Image 2_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Image3_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.jpeg by Lan Jiang (57811)

“…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …”

Image 1_CXCR7-TAGLN2 protein complex regulates invasion and metastasis in papillary thyroid carcinoma: a potential therapeutic target.tif by Chao Zeng (452370)

“…High expression of both proteins was significantly associated with lymph node metastasis in PTC patients, and a significant positive correlation was observed between CXCR7 and TAGLN2 expression levels. …”

Table_4_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... by Kexin Zhang (301752)

“…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …”

List of HipSci cell lines used in the study. by Sara Cuvertino (18892069)

“…In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. Our analysis reveals significant enrichment of differentially downregulated genes in areas containing putative enhancer regions with H3K4me1 loss. …”

Table 1_A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis.docx by Michael R. Kann (22070273)

“…Lastly, the post-operative decrease in visual analog scale pain was 5.59 [95% CI (5.23, 5.94)] in the lumbar spine and 5.49 [95% CI (4.79, 6.19)] in the thoracic spine. …”

Image 3_CXCR7-TAGLN2 protein complex regulates invasion and metastasis in papillary thyroid carcinoma: a potential therapeutic target.tif by Chao Zeng (452370)

“…High expression of both proteins was significantly associated with lymph node metastasis in PTC patients, and a significant positive correlation was observed between CXCR7 and TAGLN2 expression levels. …”

Table2_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.docx by Jiayu Ding (12005975)

“…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …”

Table 5_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Image 2_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.tif by Ben Wang (250897)

“…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…”

Data Sheet 4_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv by Ben Wang (250897)

“…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…”

Image1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”

The analyzed data of the 532 cases of this study. by Qiaolin Yu (9921122)

“…<div><p>Background</p><p>Malnutrition is a significant risk factor contributing to the progression of the elderly with pulmonary tuberculosis (TB). …”

Table5_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.xlsx by Lan Jiang (57811)

“…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …”

Data Sheet 1_Psychosocial and physiological health outcomes of outdoor green exercise versus indoor exercise in knee osteoarthritis patients coexisting with type 2 diabetes mellitu... by Yilin Jin (8070026)

“…Participants in OGC group achieved significant decrease of HbA1c than participants in ISC group.…”

List of DEGs from iPSC analysis. by Sara Cuvertino (18892069)

“…In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. Our analysis reveals significant enrichment of differentially downregulated genes in areas containing putative enhancer regions with H3K4me1 loss. …”

Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf by Gufeng Gao (16835753)

“…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). In PASMCs stimulated with PDGF-BB, a similar trend of increased p-PKC, p-IRS-1(Ser318), and p-ERK levels was observed, along with a decrease in IRS-1 expression. …”

Image4_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”

Data Sheet 1_Efficacy and safety of reduning injection for severe pneumonia: a systematic review and meta-analysis.docx by Yan Wang (15435)

“…</p>Conclusion<p>The administration of RDN injection as an adjunct therapy for SP can enhance clinical efficacy, reduce fever duration, accelerate cough resolution, shorten the time for lung rales to resolve, accelerate chest X-ray improvement, and decrease hospitalization duration. Further well-designed and standardized large sample clinical studies are needed for validation.…”

Supplementary file 2_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... by Nian Jiang (1338381)

“…Lowering the METS-IR index below 38.1 through lifestyle changes and diet control can significantly reduce the risk of cognitive impairment and may decrease the incidence of dementia.…”