Showing 19,821 - 19,840 results of 21,342 for search '(( significant decrease decrease ) OR ( significantly ((longer decrease) OR (linear decrease)) ))', query time: 0.71s Refine Results
  1. 19821

    Image 12_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

    Published 2025
    “…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
  2. 19822
  3. 19823

    Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx by Wenqiao Jia (12356306)

    Published 2025
    “…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca<sup>2+</sup>/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…”
  4. 19824

    Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx by Shenglan He (7641308)

    Published 2025
    “…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”
  5. 19825

    Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

    Published 2025
    “…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
  6. 19826

    Image 1_Immunomodulatory effects of probiotic Lactobacillus brevis ZG2488 on SARS-CoV-2 vaccine responses in mice.tif by Mengshan Chen (14303892)

    Published 2025
    “…</p>Results<p>ZG2488 intervention significantly enhanced local mucosal humoral immunity in the respiratory tract (increased SARS-CoV-2-specific IgG in BALF) and systemic Th1 cellular immunity (increased IFN-γ secretion by splenocytes). …”
  7. 19827

    S1 File - by Shi-jie Wang (18569781)

    Published 2025
    “…The results showed that muscle TOR knockdown and endurance exercise significantly increased the climbing speed, climbing endurance, the expression of autophagy related gene 2(ATG2), silent information regulator 2(SIR2), and pparγ coactivator 1(PGC-1α) genes, and superoxide dismutases(SOD) activity, but it decreased the expression of the TOR gene and reactive oxygen species(ROS) level, and it protected the myofibrillar fibers and mitochondria of skeletal muscle in Drosophila on a high-salt diet. …”
  8. 19828

    Image 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

    Published 2025
    “…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”
  9. 19829

    YOLOv8n structure diagram. by Yaojun Zhang (389482)

    Published 2025
    “…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
  10. 19830

    Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx by Demos Kynigopoulos (12420457)

    Published 2025
    “…</p>Results<p>Alirocumab significantly improved spatial working memory, restored hippocampal long-term potentiation, and normalized synaptophysin expression. …”
  11. 19831

    Supplementary file 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.docx by You Yu (2102071)

    Published 2025
    “…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”
  12. 19832

    Table 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx by M. Elakkya (21760439)

    Published 2025
    “…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
  13. 19833

    DataSheet9_Refining dual RNA-seq mapping: sequential and combined approaches in host-parasitic plant dynamics.csv by Carmine Fruggiero (20143830)

    Published 2024
    “…The evolutionary distance between parasitic and host plants did not significantly impact the accuracy of read assignment to their respective genomes since enough polymorphisms were present to ensure reliable differentiation. …”
  14. 19834

    Image 4_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

    Published 2025
    “…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”
  15. 19835

    DataSheet_1_RETRACTED: Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia.docx by Youfeng Zhu (2460811)

    Published 2024
    “…Depletion of macrophages protected against lung epithelial cells and significantly decreased MMP9, MMP19, FTH, and FTL expression levels and increased GPX4 expression levels, while partially reversing the changes in macrophage. …”
  16. 19836

    Table_4_Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites.DOCX by Yexun Zhou (11711813)

    Published 2025
    “…We discovered that TAX increased sperm motility significantly in Duroc boars by the elevation of the protein levels such as ZAG, PKA, CatSper, and p-ERK for sperm quality. …”
  17. 19837

    Image 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

    Published 2025
    “…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
  18. 19838

    Dust deposition, escape data table. by Yuxuan Liu (349237)

    Published 2025
    “…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”
  19. 19839

    Table 1_Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.docx by Hua-Liang Li (20812799)

    Published 2025
    “…</p>Results<p>Compared to healthy controls, medication-naïve patients with BSP exhibited significantly increased ALFF in the bilateral putamen and left premotor cortex and decreased ALFF in the bilateral thalamus (p < 0.05, threshold-free cluster enhancement with family-wise error correction for multiple comparisons). …”
  20. 19840

    raw data for GCB paper.xlsx by Dongming Wang (21443882)

    Published 2025
    “…</p><p dir="ltr">Decades of Free Air CO<sub>2</sub> Enrichment (FACE) experiments show that projected atmospheric carbon dioxide (CO<sub>2</sub>) increases significantly influence crop systems, impacting food security. …”