Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg حسب Johnny Amer (495285)

"…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"

Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx حسب Ying Zhang (40767)

"…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …"

Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc... حسب Yuanhang Rong (19207540)

"…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…"

Table 6_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx حسب Jianwei Hong (6918776)

"…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"

Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls... حسب Lei Qian (292302)

"…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …"

Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx حسب Christoph Riegler (3554054)

"…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p_trend<0.01). …"

Table 2_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx حسب Jianwei Hong (6918776)

"…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"

Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx حسب Chen-xiao Liu (22750118)

"…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …"

A Locally Linear Dynamic Strategy for Manifold Learning. حسب Weifan Wang (4669081)

"…In contrast to alignment modulation, the change in the spectrum is largely non-selective. exhibits no significant change for both signal-oriented (blue) and noise-oriented (orange) modes. …"

Cued-attention is mediated by a cholinergic HDB to SAC circuit. حسب Rahul Garg (3064578)

"…Inset denotes glomeruli with significant changes with SAC inhibition. Yellow: increased, dark grey: decreased, light grey: unchanged. …"

Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... حسب Yiran Wang (1492303)

"…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I² = 23%) in patients with SGLT-2i treatment compared with non-users. …"

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study حسب Lu Wang (45927)

"…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …"

Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus. حسب Md Rezaul Islam (19649494)

"…Color represents statistical significance after multiple testing adjustments. <b>E)</b> Signed bar plot displaying significant co-expression changes of the identified 7 gene modules in hippocampal excitatory neurons in stimulation vs ambient TsD65n mice. …"

S1 File - حسب Zsófia Tróznai (19923854)

"…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …"

PTEN KD induces EMT in epithelial CRC cells. حسب Ahmed H. Ghobashi (12705573)

"…All significant comparisons are shown. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, **** P ≤ 0.0001.…"

Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor... حسب Ying Feng (151159)

"…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …"

Flowchart of the selection program. حسب Zsófia Tróznai (19923854)

"…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …"

Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX حسب Ji Zeng (4336561)

"…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…"

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... حسب Ying Feng (151159)

"…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …"

Supporting data for "DECODING THE NEUROIMMUNE AXIS OF HEAD AND NECK CANCER TO ENHANCE IMMUNOTHERAPEUTIC OUTCOMES" حسب Ravi Kishan (11263155)

"…Genetic ablation of PTHLH resulted in dysregulation of neurotrophic signaling pathways essential for intra-tumoral innervation, significant reduction in tumor burden, and enhanced antitumor immunity —evidenced by increased CD8+ and CD4+ T cell infiltration, as well as decreased immunosuppressive markers. …"