Table 1_Mechanism of action of decitabine in treating acute lymphoblastic leukemia.docx by Xiaohui Gao (308514)

“…Animal experimental results indicated that both DAC and doxorubicin substantially decreased tumor length, width, volume, and mass; however, DAC demonstrated significantly superior efficacy in inhibiting tumor growth compared to doxorubicin.…”

Table1_Local sediment amendment can potentially increase barley yield and reduce the need for phosphorus fertilizer on acidic soils in Kenya.DOCX by Eric Scherwietes (19768551)

“…The Baringo 3% amendment significantly increased soil pH (from 4.7 to 7.0), the available P content (from 0.01 mg g⁻¹ to 0.02 mg g⁻¹) and decreased the Al availability (from 3.03 mg g⁻¹–2.17 mg g⁻¹). …”

Scorpion venom cytolytic peptide Smp43 induces caspase-dependent apoptosis in ovarian carcinoma cell line OVCAR-3 by Salwa I. Hussein (22234753)

“…Additionally, Smp43 significantly increased DNA fragmentation in OVCAR-3 cells and decreased antioxidant parameters. …”

Table 5_Genome-wide identification of the COBRA-like gene family and expression pattern analysis under abiotic stresses of Sorghum bicolor (L.).xls by Shipeng Liu (800573)

“…The tissue-specific expression patterns of SbCBL genes suggest varying expression levels across different organs and tissues in S. bicolor, with SbCBL1, SbCBL5, and SbCBL9 showing significantly higher expression levels in roots. PEG and NaCl treatments significantly affected SbCBL expression levels. …”

Data Sheet 1_Metabolic modulation and multi-species interaction: Lactiplantibacillus plantarum’s impact on Streptococcus mutans-Candida albicans in a mucosal model.pdf by Ting Li (117885)

“…Notably, L. plantarum significantly altered the metabolic landscape of these pathogens, especially under GOS conditions.…”

Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis by weiwei zheng (11880230)

“…Obvious histopathological differences were detected in resistant and susceptible individuals in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing was performed to characterize the changes in intestinal microbial community, in which Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. RNA-seq analysis indicated that 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than 310 in the resistant group, when compared to the control group. …”

Image 1_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif by Lili Deng (152262)

“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”

DataSheet1_Drought stress reduces arbuscular mycorrhizal colonization of Poncirus trifoliata (L.) roots and plant growth promotion via lipid metabolism.docx by Wei Zhang (405)

“…Results indicated that AM fungal inoculation significantly promoted the drought tolerance of P. trifoliata (L.), with the effect size decreasing along with drought severity. …”

Table 4_Effectiveness of an exercise and nutrition intervention for older adults with mild cognitive impairment: an open-label double-arm clinical trial.docx by Moeko Noguchi-Shinohara (564225)

“…</p>Results<p>The MPI score significantly increased by 1.8 in the intervention group and significantly decreased by 1.2 in the nonparticipant groups (p = 0.049).…”

Image 7_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 10_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 1_Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation.png by Xing Han (802860)

“…The diameter and number of cancerous foci were significantly decreased in CRC mice treated with FMT, along with the restoration of the intestinal mucosal structure and the lessening of the gland arrangement disorder. …”

Table 2_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx by Lili Deng (152262)

“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”

Supplementary file 1_The shrub density effect: unraveling vertebrate community dynamics along an aridity gradient in Southern California.docx by Mario Zuliani (18612872)

“…Relatively higher near-surface air temperatures (NSAT) significantly decreased vertebrate observations, richness, and evenness. …”

Table 1_Distinct vaginal microbiome and metabolome profiles in women with preterm delivery following cervical cerclage.docx by Jun Zhang (48506)

“…Vaginal microbiome revealed that the proportion of beneficial bacteria (including Lactobacillus, [Ruminococcus] gnavus group, and Megamonas) significantly decreased in the PTB group, and the proportion of harmful bacteria (including Desulfovibrionaceae, Helicobacter, and Gardnerella) significantly increased, which is strongly related to the biochemical parameters of blood (white blood cells, neutrophils, NLR, and SIRI). …”

Table 1_Integrative analysis of transcriptome and metabolome reveals molecular mechanisms of dynamic change of storage substances during dehydration and drying process in peanuts (... by Jingjing Deng (468275)

“…S3d was the key period during which the content of most of the metabolites changed significantly. The contents of most amino acids(87%) and their derivatives decreased significantly, and most of the lipids(68%), sugars(67%) and flavonoids(87%) accumulated to their peak at S3d. …”

Data Sheet 1_The response regulator CrsR positively regulates ansamitocin P-3 biosynthesis in Actinosynnema pretiosum.docx by Peipei Zhang (1360440)

“…Deletion of the response regulator gene crsR drastically decreased AP-3 production. RNA-seq revealed CrsR’s global regulatory role, significantly altering transcription of primary metabolic genes, especially those in purine metabolism. …”

Image 8_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Data Sheet 1_Water quality and fluorescent dissolved organic matter dynamics of Dhaleshwari River.pdf by Mohammad Mohinuzzaman (18275214)

“…The socioeconomic and ecological significance of the river is highly critical to the locality. …”

The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence by Huimin Chang (21142907)

“…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …”