Supplementary Material for: Diverse Obesity Trajectories in a Family including Identical Twins with a Pathogenic MC4R Variant by figshare admin karger (2628495)

“…Twin 2 had a sedentary lifestyle and epilepsy and had a peak BMI of 30.1 kg/m2; she responded well to naltrexone-bupropion and BMI decreased to 26 kg/m2. Conclusion: The manifestation of obesity, even in cases of monogenic obesity, can vary significantly due to the influence of environmental and lifestyle factors.…”

Strategy parameters across development for male mice in set size = 2 and set size = 4 from winning computational model. by Juliana Chase (20469427)

“…Both parameters S1 “Inappropriate Lose-Shift” and S3 “Inappropriate Lose-Stay” decreased significantly with age in set size = 2 (C: <i>p</i> = 0.02, E: <i>p</i> = 0.04), but not in set size = 4 (H,J). …”

DataSheet1_The impact of statin use on short-term and long-term mortality in patients with heart failure.docx by Xiaoxue Zheng (433886)

“…Low-dose statins can significantly reduce short-term and long-term mortality, while high-dose statins are not significantly correlated with mortality. …”

Mapping global urban inequality under climate change and its interaction with sustainable development by Yinshuai Li (20382495)

“…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …”

Table_2_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table_3_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table_1_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xlsx by Ying He (125930)

“…The gene expression profiles of isolated CD11b+Ly6G+Ly6C^lo cells were studied by RNA sequencing. We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Effects of vidarabine, V2E, V3E and V5E on cardiac fibrosis. by Kenji Suita (750993)

“…(B) Chronic ISO infusion significantly increased the area of fibrosis in cardiac muscle but this increase was significantly decreased by Vida, V2E, V3E and V5E. …”

Exploring the effects of COVID-19 on verbal memory function in schizophrenia: Multiple case study and brief literature review by Barbora Keřková (15125926)

“…We calculated the Reliable Change Index to estimate the clinical significance of verbal memory performance changes, with annualized change rates in hippocampal volumes assessed against normative data. …”

Supplementary file 1_Biodegradation potential of Gordonia spp. on polypropylene and polystyrene: enhanced degradation through pretreatment.docx by Yan Zhu (112437)

“…Introduction<p>As extensively utilized synthetic polymers, polypropylene (PP) and polystyrene (PS) have raised significant environmental concerns due to their persistent accumulation in ecosystems.…”

Table1_Recovery of Coilia nasus resources after implementation of the 10-year fishing ban in the Yangtze River: implied from the Yangtze River Estuary and its adjacent sea areas.do... by Shuyan Wang (397236)

“…The total mortality rate, fishing mortality rate, and exploitation rate were determined to be 1.47 year^-1, 0.79 year^-1, and 0.54, respectively. (4) LBB estimated that the relative fishing mortality of C. nasus before the fishing ban increased from 1.22 in 2019 to 2.65 in 2020, while the relative biomass decreased from 0.34 to 0.22. After the fishing ban, the relative fishing mortality decreased from 0.85 in 2021 to 0.06 in 2023, and the relative biomass increased from 0.26 in 2021 to 0.90 in 2023, with a significant increase in 2022, indicating a clear recovery trend in C. nasus resources.…”

Data Sheet 1_Deciphering ERR family genes as prognostic and immunological biomarkers through pan-cancer analysis with validation in gallbladder cancer.pdf by Wanwan Gong (21187838)

“…All three ERRs demonstrate significant prognostic value across different cancers. …”

<b>Feeding Ecology of the Critically Endangered </b><b><i>Gobio insuyanus </i></b><b>(Gobionidae)</b> by Julian E. JOHNSON (20653776)

“…No significant dietary differences were found between the sexes. …”

Pythagorean Self-Awareness Intervention for Alcohol Relapse Prevention: A Randomized Pilot Controlled Trial by Christina Dimopoulou (20809053)

“…Our results underscore the statistically significant advantages of PSAI, such as enhancements in cognitive functions, healthy lifestyle practices, and sleep quality, as well as decreases in stress levels, cortisol concentration, and alcohol consumptions. …”

<b>Metabolic Perturbations and Ectopic Fat Deposition in Low Birthweight Subjects</b><b>– Effects of a 4 Week Carbohydrate Overfeeding Challenge</b> by Charlotte Brøns (261017)

“…Subcutaneous adipose tissue (SAT) density was lower in LBW subjects and decreased during COF in both groups. Serum alanine, phosphatidylcholines, and triglycerides increased significantly more in LBW subjects during COF. …”

Supplementary Material for: Association of Two Neonatal Encephalopathy Scores with Neurophysiology in Newborns with Suspected Hypoxic Ischemic Encephalopathy by figshare admin karger (2628495)

“…Conclusions: Both NE scores showed a significant correlation with neurophysiology, but NE scores have limitations. …”

Data Sheet 1_A systematic review of the effects of nanoplastics on fish.pdf by Asok K. Dasmahapatra (2275549)

“…NAP exposure leads to significant adverse effects including increased oxidative stress, decreased locomotor and foraging activities, altered growth, immunity, lipid metabolism, and induced neurotoxicity. …”

India-Asia collisional processes: constraints from the Eocene magmatic rocks in the southern Tibetan Plateau by Li-Qiang Zhang (1312050)

“…The La/Yb, Sm/Yb, and Dy/Yb values are widely used for the quantitative inversion of crustal thickness. We found that the La/Yb, Sm/Yb, and Dy/Yb values of 70–40 Ma intermediate-acidic magmatic rocks in the southern Tibetan Plateau began to increase from ca. 58 Ma, reached a peak at ca. 52 Ma, and then slowly decreased, indicating that crustal thickening-thinning processes may have occurred during the Eocene and crustal thickening peaked at ca. 52 Ma. …”

Comparison of opioid use among long-term care residents in Ontario and Alberta, Canada: A multi-jurisdictional, repeated cross-sectional study by Colleen J. Maxwell (3818041)

“…In both provinces, there were significant decreases in higher risk opioid prescribing over time, including concurrent use with benzodiazepines, but also significant increases in the concurrent use with gabapentinoids and tramadol use (Alberta only).…”

Table 2_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.docx by Yaser Shabanpour (13247160)

“…<p>Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation of polyunsaturated fatty acids (PUFAs). Despite its significance, the precise molecular mechanisms underlying ferroptosis remain elusive, particularly concerning their impact on membrane properties. …”