Data Sheet 3_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.csv حسب Po-Chun Liu (676035)

"…Additionally, we identified an increase in the ARGORNPROST-PWY pathway (L-arginine degradation, q = 0.003) and a decrease in the PWY-6478 pathway (GDP-D-glycero-α-D-manno-heptose biosynthesis, q = 0.015) in MSA patients compared with HCs.…"

Supplementary file 1_The interaction between obesity and sex alters the response to house dust mite in an experimental model of allergic lung inflammation.docx حسب Amanda Santos-Cavalcante (22288645)

"…Additionally, it has been demonstrated that obesity is a significant predisposing factor for asthma, particularly among women. …"

Table_4_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc حسب Sofia Priyadarsani Das (17830028)

"…The diet containing L. acidophilus at 1 × 10⁷ CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …"

Data Sheet 1_Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microb... حسب Mujeeb Ur Rahman (20445245)

"…Introduction<p>Pneumonia continues to be a significant infectious disease, marked by ongoing lung inflammation, breathing difficulties, and high mortality rates, especially among young children in low-income nations.…"

Image 3_Pharmacokinetics of cannabidiol and its two main phase I metabolites in Connemara ponies.tiff حسب Kata Wermer (21614717)

"…</p>Results<p>The CBD oil was well-tolerated, with no side effects. A significant decrease in heart rate was observed after 24 h. …"

Table 4_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx حسب Inês Carvalho (59935)

"…</p>Results<p>While higher methionine intake reduced hemoglobin levels, no other significant changes in the immune status were observed. …"

Table 1_Muscle quality index and hyperuricemia: adipose tissue as a mediator.docx حسب Ya Shao (16975896)

"…Each one-unit increment in MQI corresponded to a 50% decrease in the odds of hyperuricemia (OR: 0.50, 95% CI: 0.43–0.57). …"

Table 1_Burden of malignant neoplasm of bone and articular cartilage from 1990 to 2021 and its predictions to 2030 in China compared with world.docx حسب Cheng Chen (136164)

"…The burden prediction for MNBAC to 2030 showed that China would experience a more significant drop in incidence and mortality rates for MNBAC, along with a decrease in the incidence and mortality cases.…"

Image 9_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... حسب Changmei Wu (22776269)

"…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …"

Image 3_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg حسب Bingtao Hu (16784702)

"…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …"

Image 2_Allergen immunotherapy using recombinant Culicoides allergens improves clinical signs of equine insect bite hypersensitivity.tif حسب Anneli Graner (19759464)

"…</p>Results<p>In the first treatment year, the decrease in average IBH lesion score was significantly larger in the AIT compared to the placebo group, with 67% of the AIT group and 25% of the placebo horses reaching >50% improvement of the average IBH lesion score. …"

Image 2_Pharmacokinetics of cannabidiol and its two main phase I metabolites in Connemara ponies.tiff حسب Kata Wermer (21614717)

"…</p>Results<p>The CBD oil was well-tolerated, with no side effects. A significant decrease in heart rate was observed after 24 h. …"

Datasheet1_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi... حسب Lucie Hejnova (19676323)

"…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …"

Table 1_Impact of repeated in-vitro bacterial culture on virulence and antibiotic resistance characteristics: a study of Gram-positive and Gram-negative fish pathogens.docx حسب Angana Bag (21398267)

"…The results revealed a significant decrease in the virulence of Gram-positive pathogens. …"

Image 1_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... حسب Changmei Wu (22776269)

"…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …"

Data Sheet 1_In vivo and in vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment.pdf حسب Abdulrahman Johor (21265181)

"…In vivo, the histological study indicated a decrease in tumor size and number following treatment with cisplatin and BM-MSCs. …"

Image1_Survey of in vitro fertilization add-ons in Japan (Izanami project).tif حسب N. Shionoya (19815414)

"…A positive correlation of the adoption rate and an inverse correlation of the cost with the evidence level of the IVF add-on treatment were observed (not significant). Outpatient clinics, defined as medical facilities with no beds, had a significantly higher adoption rate (Amber, 65.7%; Red, 52.0%) of add-ons than other facilities, regardless of the evidence rating, although the costs were similar across all site attributes.…"

Table3_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studies.x... حسب Lucie Hejnova (19676323)

"…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …"

Table2_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx حسب Guangli Xia (19834830)

"…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …"

Supplementary file 2_Longitudinal analysis of coal workers’ pneumoconiosis using enhanced resolution-computed tomography images: unveiling patterns in lung structure, function, and... حسب Ngan-Khanh Chau (17437641)

"…</p>Results<p>The study identified significant airway changes in angles, diameters, and geometry, with a decrease in normal lung tissue in the right upper lobe. …"