Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Meanwhile, compared to the groups treated with either IFNβ or RSL3 alone, the combination treatment of IFNβ and RSL3 significantly inhibited the growth of HT1080 three-dimensional (3D) spheroids and tumor in a mouse xenograft model.…”

Table 2_Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.xlsx by Lu An (3432230)

“…Long-term exposure to particulate matter (PM)2.5 and PM10 is associated with a substantial decrease in ovarian reserve, while heavy metals (e.g., lead and cadmium) also demonstrate reproductive toxicity. …”

Image 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.tif by Xu-Zhe Yu (21509801)

“…Further, only HIF1A was upregulated in the advanced stage of PTC and significantly correlated with the dedifferentiation (all P < 0.05). …”

Table_3_Bacillus velezensis B105-8, a potential and efficient biocontrol agent in control of maize stalk rot caused by Fusarium graminearum.DOCX by Shuang Wang (46453)

“…S-NP activity showed an initial increase with a peak of 20,337 nmol/h/g, followed by a decrease, but activity remained significantly better than control treatment with chemical fungicides. …”

Data_Sheet_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Image 9_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…Consequently, mice treated with CCT007093 exhibited significantly reduced serum HBsAg levels compared to vehicle-treated mice. …”

Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Image 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.pdf by Zhanyi Yang (5142182)

“…In hepatocytes, MORC4 knockdown significantly elevated total TC/TG levels, as well as enhanced lipid accumulation. …”

Table_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.DOCX by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Table 2_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.docx by Ru Chen (186859)

“…Regionally, both mortality rates and DALYs significantly decrease with increasing SDI. Sub-Saharan Africa and South Asia have high levels of incidence and prevalence. …”

Image1_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…Overexpression of FGFR1 in BEAS-2B cells significantly enhanced cell proliferation and stimulated NF-ĸB transcriptional activity in HERK-293T cells. …”

Table 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.xlsx by Zhanyi Yang (5142182)

“…In hepatocytes, MORC4 knockdown significantly elevated total TC/TG levels, as well as enhanced lipid accumulation. …”

Supplementary Material for: Evolution of growth following anti-TNF-α therapy in paediatric Crohn’s disease: data from the Swiss IBD Cohort Study by figshare admin karger (2628495)

“…Height velocity z-scores showed a significant increase across both genders. Factors contributing to a decreased height z-score included male sex, age 10 and below at diagnosis, a concomitant corticosteroid treatment and a top-down treatment strategy. …”

Figure 3 from Mucosal Microbiome Markers of Complete Pathologic Response to Neoadjuvant Therapy in Rectal Carcinoma by Ibrahim M. Abukhiran (21244578)

“…<p>Mucosal microbiome α diversity is decreased with high radiation injury histology score. …”

Supplementary file 1_Global trends in childhood urinary tract infections, 1990–2021: results from the GBD study.docx by Xiepeng Zuo (22308208)

“…Notably, childhood UTIs burden demonstrated significant associations with regional socioeconomic development and environmental conditions. …”

Data (NICU - AMR Data set). by Biniyam Tedla Mamo (20598461)

“…More than half neonatal sepsis was caused by MDR organisms and associated with significant poor treatment outcomes. high prevalence of MDR-gram-negative bacteremia is alarming and highlights the need for the implementation of routine surveillance and infection control measures to decrease morbidity and mortality and to combat the development of antimicrobial resistance.…”

Table 1_The global burden of childhood diarrhea and its epidemiological characteristics from 1990 to 2021.doc by Hai-Yan Zhu (17595684)

“…The ASPR is mostly concentrated in children aged 10–14 years old, among which the ASPR of children under 5 years old has the most significant decline, from 3,138.81 per 100,000 people (95% UI: 2,749.19–3,557.51) in 1,990–885.07 per 100,000 people (95% UI: 755.93–1,029.39), a decrease of 71%. …”

Patient characteristic. by Biniyam Tedla Mamo (20598461)

“…More than half neonatal sepsis was caused by MDR organisms and associated with significant poor treatment outcomes. high prevalence of MDR-gram-negative bacteremia is alarming and highlights the need for the implementation of routine surveillance and infection control measures to decrease morbidity and mortality and to combat the development of antimicrobial resistance.…”

Laboratory data. by Biniyam Tedla Mamo (20598461)

“…More than half neonatal sepsis was caused by MDR organisms and associated with significant poor treatment outcomes. high prevalence of MDR-gram-negative bacteremia is alarming and highlights the need for the implementation of routine surveillance and infection control measures to decrease morbidity and mortality and to combat the development of antimicrobial resistance.…”

Supplementary Material for: Conversion Ability of Immunotherapy in Hepatocellular Carcinoma: Insights from the International Converse Study by figshare admin karger (2628495)

“…The primary endpoint was the curative conversion rate, differentiating potential conversion (PC) - when objective response (OR) resulted in a consistent decrease in tumour burden and alpha-fetoprotein levels - from actual conversion (AC), when OR led to curative treatment. …”