Data Sheet 1_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.xlsx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Supplementary file 1_Global, regional, and national burdens of MDR-TB attributable to smoking from 1990 to 2021 with a prediction from 2022 to 2050.docx by Du Dan (22274296)

“…Predictive analysis suggests that by 2050, deaths and DALYs of smoking-related MDR-TB, as well as their corresponding ASR, will continue to decrease.</p>Conclusion<p>The burden of MDR-TB worldwide, adjusted for age, and related to smoking, has shown a decline from 1990 to 2021. …”

Data Sheet 2_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.docx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Table_1_Engaging Underserved Communities in COVID-19 Health Equity Implementation Research: An Analysis of Community Engagement Resource Needs and Costs.docx by Nicole A. Stadnick (8788511)

“…Needed resources decreased, albeit with a greater diversity of activities, in later phases of community engagement with Spanish language translation requiring most in the later stage of the study. …”

Trends and Disparities in Rates of Hypoglycemia Among Hospitalized Patients with Type II Diabetes by Paul A Heidenreich (13188712)

“…After adjustment for other patient characteristics, the youngest and oldest patients, and those hospitalized in earlier years (vs. 2022) had significantly higher rates of hypoglycemia. Black (adjusted odds ratio -aOR, 1.42 95% CI 1.36-1.49) or Hispanic patients (aOR 1.26 95% CI 1.17-1.35) had a greater risk of hypoglycemia compared with non-Hispanic White patients and women had borderline less hypoglycemia than men (aOR 0.95, 95% CI 0.89-1.00)</p><p dir="ltr">Conclusion: Inpatient hypoglycemia in the VA Health System has been declining though there are race, age and gender differences that remain unexplained. …”

Rescue of <i>pbp1</i>-KD phenotypes using CRISPRi trans-complementation. by Gregory A. Harrison (16639446)

“…Yellow arrows point to a subset of PBP1-depleted cells that have decreased RADA signal, likely due to decreased peptidoglycan metabolism. …”

Data Sheet 1_Impact of finerenone on chronic kidney disease progression in Chinese patients with type 2 diabetes: a FIGARO-DKD subgroup analysis.docx by Ping Li (31981)

“…Finerenone resulted in a numerical decrease in the risk of the cardiovascular composite outcome (hazard ratio 0.91; 95% confidence interval 0.50–1.67) and a significantly reduced risk of the key secondary kidney outcome (hazard ratio 0.48; 95% confidence interval 0.29–0.79; p = 0.0029). …”

The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... by Mohammed A. Altowijri (22461945)

“…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …”

Table 1_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…To further examine the dose–response relationship, restricted cubic spline models were employed to assess potential non-linear associations.</p>Results<p>Increased total physical activity [hazard ratio (HR) = 0.978; 95% confidence interval (CI): 0.961–0.995, P = 0.011], moderate-to-vigorous PA (HR = 0.960; 95% CI: 0.929–0.992, P = 0.014), and moderate physical activity (MPA) (HR = 0.953; 95% CI: 0.918–0.990, P = 0.014) were significantly associated with a decreased risk of major adverse cardiovascular events, respectively. …”

Table 2_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…To further examine the dose–response relationship, restricted cubic spline models were employed to assess potential non-linear associations.</p>Results<p>Increased total physical activity [hazard ratio (HR) = 0.978; 95% confidence interval (CI): 0.961–0.995, P = 0.011], moderate-to-vigorous PA (HR = 0.960; 95% CI: 0.929–0.992, P = 0.014), and moderate physical activity (MPA) (HR = 0.953; 95% CI: 0.918–0.990, P = 0.014) were significantly associated with a decreased risk of major adverse cardiovascular events, respectively. …”

Supplementary file 1_Short-term fasting before living kidney donation has an immune-modulatory effect.pdf by Christiaan A. J. Oudmaijer (12006320)

“…STF changes the levels and phenotype of immune cells, reducing the abundance and activation of T cells, including regulatory T cells, increased presence of (naïve) B cells, and elevation of type 1 conventional DCs (cDC1s). In addition, a decrease in central memory T cells was observed.…”

Data Sheet 1_Short-term fasting before living kidney donation has an immune-modulatory effect.docx by Christiaan A. J. Oudmaijer (12006320)

“…STF changes the levels and phenotype of immune cells, reducing the abundance and activation of T cells, including regulatory T cells, increased presence of (naïve) B cells, and elevation of type 1 conventional DCs (cDC1s). In addition, a decrease in central memory T cells was observed.…”

Table 1_Gut microbiota alterations and systemic inflammation in community-acquired pneumonia: a prospective gut-lung axis study.docx by Xue-Qin Yang (3494345)

“…The abundance of short-chain fatty acid-producing genera in CAP patients decreased significantly, such as Blautia and Agathobacter. …”

Table 1_Disc degeneration influences the strain magnitude and stress distribution within the adjacent trabecular bone.docx by Kay A. Raftery (17080234)

“…Von Mises stress distribution was significantly skewed towards the anterior region in the degenerated group only (28.3% ± 10.4%, p < 0.05). …”

Model-derived results show increased social following in individuals with disrupted utility-based risky decision-making. by Mark A. Orloff (20371158)

“…<p><b>(a)</b> Parameter estimates across all trials showed that individuals with insula or dACC lesions had significantly larger ω_follow estimates than non-lesioned control participants (NC; NC vs insula: <i>P</i> = 0.036; NC vs dACC: <i>P</i> = 0.025; dACC vs insula: <i>P</i> = 0.89, BF_null = 2.28), indicating that the lesion participants were more likely to conform with others’ choices during decision-making in a social context. …”

Data Sheet 1_Global burden of cancer in adolescents and young adults aged 10–24 years: a trend analysis.pdf by Junjun Yang (307892)

“…The age-standardized death rate(ASDR) and age-standardized DALY rate of total cancer have decreased significantly globally in adolescents and young adults aged 10–24 years. …”

Table 2_The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990–2019 in China.docx by Yongyao Shen (20561210)

“…Despite a slight decreasing trend exists, the absolute number increased as much as twofold, particularly among males and seniors. …”

Table 1_The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990–2019 in China.docx by Yongyao Shen (20561210)

“…Despite a slight decreasing trend exists, the absolute number increased as much as twofold, particularly among males and seniors. …”

An improved <i>in vitro</i> 3T3-L1 adipocyte model of inflammation and insulin resistance by Ifeoluwa A. Odeniyi (19862796)

“…Importantly, insulin resistance and inflammation were still induced in the 12 h treated adipocytes: the expression of the insulin sensitive and inflammatory genes was decreased and increased, respectively. In 72 h treated adipocytes, no significant differences were found in the viability, glucose uptake or insulin-sensitive and inflammatory gene expression. …”

Table 1_Development of the breastfed infant oral microbiome over the first two years of life in the BLOSOM Cohort.docx by Roaa A. Arishi (21089924)

“…Introduction of solid foods was a significant milestone in oral microbiome development, triggering an increase in bacterial diversity (richness P = 0.0004; Shannon diversity P = 0.0007), a shift in the abundance of seven species, and a change in beta diversity (P = 0.001).…”