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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
lower decrease » larger decrease (Expand Search), linear decrease (Expand Search), teer decrease (Expand Search)
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19281
Image 2_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as...
Published 2024“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”
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19282
Table2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19283
Table3_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19284
Table 1_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as...
Published 2024“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”
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19285
Table1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19286
Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19287
Image 3_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as...
Published 2024“…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”
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19288
Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pat...
Published 2025“…</p> <p>Compared to the control group, the model group showed significantly more coughs, which were markedly reduced by LD treatment (<i>p</i> = 0.0083 and <i>p</i> = 0.0117). …”
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19289
Table 1_Associations between gut microbiota and diet composition of three arid-adapted rodent species from the Inner Mongolia grassland.doc
Published 2025“…In contrast, the consumption of animal-based foods significantly decreased microbial diversity. This finding suggests a potential link between the host’s genetic background, dietary composition, and the gut microbiota.…”
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19290
DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF
Published 2024“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”
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19291
Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx
Published 2025“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”
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19292
Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx
Published 2025“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”
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19293
Table 3_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
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19294
Mapping global urban inequality under climate change and its interaction with sustainable development
Published 2025“…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …”
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19295
Image 1_The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells.tif
Published 2025“…E2F1 was identified as an upstream regulator of EIF4EBP1, with knockdown of E2F1 significantly decreasing EIF4EBP1 promoter activity and binding. …”
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19296
Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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19297
Table_2_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls
Published 2025“…We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”
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19298
Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx
Published 2025“…</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …”
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19299
Table_3_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls
Published 2025“…We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”
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19300
Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”