يعرض 20,761 - 20,780 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly ((lower decrease) OR (we decrease)) ))', وقت الاستعلام: 0.46s تنقيح النتائج
  1. 20761

    Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke حسب Yike Wu (20982007)

    منشور في 2025
    "…Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …"
  2. 20762

    Supplementary file 1_Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021.pdf حسب Li Yang (6520)

    منشور في 2025
    "…</p>Results<p>From 1990 to 2021, The ASR of all-cause DALYs in China decreased by 35.94% overall and by 33.99% among individuals ≥65 years. …"
  3. 20763

    S1 Data - حسب Yumeng Zhang (3115050)

    منشور في 2024
    "…The results of this study suggest that the level of well-being as a whole, as well as in the eastern, central and western regions increased significantly over the period, with an “east-to-west decreasing” distribution in China. …"
  4. 20764

    Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf حسب Qi Dong (119569)

    منشور في 2025
    "…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"
  5. 20765

    Data Sheet 1_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

    منشور في 2025
    "…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"
  6. 20766

    Table 3_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

    منشور في 2025
    "…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"
  7. 20767

    Health Risks of Low-Dose Dietary Exposure to Triphenyl Phosphate and Diphenyl Phosphate in Mice: Insights from the Gut–Liver Axis حسب Jing Cao (287196)

    منشور في 2025
    "…TPHP intake affected the levels of short-chain fatty acids and bile acids in the gut, enhancing the production of 29 medium- and long-chain fatty acids in the liver by 3.72-fold and significantly increasing hepatic lipid and cholesterol levels. …"
  8. 20768

    Supplementary Material for: Quality of Life After Alloplastic vs. Autologous Breast Reconstruction: 'The Influence of Patient Characteristics on Outcomes' حسب Holt-Kedde I.L. (20616542)

    منشور في 2025
    "…Conclusion: This study confirms that even when adjusted for confounders, scores on two QoL sub-scales autologous breast reconstruction patients score significantly higher over time. Although autologous reconstruction remained superior regarding “Satisfaction with Breasts”, scores decreased in autologous reconstruction patients when they were depressed at baseline, underwent radiotherapy, had a history of breast cancer, or faced major complications.…"
  9. 20769

    Shape error manual calculation process. حسب Zhe Hu (787283)

    منشور في 2025
    "…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…"
  10. 20770

    Outcomes of Corticosteroids Combined with 15 Mg/Week Methotrexate as Initial Treatment for Acute Vogt-Koyanagi-Harada Disease حسب Yao Lu (185912)

    منشور في 2025
    "…All the eyes had retinal reattachment and the choroidal thickness significantly decreased. Sun-set glow fundus was identified in 18 eyes (23.1%). …"
  11. 20771

    Data Sheet 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf... حسب Yuanbing Zhu (20538638)

    منشور في 2025
    "…Differential gene expression and immune infiltration analysis showed that upstream transcription factors, including Forkhead box P3 (FOXP3), were significantly disrupted. In vitro cytology experiments, the results indicate that SIRT1 is activated in LPS induced inflammation, subsequently perturbing the Treg/Th17 immune balance axis. …"
  12. 20772

    Data Sheet 1_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.pdf حسب Mingjia Lu (21593324)

    منشور في 2025
    "…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …"
  13. 20773

    Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip حسب Yonghu Chen (2040136)

    منشور في 2025
    "…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …"
  14. 20774

    Table 5_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

    منشور في 2025
    "…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"
  15. 20775

    Table 2_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.docx حسب Mingjia Lu (21593324)

    منشور في 2025
    "…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …"
  16. 20776

    Supplementary file 2_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx حسب Jinghuai Ni (21023477)

    منشور في 2025
    "…In addition, SC treatment markedly increased Runx2, Osx, Alp, and Cx3cr1 while decreasing adipogenic genes like PPARγ and C/EBPα in the bone tissue of OVX mice and BMMSCs. …"
  17. 20777

    U-wave estimates versus R-matrix noise variance. حسب Zhe Hu (787283)

    منشور في 2025
    "…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…"
  18. 20778

    Table 1_WTAP modulates macrophage polarization in rheumatoid arthritis by targeting exosomal circ-CBLB via m6A modification.docx حسب Dawei Yan (193244)

    منشور في 2025
    "…Functional experiments demonstrated that WTAP overexpression decreased exosomal circ-CBLB levels and promoted macrophage polarization toward the pro-inflammatory M1 phenotype, which was reversed by m<sup>6</sup>A modification site mutation.…"
  19. 20779

    Image 2_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg حسب Chenchao Zou (22768010)

    منشور في 2025
    "…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …"
  20. 20780

    Sliding window process. حسب Zhe Hu (787283)

    منشور في 2025
    "…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…"