بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
greater decrease » greatest decrease (توسيع البحث), greater increase (توسيع البحث), greater disease (توسيع البحث)
increase » increased (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
greater decrease » greatest decrease (توسيع البحث), greater increase (توسيع البحث), greater disease (توسيع البحث)
increase » increased (توسيع البحث)
-
20841
Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg
منشور في 2025"…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
-
20842
Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
منشور في 2025"…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …"
-
20843
Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc...
منشور في 2025"…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…"
-
20844
Table 6_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
منشور في 2025"…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"
-
20845
Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls...
منشور في 2024"…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …"
-
20846
Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx
منشور في 2025"…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p<sub>trend</sub><0.01). …"
-
20847
Table 2_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
منشور في 2025"…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"
-
20848
Global Climate Synergies: Coordinated Application of Urban, Technological, and Ecosystem Solutions in the Planet’s Strategic Regions / <b>Sinergias Climáticas Globales: Aplicación...
منشور في 2025"…Simultaneous action in these strategic zones can significantly contribute to reducing local temperatures, stabilizing atmospheric patterns, and mitigating global warming.…"
-
20849
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
منشور في 2025"…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …"
-
20850
<b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de...
منشور في 2025"…Large thermal masses such as roofs, asphalt roads, and concrete structures store significant amounts of solar radiation during the day (up to 1200–1600 MJ/m²). …"
-
20851
DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx
منشور في 2025"…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…"
-
20852
Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
منشور في 2025"…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
-
20853
Cued-attention is mediated by a cholinergic HDB to SAC circuit.
منشور في 2025"…Inset denotes glomeruli with significant changes with SAC inhibition. Yellow: increased, dark grey: decreased, light grey: unchanged. …"
-
20854
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi...
منشور في 2025"…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I<sup>2</sup> = 23%) in patients with SGLT-2i treatment compared with non-users. …"
-
20855
Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study
منشور في 2024"…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …"
-
20856
Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus.
منشور في 2025"…Color represents statistical significance after multiple testing adjustments. <b>E)</b> Signed bar plot displaying significant co-expression changes of the identified 7 gene modules in hippocampal excitatory neurons in stimulation vs ambient TsD65n mice. …"
-
20857
Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
منشور في 2025"…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
-
20858
S1 File -
منشور في 2024"…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …"
-
20859
PTEN KD induces EMT in epithelial CRC cells.
منشور في 2024"…All significant comparisons are shown. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, **** P ≤ 0.0001.…"
-
20860
Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor...
منشور في 2025"…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …"