HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2 by Kejian Zhou (22557101)

“…</p> <p>Fourteen days post-MCAO, Col003 treatment significantly decreased cerebral infarct volume and enhanced neurological function scores in rats. …”

Introducing TRECEY: An algorithm for tremor compensation using eye-tracking during multimedia remote controller operation in Parkinson’s disease (PD) by Ritam Ghosh (17122404)

“…These tremors cause significant difficulty in performing everyday activities such as buttoning shirts, using a fork, writing, and operating a computer mouse or television remote making the patients reliant on their caregivers. …”

DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf by Seungchan An (6256061)

“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”

Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx by Seungchan An (6256061)

“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”

Effect of Warmed Ropivacaine Versus Room Temperature Ropivacaine Performing Spinal Anesthesia on Recovery of Lower Limb Muscle Strength Following Total Knee or Hip Replacement: A P... by erfei zhang (21529940)

“…The onset time of sensory and motor nerve block were significantly decreased by warmed ropivacaine compared to room temperature ropivacaine. …”

Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy by Ya-yin Tan (21448519)

“…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …”

Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx by Chunyu Yao (13559263)

“…</p>Results and discussion<p>We established three dosage groups (2.5 × 10⁸, 5 × 10⁸, and 1.5 × 10⁹ CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …”

Supporting information Abou-Kandil et al. by Olaf Kniemeyer (8561361)

“…Deletion of <i>rtaA</i> did not significantly change the ergosterol content of <i>A. fumigatus</i>, but decreased fluorescence intensity of the sterol-binding stain filipin. …”

Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf by Rong Wu (152554)

“…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…”

Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif by Yaqi Cui (10798865)

“…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …”

Differences in lesion development of slow- and fast-growing meat-type chickens after experimental challenge with <i>Enterococcus cecorum</i> by Amanda Rosenbaum (19074302)

“…Additionally, circulating monocytes were increased and heterophil/lymphocyte (H/L) ratios were decreased in SG chickens compared to FG chickens. We may speculate that SG chickens were less affected by the EC-associated disease due to a more efficient innate immune response and may more vigorously control extra-intestinal colonization after translocation from the intestine. …”

Data Sheet 1_Freshwater transport variation through Fram and Davis Strait influenced by atmospheric circulation.pdf by Jinlong Zhang (175134)

“…The research findings reveal that over the past four decades, the FWT through the straits has not exhibited the anticipated continuous growth. Instead, we observed distinct temporal shifts in regional freshwater export patterns: The FWT in Fram Strait experienced significant increase prior to the 21st century (trend of 10.14 mSv/10yr during 1980-2000), whereas the FWT in Davis Strait showed acceleration after 2000 (trend of 13.69 mSv/10yr). …”

Mendelian randomization analysis revealed that albuminuria is the key factor affecting socioeconomic status in CKD patients by Jianbo Qing (12864269)

“…In the multivariable MR analysis, both CKD (OR = 0.867, 95% CI: 0.786–0.957, <i>p</i> = 0.0045) and eGFR (OR = 0.065, 95% CI: 0.010–0.437, <i>p</i> = 0.0049) exhibited significant effects on income. This study underscores that higher albuminuria levels in CKD patients are associated with decreased income and emphasizes the importance of effective management and treatment of albuminuria in CKD patients to mitigate both social and personal economic burdens.…”

Supplementary Material for: The role of neutrophils in venous thrombosis in primary membranous nephropathy by figshare admin karger (2628495)

“…In animal experiments, the plasma cfDNA levels elevated significantly after IVC stenosis in PHN rats, and GSK484 decreased the plasma cfDNA levels in PHN rats with IVC stenosis. 4 hours after IVC stenosis surgery, thrombi formed in PHN rats were both longer and heavier compared to those observed in control rats, and GSK484 administration significantly inhibits the thrombus formation in PHN rats. …”

Image 2_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif by Xinxiao Gao (21717197)

“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”

Image 1_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif by Xinxiao Gao (21717197)

“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”

SPEED-ACCURACY TRADE-OFF PARADIGM IN COOPERATIVE TRANSPORT OF ANTS by N FC (19866297)

“…Regarding the efficiency estimators, we found that the consensus time decreases as the level of competition increases. …”

<b>PathoBiocheModelling to manage Unknowns in Neurodevelopmental Cofactor Disorders</b> by Yuliya Buinitskaya (8680986)

“…Since the vitamin levels including FAD were normal, a genetic cause was suspected. Moreover, we also found decreased activity of some other FAD dependent enzymes such as Aconitase. …”

<i>Hif-1α</i> ablation reduces the efficiency of NeuroD1 gene-based therapy and aggravates the brain damage following ischemic stroke by Nashwa Amin (11242159)

“…Meanwhile, <i>Hif-1α</i> ablation significantly decreased the efficiency of NeuroD1 gene-based therapy.…”

Data Sheet 1_Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway.pdf by Zulipikaer Wusiman (20852138)

“…In addition, we found that GA decreased ROS and MDA levels and increased the expression of GSH, CAT and T-SOD. …”