Image 5_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Image 2_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Image 4_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Data Sheet 1_miR-198 targets TOPORS: implications for oral squamous cell carcinoma pathogenesis.pdf by Pankhuri Kaushik (20381022)

“…An inverse correlation between the expression levels of miR-198 and TOPORS is observed in OSCC patient samples, highlighting the biological relevance of their interaction. Delivery of a synthetic miR-198 mimic to OSCC cells results in a significant decrease in xenograft size in nude mice, potentiating its use in therapeutics.…”

Image 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Table 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.docx by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Supplementary file 1_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…In vivo experiments showed that AM-CO could induce autophagy, an increase in LC3II expression and a decrease in P62 expression. Meanwhile, in vitro experiments showed that Cal could also increase the expression of LC3II and inhibit the protein expression levels of p62, PI3K, P-AKT and AKT. …”

Image_4_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.TIFF by Juan P. Frene (12227753)

“…In both fungal and bacterial/archaeal communities, J. nigra and Q. rubra notably decreased the number of connections within their networks, while Q. rubra increased some, suggesting a more interconnected network. …”

Image_1_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.PDF by Juan P. Frene (12227753)

“…In both fungal and bacterial/archaeal communities, J. nigra and Q. rubra notably decreased the number of connections within their networks, while Q. rubra increased some, suggesting a more interconnected network. …”

Image_5_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.TIFF by Juan P. Frene (12227753)

“…In both fungal and bacterial/archaeal communities, J. nigra and Q. rubra notably decreased the number of connections within their networks, while Q. rubra increased some, suggesting a more interconnected network. …”

Supplementary file 2_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…In vivo experiments showed that AM-CO could induce autophagy, an increase in LC3II expression and a decrease in P62 expression. Meanwhile, in vitro experiments showed that Cal could also increase the expression of LC3II and inhibit the protein expression levels of p62, PI3K, P-AKT and AKT. …”

Pond consolidation in the northwest Prairie Pothole Region changes water boatman (Hemiptera: Corixidae) species composition and reduces potential contribution to seasonal mass-migr... by Alexander Lapierre (22478656)

“…We found a non-significant decrease in species richness due to pond consolidation. …”

Image_2_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.TIFF by Juan P. Frene (12227753)

“…In both fungal and bacterial/archaeal communities, J. nigra and Q. rubra notably decreased the number of connections within their networks, while Q. rubra increased some, suggesting a more interconnected network. …”

Data_Sheet_1_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.xlsx by Juan P. Frene (12227753)

“…In both fungal and bacterial/archaeal communities, J. nigra and Q. rubra notably decreased the number of connections within their networks, while Q. rubra increased some, suggesting a more interconnected network. …”

Supplementary file 1_Analysis of gender- and age-stratified asthma burden: forecasting prevalence trends in 2030.docx by Zhenzhen Pan (2637463)

“…In China, smoking emerged as a significant risk factor for men, while the risk associated with high body mass index (BMI) has increased notably in recent years. …”

Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration by Xinyi Zhang (36040)

“…Under oxidative and hyperglycemic culture conditions, we validated the zcg mechanism of blocking the AGEs-ROS cycle, restoring fibroblast mitochondrial membrane potential, and subsequently suppressing cellular senescence. In a bacterial-infected diabetic rat skin wound model, the zcgG group demonstrated substantially reduced inflammatory levels, a 68% decrease in AGEs, and a 1.9-fold increase in collagen deposition compared to blank controls. …”

Image_3_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.TIFF by Juan P. Frene (12227753)

“…In both fungal and bacterial/archaeal communities, J. nigra and Q. rubra notably decreased the number of connections within their networks, while Q. rubra increased some, suggesting a more interconnected network. …”

Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Routine blood tests revealed significantly elevated neutrophil granulocytes and monocytes, along with a marked decrease in lymphocytes. …”

Supplementary file 1_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Routine blood tests revealed significantly elevated neutrophil granulocytes and monocytes, along with a marked decrease in lymphocytes. …”

Table 1_The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae.xlsx by Xiaoyu Zhang (62901)

“…Additionally, invasive procedures (such as history of tracheostomy, use of ventilators for >96 h, and craniotomy) were also significant predictive factors. The Nomogram indicated that CRKP, presence of a nasogastric tube, admission to the ICU, and history of tracheostomy were important factors in determining KP colonization.…”