Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model by Gao Xi (22574101)

“…Intra-articular delivery of FGF18 in destabilized medial meniscus (DMM)-induced PTOA mice significantly reduced cartilage erosion and markedly decreased synovial thickening compared to saline-treated controls, with improved cartilage matrix integrity. …”

Supplementary file 1_Colonizable probiotic Lactobacillus paracasei R3 enhances ICI therapy via modulating PBMCs differentiation.docx by Wencan Song (21477434)

“…Our results also showed the rapid adherence of L.p R3 to intestinal epithelial cell membrane, and promoted intestinal epithelial cell expression of mucin mRNA, led to the long maintenance of L.p R3 in colon and cecum in mice. L.p R3 significantly elevated the levels of macrophages, CD4⁺T cells and CD8⁺T cells in PBMCs while simultaneously decreasing the level of programmed cell death protein 1 (PD-1) on the surface of CD4⁺T cells and CD8⁺T cells. …”

Beta Diversity and Differential Abundance Analysis of Gut Microbiota after FVT. by Melany Cervantes-Echeverría (22794116)

“…The blue bars indicate taxa significantly increased, while the red bars indicate taxa significantly decreased in the FVT compared to the control. …”

Image 2_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.jpeg by Xiaoyang Yuan (11216262)

“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”

Image 1_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.jpeg by Xiaoyang Yuan (11216262)

“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”

Data Sheet 1_The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation.docx by Qian Qian (45749)

“…Neutrophil-related markers like IL6, IL8, and neutrophil extracellular traps (NETs) were significantly elevated in this model. Inhibiting neutrophils production significantly improved airway inflammation and lung function. …”

Image 3_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.tif by Xiaoyang Yuan (11216262)

“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein by Xiangchao Jia (21392720)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx by Demet Kartal (20817926)

“…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …”

Datasheet1_Combined endovascular interventions for pulmonary embolism at high altitude in Tibet.zip by Tengyan Yang (19834944)

“…The heart rate (p < 0.05) and respiratory rate (p < 0.001) of all enrolled patients were significantly decreased, and the peripheral capillary oxygen saturation (SpO2) was significantly increased (p < 0.05) after interventions. …”

Low temperature reduces byssus adhesion of highly invasive golden mussels: Influencing mechanisms and antifouling implications by Miaolian Zhang (21974951)

“…Our results showed that low-temperature exposures significantly reduced adhesion rates of golden mussels, primarily by limiting byssus production associated with impaired synthesis and secretion of byssal proteins and decreasing byssus breaking force. …”

Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx by Jessica Alves Freitas (20974076)

“…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”

Areal densities of single targets in the feeding areas of northern and southern resident killer whales. by Burak Saygili (19832062)

“…Prey densities differed significantly between feeding areas, and generally decreased as the fish migrated from west to east towards the Fraser River. …”

All data. by Ke Li (106849)

“…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …”

Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... by Yuanling Yang (22524785)

“…In contrast, 400 μM MT treatment effectively mitigated oxidative damage by coordinated activation of superoxide dismutase (SOD,+14.3%), peroxidase (POD,+21.7%), and catalase (CAT,+11.7%) activities, thereby stabilizing membrane integrity. Furthermore, MT significantly alleviated photoinhibition: F_V/F_M increased by 39%, Y_II and qP rose, and NPQ decreased compared to salt-stressed plants, reflecting enhanced protection of the PSII reaction center and optimized light energy allocation. …”

Raw data for figures and tables in the paper. by Runhai Jiang (19871068)

“…<i>rwandensis</i> could promote the transformation of Pb fractions and a functional change in the soil bacterial community, ultimately decreasing Pb accumulation in the biomass and promoting the development of maize.…”

Data Sheet 1_Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage po... by Maolin Chu (11611507)

“…Furthermore, reducing cellular LXN/Rps3/p53 signaling significantly decreased SASP factors in the culture medium and simultaneously abolished M1-like phenotype macrophage polarization. …”

Method for establishing the multipath adaptive mitigation model considering deformation displacement of monitoring stations by Guo Zihuai (20442074)

“…The comparison between MAMM and the Multipath Hemispherical Model (MHM) indicates that, in the simulated displacement experiments, MHM’s effectiveness in mitigating multipath errors significantly decreases as the actual displacement distance increases, whereas MAMM consistently maintains an improvement rate in positioning precision of over 100%, markedly surpassing that of MHM. …”

Table 1_The impact of digital economy on the supply chain resilience of cross-border healthcare e-commerce.xlsx by Jianyu Liu (313522)

“…The results indicate that the digital economy significantly enhance supply chain resilience, with reduced reliance on foreign trade, increased export technology complexity, and decreased export concentration being key pathways for this improvement. …”

Image3_Effects of polystyrene microplastics on the growth and metabolism of highland barley seedlings based on LC-MS.png by Wenqi Xiao (17657980)

“…Metabolome analysis revealed that the contents of 4 metabolites increased significantly with increasing PS-MPs concentration in positive ionmode, while the contents of 8 metabolites increased significantly with increasing PS-MPs concentration in negative ionmode (P < 0.05), including prunin, dactylorhin E, and schisantherin B. …”