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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
point increase » unit increase (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
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20901
Baseline characteristics of the study population.
Published 2025“…Widespread use of the measles vaccine has decreased measles antibody potency in the United States plasma supply. …”
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20902
Table3_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
Published 2024“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”
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20903
Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx
Published 2025“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV<sub>1</sub>), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”
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20904
Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx
Published 2025“…Background<p>Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. …”
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20905
Table 5_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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20906
DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf
Published 2025“…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…”
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20907
DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip
Published 2024“…Although the population of F4/80<sup>+</sup>CD11b<sup>+</sup> intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1<sup>+</sup>MerTK<sup>+</sup>) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”
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20908
Sex-specific brain volume changes in ECM.
Published 2025“…The total volume of midbrain (F) significantly augments in the female brain during CM. …”
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20909
Image 2_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.tif
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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20910
Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury....
Published 2025“…Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, has shown significant therapeutic benefits in clinical trials for the management of diabetes However, the specific mechanism on the treatment of diabetic liver injury with dapagliflozin is not fully understood. …”
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20911
Image 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.png
Published 2025“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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20912
Data Sheet 1_Sex differences in burnout and work-family conflict among Chinese emergency nurses: a cross-sectional study.docx
Published 2024“…Multiple linear regression analyses indicated that three dimensions of burnout including emotional exhaustion, depersonalization, and reduced work accomplishment significantly affected work–family role behavior conflict in both sexes. …”
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20913
Supplementary file 1_Effects of external diaphragm pacing combined with repetitive peripheral magnetic stimulation of the phrenic nerve on respiratory function in stroke patients.p...
Published 2025“…In all three groups, CMAP amplitude increased significantly, whereas PNCT decreased significantly (p < 0.05). …”
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20914
Table 1_Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with...
Published 2024“…</p>Results<p>The 6MWT showed significantly greater improvement in the HIIT group compared to the MCT group (P = 0.0024). …”
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20915
Data Sheet 2_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”
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20916
Data Sheet 1_Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.docx
Published 2025“…The viral load results demonstrated that the vaccine group significantly reduced viral copy numbers in serum and effectively decreased the concentration of the inflammatory cytokine IL-1β. …”
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20917
Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx
Published 2025“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”
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20918
Table 6_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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20919
Table1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf
Published 2024“…The estimated pooled procedural success rate was 100% [95% confidence interval (CI): 98%–100%, I2 = 0, P = 0.78]. Significant decreases in trans-coarctation PGs and SBP were observed. …”
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20920
Prognostic value of cardiac troponin I in acute ischemic stroke patients treated with reperfusion therapy: a multicenter retrospective cohort study
Published 2025“…Elevated cTnI was not significantly associated with sICH (OR:3.75, 95%CI 0.52–27.21, <i>p</i> = 0.19), but was independently associated with increased in-hospital mortality (OR:1.96, 95%CI 1.62–6.20, <i>p</i> = 0.025) and decreased odds of good functional outcome at 30 days (OR:0.40, 95%CI 0.19–0.84, <i>p</i> = 0.016). …”