Data Sheet 1_Luteolin induces apoptosis in Philadelphia chromosome-positive acute lymphoblastic leukemia cell by regulating the PI3K/AKT signaling pathway.zip by Qin Ren (150436)

“…Luteolin (LUT), a natural flavonoid compound, has demonstrated significant anticancer activity. However, its mechanism of action in the context of Ph + ALL remains poorly understood. …”

Figure 1 from Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma by Edgar Gonzalez-Kozlova (18366814)

“…The −log₁₀ (<i>P</i> value) is represented by the size of the circles, indicating statistical significance as the circles increase. <b>D,</b> Line and boxplot figures showing the changes in expression for markers increased posttreatment such as PDCD1, GMZA, PTN, CAIX, IL18, CD28, and markers decreased posttreatment such as CCL17, ANGPT2, IL13, and CXCL13. …”

Sex hormone stimulation of CRISPR-modified HepG2 cells alters alpha-1 antitrypsin production by Emma Leacy (11872358)

“…There was also a dose-dependent decrease in AAT release, particularly in oestrogen-treated cells (Figure 1C). …”

Figure 6 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer by Jennifer M. Finan (14951382)

“…<p>HuR WT EVs are tumor promoting and directly decrease ICAM-1 expression on endothelial cells. <b>A,</b> Schematic of EV isolation from KPC WT and HuR-KO cells via SEC. …”

Table 5_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Pre-existing peat organic matter remained relatively stable; significant priming of its consumption was not observed, nor was its structural alteration.…”

Image 3_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem... by Shida Pan (12696593)

“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”

Data Sheet 1_CD8+ T cells mediate the impact of gut dysbiosis and short-chain fatty acid deficiency on accelerated arthritis progression in collagen-induced arthritis mice.docx by Xiangcong Zhao (12573181)

“…CD8⁺ T cells were significantly increased in mesenteric lymph nodes (MLN) and intestinal mucosa (IM). …”

Data of Fig 4A. by Xianyu Piao (145967)

“…Hepatic schistosomulum treated with SjCL1 antibodies <i>in vitro</i> showed significant growth retardation, although remained viable and developed intestinal heme pigmentation, indicative of hemoglobin digestion.…”

Data Sheet 1_Dynamics and drivers of the carbonate system: response to terrestrial runoff and upwelling along the Northeastern Colombian Caribbean coast.pdf by Constanza Ricaurte-Villota (14169471)

“…</p>Results<p>The results showed significant seasonal variability influenced by annual changes in coastal upwelling, rainfall, and river runoff. …”

Image 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.tif by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Microcosmic pores parameters calculation results. by Yanxu Liang (22227024)

“…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…”

ESR Fig 4, Table 1 data. by Takanori Kitagawa (20727226)

“…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …”

Data Sheet 1_Global, regional and national burden of neck pain in children and adolescents: GBD 2021 systematic analysis.pdf by Chao Sun (139686)

“…Background<p>Neck pain (NP) has emerged as a significant health concern among children and adolescents, with potential lifelong consequences. …”

Table 1_Effects of dietary amylose/amylopectin ratio on antioxidant ability and amino metabolism in the liver of weaned piglets undergoing feed transition and challenged with lipop... by Can Yang (337581)

“…Serum immunoglobulin G (IgG) concentration increased in DAR 0.80 but decreased in other groups after LPS stress (p < 0.05). …”

Data Sheet 1_Global, regional, and national epilepsy of unknown cause incidence and mortality, 1990–2036: cross-national health inequalities and predictive analytics.pdf by Lijun Wang (176511)

“…Correlation analysis revealed a significant negative association between ASDR, ASYR, and SDI, while ASIR showed a weak and statistically insignificant positive correlation with SDI. …”

Image 1_Screening of LAB strains and their co-culture fermentation with Bacillus subtilis of Cili fruit substrate: impact on γ-aminobutyric acid enrichment, key enzyme activities,... by Angelo Uriho (20992232)

“…Compared to B. subtilis fermented substrate (Bs), a significant decrease in pH (4.89, except BsLf), increase in TTA (19.30–29.20 mL) was observed after co-culture fermentation of Cili fruit. …”

CONSORT flow chart of included patients. by Zhiwei Li (131853)

“…</p><p>Conclusion</p><p>EIT parameters reveal significant differences in ventilation between VCV and PCV-VG during the laparoscopic perioperative period. …”

Table 2_The impact of telework on absenteeism, presenteeism, and return to work among workers with health conditions: a scoping review.docx by Julien Ducas (20501079)

“…In contrast, findings on presenteeism are conflicting: some studies report that telework increases the likelihood of working while sick, others suggest a decrease, and some report no significant impact or conflicting results. …”

<b>A meta-analysis of immediate and delayed discard mortality of red snapper (</b><b><i>Lutjanus campechanus</i></b><b>)</b> by Chloe Ramsay (21664871)

“…We assessed if depth, season, release method, or region predict discard mortality. We found a significant positive relationship between depth and discard mortality and that, in the western Gulf, fishing in the summer significantly increases discard mortality compared to fishing in other seasons and regions. …”

Percentage of different <i><i>d</i></i>_max/<i><i>d</i></i>_min. by Yanxu Liang (22227024)

“…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…”