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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
linear decrease » linear increase (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
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19561
Image 1_REDD1 attenuates cholestatic liver fibrosis and suppresses PI3K/AKT/mTOR pathway.jpg
Published 2025“…</p>Results<p>RNA sequencing revealed REDD1 was significantly upregulated in BDL-induced fibrotic liver tissue. …”
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19562
DataSheet10_Refining dual RNA-seq mapping: sequential and combined approaches in host-parasitic plant dynamics.csv
Published 2024“…The evolutionary distance between parasitic and host plants did not significantly impact the accuracy of read assignment to their respective genomes since enough polymorphisms were present to ensure reliable differentiation. …”
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19563
Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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19564
Table_1_Tick cysteine protease inhibitors suppress immune responses in mannan-induced psoriasis-like inflammation.docx
Published 2025“…Tick protease inhibitors have significantly decreased psoriasis symptoms and disease manifestations but had differential effects on inflammatory responses and immune cell populations, suggesting different modes of action of these inhibitors on psoriasis-like inflammation. …”
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19565
Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes
Published 2025“…In the MSC-ex group, the expression of IL-1β, TNF-α and MCP-1 decreased, and expression of IGF-1 and TIMP-2 increased. …”
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19566
Image 1_The impact of tumor burden score on prognosis in patients after radical resection of hepatocellular carcinoma: a single-center retrospective study.tif
Published 2024“…</p>Conclusion<p>In patients undergoing radical resection for HCC, higher TBS was significantly related to shorter OS and RFS.</p>…”
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19567
Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx
Published 2024“…In addition, DBM decreased the accumulation of microglia and downregulated neuroinflammation in the hippocampus and amygdala of 5×FAD mice.…”
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19568
Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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19569
Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif
Published 2024“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”
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19570
Data Sheet 15_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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19571
Image 5_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg
Published 2025“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”
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19572
Effects of Feed Enriched with Freshwater Fish Oil on the Nutritional Profile and Growth Performance of Asian Redtail Catfish (Hemibagrus nemurus) Fry
Published 2024“…The results showed that feed enrichment with FFO significantly affected the composition of fatty acids, amino acids, growth performance, and survival (p<0.05). …”
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19573
Table 2_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.xlsx
Published 2025“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”
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19574
DataSheet1_Case report: Comprehensive clinical, pathological and genetic investigations to decipher the background of cyclic thrombocytopenia.pdf
Published 2024“…Flow cytometric assessment of the platelets revealed large number of immature platelets and decreased expression of glycoprotein IIb and IIIa at platelet zenith. …”
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19575
DataSheet1_Type I-conventional dendritic cells support the progression of multiple myeloma in the bone marrow.docx
Published 2024“…Consequently, the frequencies of exhausted CD8 T cells and regulatory T cells significantly decreased in the bone marrow of cDC1-depleted mice.…”
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19576
Table 1_The RNA-binding protein ProQ directly binds and regulates virulence genes in enterohemorrhagic Escherichia coli O157:H7.docx
Published 2025“…We found that deletion of proQ significantly enhanced cell adherence ability of EHEC and led to upregulation of the locus of enterocyte effacement (LEE) pathogenicity island. …”
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19577
Image 2_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg
Published 2025“…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…”
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19578
Table 4_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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19579
Data Sheet 1_Neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; systemic immune-inflammatory Index: inflammatory indicators of cognitive impairment in schizophrenia pati...
Published 2025“…NLR, PLR, and SII were significantly inversely correlated with the total score of cognitive function and scores across all aspects, whereas lymphocytes were considerably positively correlated. …”
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19580
Table 3_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”