Data Sheet 1_Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway.docx by Yumei Rong (11589031)

“…Mechanism studies demonstrated that LD₄-PDT could inhibit the NF-κB signaling pathway, downregulated the expression of the inflammatory factors’ tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and myeloperoxidase (MPO), increased the contents of glutathione (GSH) and superoxide dismutase (SOD) and decreased the content of malondialdehyde (MDA). Additionally, analysis of gut microbiota revealed that LD₄-PDT treatment could decrease the abundance of the Proteobacteria phylum in fecal samples, while no significant differences were observed in the Firmicutes, Bacteroidetes, or Actinobacteria phyla among the three groups using 16S rRNA analysis.…”

List of abbreviations used in this paper. by Liuchuang Wei (19273099)

“…<div><p>Postural Orthostatic Tachycardia Syndrome is characterized by an excessive increase in heart rate during postural changes without significant blood pressure alterations, often accompanied by symptoms such as dizziness, fatigue, and palpitations. …”

Comparative analysis of functional group effects on CO₂, CH₄, CO, and N₂ adsorption in UiO-66 and its derivatives by Prudhviraj Medikonda (20561356)

“…The selectivity of CO₂ over CH₄, CO, and N₂ showed that introducing larger and more complex functional groups caused a sudden decrease in selectivity with increasing temperature; this difference was more significant at lower temperatures and negligible at higher temperatures.…”

Image 1_Integrated microbiome and metabolomics analysis reveals the alleviating effect of Pediococcus acidilactici on colitis.pdf by Lulu Wu (7508612)

“…Microbiome analysis showed that colitis could cause a significant decrease in the gut microbial diversity and abundance, but Pediococcus acidilactici administration could restore the microbial index to the control level. …”

Data Sheet 1_Unveiling spatiotemporal evolution and driving factors of ecosystem service value: interpretable HGB-SHAP machine learning model.docx by Xiangming Xu (420946)

“…The ESV exhibited a slight increase in two counties, while it demonstrated a decrease in the remaining 16 counties at the county scale. …”

Table2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Estimation of the CO and CBF. by Liuchuang Wei (19273099)

“…<div><p>Postural Orthostatic Tachycardia Syndrome is characterized by an excessive increase in heart rate during postural changes without significant blood pressure alterations, often accompanied by symptoms such as dizziness, fatigue, and palpitations. …”

Table 2_Ribosomes binding to TAS transcripts buffer ta-siRNA biogenesis in Arabidopsis thaliana.xlsx by Han Wang (254423)

“…In the two-hit model, deletion of ribosome-binding regions resulted in a decrease in the abundance of intact TAS3 transcripts but did not significantly affect ta-siRNAs production or the efficiency of miRNA-guided cleavage. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…All patients achieved stable disease; however, a significant reduction in bone marrow blast percentage after one to two cycles of treatment was observed in two patients, which correlated with a decrease in FLT3-ITD allelic ratio and variant allele frequency of co-occurring mutations (e.g., NPM1 and DNMT3A). …”

VCC-induced pro-inflammatory response generation in BMDMs is dependent on TLR2, TLR4 as well as TLR1. by Shraddha Gandhi (21001590)

“…<p>Significant decrease in the VCC-mediated IL-6 production in BMDMs from TLR2^-/- (A-B), C3H/HeJ (A-B), and TLR1^-/- (C-D) mice, as compared to that in BMDMs from the wild type (WT) mice. …”

Table 1_Apigenin protects ischemic stroke by regulating intestinal microbiota homeostasis, regulates brain metabolic profile.xlsx by Jinjian Li (1651954)

“…</p>Results<p>The intervention with apigenin resulted in significant alterations in the intestinal flora, characterized by an increase in the abundance of probiotic species and a decrease in harmful flora, alongside notable changes in brain metabolite profiles. …”

Data Sheet 1_Numerical modeling of the influence of tidal flats on estuaries: the case of the Guadalquivir estuary, SW of the Iberian Peninsula.docx by Pablo Muñoz-López (21603905)

“…</p>Results<p>The most significant changes in the implementation of tidal flats, primarily local in nature, occur near them, extending asymmetrically a few kilometers along the estuary. …”

Table 4_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In the syncytiotrophoblast (SCT), the primary maternal-fetal barrier, preeclampsia was associated with a significant downregulation of LDLR and cholesterol biosynthesis genes (OR = 4.991, p = 6.30e−04). …”

Hypoxia-induced pulmonary remodeling. by Yuko Shirota (4351867)

“…Group1 mice showed a significant decrease in normal but increase in fully remodeled arterial walls. …”

Strategy parameters across development for female mice in set size = 2 and set size = 4 from winning computational model. by Juliana Chase (20469427)

“…However, female mice had a significant decrease in parameter S1 “Inappropriate Lose-Shift” in set size = 4 (H: <i>p</i> = 0.04) with a trend in a similar direction in set size = 2 (C: <i>p</i> = 0.08).…”

Table3_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

None - by Sisay Fikadu Jaleta (20912783)

“…<div><p>Malaria remains a significant global health challenge, particularly in developing countries. …”

Supplementary Material for: Global, regional, and national epidemiology of Idiopathic Childhood Epilepsy from 1990 to 2021 by figshare admin karger (2628495)

“…Regionally, Southern Latin America saw the largest increase in incidence (EAPC, 0.49), and Eastern Europe observed the most significant mortality decrease (EAPC, -4.65). Ecuador reported the highest incidence rate, Tajikistan the highest mortality, and Zambia the highest DALYs in 2021. …”

Image 2_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg by Shunji Yamada (5543327)

“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”

Table 2_Pandemic predisposing influence for feline lower urinary disorders.xlsx by Carolina C. L. Paulino (21546620)

“…The DP group demonstrated a statistically significant decrease in relapses (p < 0.001) and mortality (p < 0.05) compared to the BP group. …”