly reduce CRC risk. However, current clinical practice lacks rapid, noninvasive screening tools for reliable adenoma detection.…”

Ganaxolone: A Review in Epileptic Seizures Associated with Cyclin‑Dependent Kinase‑Like 5 Deficiency Disorder by Sheridan M. Hoy (4897468)

“…In a multinational phase III study (Marigold), 17 weeks’ therapy with adjunctive ganaxolone, administered orally three times daily with food, significantly reduced 28-day major motor seizure frequency from baseline versus placebo in patients aged 2–19 years with CDD-associated refractory epilepsy. …”

Data Sheet 1_Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study.docx by Ameya Joshi (1290186)

“…The non-specific inhibitor Vorinostat surprisingly promoted migration in the cells at its 2D IC50 value treatment, and none of the inhibitors was able to significantly decrease late resistance compared to untreated controls, indicating the need for the development of more potent HDAC inhibitors for monotherapy for GBM.…”

Data Sheet 1_Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat.pdf by Robert M. N. Tran (20539130)

“…Heart rate (HR) was significantly decreased after administration of lidocaine (344 ± 32 to 289 ± 47 bpm; p = 0.015, pre-vs. after-injection), but not after normal saline, into the right SG. …”

Data Sheet 1_Synchronized nutrition fertilizer improves soil microbial diversity and sugarcane yield through agrochemical and enzymatic regulation.docx by Xiuxiu Qi (22354858)

“…</p>Results<p>Results showed that yield, °Brix in the SNFert, even with 15% and 25% less fertilizer input, were no significant differences with those of CF. …”

Study of monopolar plate springback applying zoned multistage forming process by Jiabo Zhang (10076842)

“…The length and width of an MPP both exceed 150 mm, but the thickness of its raw material plate is less than 0.1 mm, posing a significant challenge to the uniformity of its thickness after forming. …”

Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing <i>Klebsiella pneumoniae</i> by Yingying Du (5877701)

“…<p>Carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. …”

Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf by Fisal Tantoush (20936264)

“…<p>Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor immunization responses afflict patients. …”

Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds by Wen Gu (129075)

“…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i>_E), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …”

Supplementary Material for: Fetoscopic endoluminal tracheal occlusion in congenital diaphragmatic hernia: Unraveling the impact of prematurity and suboptimal fetal lung growth by figshare admin karger (2628495)

“…In univariate analyses, the balloon inflation duration (p=0.05), the use of extracorporeal life support (p=0.04), and the post-balloon o/e LHR (p=0.04) were associated with survival, while in a multivariable logistic regression, the change in o/e-LHR after FETO (OR=1.07, p=0.05) was the only variable found to be significantly associated with survival. Conclusion Prematurity and SFLG are critical factors linked to decreased survival in FETO, with improved o/e-LHR correlating with better outcomes. …”

pone.0331193.t003 - by Carol Kotliar (22351525)

“…</p><p>Background</p><p>Cognitive decline is a significant concern in aging populations, with research suggesting that neuroplasticity and cognitive reserve can be enhanced through targeted cognitive training. …”

E4 assessment of physiological measures (Kondaurova et al., 2024) by Maria V. Kondaurova (19751735)

“…Children self-reported a significant increase in LE over time. However, their physiological measures demonstrated a trend indicating a decrease in LE. …”

Effect of amikacin-humic acid combination on <i>Acinetobacter baumannii</i> biofilm: an <i>in vitro</i> and <i>in silico</i> study by Seetha Lakshmi Rajangam (19921021)

“…The images observed via Scanning Electron Microscope (SEM) showed a significant decrease in the biofilm matrix. Confocal Laser Scanning Microscope (CLSM) confirmed a reduction of the Z value of its three-dimensional structure. …”

Baseline characteristics by group. by Carol Kotliar (22351525)

“…</p><p>Background</p><p>Cognitive decline is a significant concern in aging populations, with research suggesting that neuroplasticity and cognitive reserve can be enhanced through targeted cognitive training. …”

Engineered deletions of 1-TbAd biosynthesis genes reveal gene functions and greatly expand the lipid signature. by Jacob A. Mayfield (19762468)

“…Events with >4-fold decrease in all 3 mutants and <i>p</i> < 0.001 (Benjamini–Hochberg adjusted <i>p</i> value of the F-test) are shown in black. …”

Proteomic and phosphoproteomic time course over sexual differentiation. by Melvin Bérard (7907558)

“…(<b>C</b>) Table displaying the number of phosphosites with significant changes during starvation (top 2 lines) and with significant difference between mating and starvation conditions (bottom 2 lines); 272 (156 + 116) sites changed specifically during mating, after correction by the starvation values. …”

Supplementary file 1_“We find that…” changing patterns of epistemic positioning in research writing.docx by Yanfang Yang (408813)

“…</p>Results<p>Our findings show that epistemic positioning has significantly decreased across all four disciplines over time, with writers increasingly preferring less use of epistemic markers in pursuit of an objective, data-based, and scientific style.…”

Image 1_Emphysema-related mortality rates in the U.S. from 1999 to 2022.pdf by Alexandra Brown (225908)

“…</p>Discussion<p>Emphysema-related deaths in the United States decreased overall between 1999 and 2022, likely a result of a greater emphasis on health education concerning the significant dangers of smoking and policy changes that made cigarettes less accessible and less affordable, and more available access to resources and support networks.…”

Supplementary file 1_Mitigating salt stress in saline-alkali soils through co-application of superabsorbent carbon-based material and flue gas desulfurization gypsum.docx by Shengnan Zhang (1340988)

“…The CB+FGD treatment significantly reduced soil TSS, electrical conductivity (EC), and SAR. …”