DataSheet1_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Supplementary Material for: Yoga Asana Increases Pre-Frontal Cortex Activity and Reduces Resting State Functional Connectivity by figshare admin karger (2628495)

“…Furthermore, analysis of short-term changes in resting-state functional connectivity (rsFC) revealed a significant decrease, primarily in the left medial prefrontal cortex (PFC), a key region of the default mode network (DMN), an area known to exhibit heightened activity in individuals suffering from depression and anxiety Conclusion: This study provides neurological insight into the effects of yoga asana and supports fNIRS for assessing movement-based practices in real-world settings.…”

Table 2_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In the syncytiotrophoblast (SCT), the primary maternal-fetal barrier, preeclampsia was associated with a significant downregulation of LDLR and cholesterol biosynthesis genes (OR = 4.991, p = 6.30e−04). …”

Table 1_fNIRS, EEG, ECG, and GSR reveal an effect of complex, dynamically changing environments on cognitive load, affective state, and performance, but not physiological stress.xl... by Henrikke Dybvik (11492599)

“…Participants performed significantly better in Easy, followed by Ramp and Hard. …”

Table 1_Global burden of tuberculosis attributable to diet low in whole grains from 1990 to 2021, with projection to 2045.pdf by Xiaoning Lu (206322)

“…</p>Results<p>In 2021, TB-DLWG accounted for 177,303.55 DALYs globally, representing an 8% decrease from 1990. The number of deaths was 5,539.13, a 12% reduction. …”

Image_1_Education and metabolic syndrome: a Mendelian randomization study.pdf by Dong Liu (115204)

“…</p>Conclusion<p>The findings of this study suggest that education can decrease the incidence of MetS.</p>…”

Mitochondrial electron transport chain disruption and oxidative stress in lipopolysaccharide-induced cardiac dysfunction in rats and mice by Agda Aline Pereira de Sousa (21369738)

“…In a more acute Langendorff-perfused rat hearts, LPS infusion (0.5 μg/mL) induced a significant elevation in left ventricular end-diastolic pressure and a decrease in left ventricular developed pressure. …”

Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

“…The efficacy evidence of CAs supported by single-arm trials demonstrated statistically significant variances in indication and drug types. …”

The state variable descriptions of the model. by Sisay Fikadu Jaleta (20912783)

“…<div><p>Malaria remains a significant global health challenge, particularly in developing countries. …”

Video 1_Progressive encephalomyelitis with rigidity and myoclonus after thymectomy in a woman with myasthenia gravis.mp4 by Lixia Qin (3358520)

“…The patient was treated with intravenous methylprednisolone, oral clonazepam, and tacrolimus, which resulted in significant clinical improvement. A 2-year follow-up demonstrated sustained recovery, accompanied by a decrease in GAD65 antibody titers. …”

Image 1_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…Although PLK1 inhibitors have emerged as promising therapeutic agents for cancer, their use has been linked to significant anemia in a subset of patients, yet the underlying mechanisms remain poorly understood. …”

Data Sheet 1_Enhanced computerized cognitive remediation therapy improved cognitive function, negative symptoms, and GDNF in male long-term inpatients with schizophrenia.zip by Peiyun Zhang (4484194)

“…Objective<p>Negative and cognitive symptoms present significant challenges in patients with schizophrenia, and cognitive remediation is a promising approach to alleviate these symptoms. …”

Image 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.tiff by Junxian Hu (8158044)

“…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. This was followed by the depolymerization of focal adhesion (FA) complexes, primarily consisting of FAK and integrin β1, which resulted in an increase in collagen type II (Col II) and a decrease in collagen type I (Col I). …”

Supplementary Material for: Dynamics of RTEL1 helicase in meiotic cells: spatiotemporal distribution during prophase I in the rat Rattus norvegicus by figshare admin karger (2628495)

“…As meiosis progresses from early pachytene to diplotene, the significant decrease in RTEL1 and RPA signals underscores their predominant involvement in early prophase I. …”

Data from: Leveraging historical trials to predict Fusarium head blight resistance in spring wheat breeding programs by Charlotte Brault (22078544)

“…Predicting unrelated populations led to a significant decrease in accuracy but with encouraging values for some traits and populations. …”

DataSheet2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Data Sheet 1_Adult-onset hypothyroidism induces granulosa cell apoptosis and affects ovarian follicle development in rats.docx by Shuyue Li (14585343)

“…</p>Results<p>Our results showed that, in addition to a decrease in thyroid hormones, the body weight was significantly reduced, while the estrus cycle was prolonged in the hypothyroidism group. …”

Supplementary file 1_Active fungal infections alter the respiratory microbiome profiles of Mayo Clinic Arizona patients.zip by Daniel R. Kollath (18134608)

“…Patients with disseminated coccidioidomycosis showed evidence of extreme dysbiosis in the lung microbiome with a significant overabundance of Malassezia and Bacilli. …”

Datasheet1_Analysis of blood metabolite characteristics at birth in preterm infants with bronchopulmonary dysplasia: an observational cohort study.pdf by Yanping Guo (2467576)

“…In the GA 24⁺⁴–27⁺⁶ weeks subgroup, we observed a significant decrease in histidine levels and the ornithine/citrulline ratio in the BPD group. …”

Image 1_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”