يعرض 21,141 - 21,160 نتائج من 26,206 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly ((promoted decrease) OR (promote disease)) ))', وقت الاستعلام: 0.68s تنقيح النتائج
  1. 21141

    Table 2_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf حسب Ziqin Feng (22318243)

    منشور في 2025
    "…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …"
  2. 21142

    Supplementary file 1_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.docx حسب Zheyuan Ding (4281394)

    منشور في 2025
    "…The reported incidence of syphilis decreased by an average of −3.53% per year across all age groups (95% CI: −4.34, −2.70%). …"
  3. 21143

    Data Sheet 1_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disea... حسب Chenjing Xu (12109035)

    منشور في 2025
    "…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…"
  4. 21144

    Image 1_Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.jpg حسب Yanjiang Yang (13860452)

    منشور في 2024
    "…</p>Results<p>The IVW model indicated significant negative causal correlations between BMI and BC, ER<sup>+</sup>BC, and ER<sup>-</sup>BC. …"
  5. 21145

    Image 1_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg حسب Zheyuan Ding (4281394)

    منشور في 2025
    "…The reported incidence of syphilis decreased by an average of −3.53% per year across all age groups (95% CI: −4.34, −2.70%). …"
  6. 21146

    Data Sheet 1_Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study.pdf حسب Paulo Rodrigues-Santos (3424613)

    منشور في 2025
    "…Gene expression analysis identified changes in BTRC (decreased), IFNA1 (increased), and IL9 (increased) in PD versus SD patients (p<0.05). …"
  7. 21147

    Data Sheet 3_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf حسب Lu Ding (475637)

    منشور في 2025
    "…Metabolite analysis revealed associations between decreased proline, isoleucine, valine, and alanine levels with IS. …"
  8. 21148

    Data Sheet 1_Effect of administration routes on the efficacy of human umbilical cord mesenchymal stem cells in type 2 diabetic rats.pdf حسب Qiqiang Tao (20912420)

    منشور في 2025
    "…The contents of C-P and GLP-1 in serum increased significantly in all treatment groups, while the levels of INS, TNF-α, IL-6, IL-1β, IAA, and GSP decreased significantly. …"
  9. 21149

    Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

    منشور في 2025
    "…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"
  10. 21150

    Experimental and Numerical Investigations of Soot Formation in the Laminar to Turbulent Transition of an Acetylene Diffusion Flame حسب Shijun Chen (835302)

    منشور في 2025
    "…Soot formation from incomplete hydrocarbon combustion poses significant challenges for emission control in propulsion systems. …"
  11. 21151

    Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

    منشور في 2025
    "…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"
  12. 21152

    Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

    منشور في 2025
    "…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"
  13. 21153

    Supplementary Material for: The Effectiveness of a Hospital-Based Antimicrobial Stewardship Program: A Three-Year Observational Study حسب figshare admin karger (2628495)

    منشور في 2025
    "…Resistance rates for VRE and CRE decreased (44% to26% and 47% to42%, respectively) without statistical significance. …"
  14. 21154

    Image 4_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St... حسب Chenjing Xu (12109035)

    منشور في 2025
    "…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…"
  15. 21155

    Table 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.docx حسب Lichao Cao (276107)

    منشور في 2025
    "…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …"
  16. 21156

    Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

    منشور في 2025
    "…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"
  17. 21157

    Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx حسب Yutong Wu (3130584)

    منشور في 2025
    "…The most frequently reported AEs included fatigue, dyspnea, musculoskeletal pain, decreased appetite, cough, nausea, and constipation. …"
  18. 21158

    Table 1_Age-related lung structure changes by quantitative assessment: a cross-sectional study in a Chinese male cohort.docx حسب Meijuan Shi (16999551)

    منشور في 2025
    "…</p>Conclusion<p>Lung aging is not a linear process, and the lung structural alterations in the upper and lower lobes exhibit significant heterogeneity.</p>…"
  19. 21159

    Table 3_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf حسب Ziqin Feng (22318243)

    منشور في 2025
    "…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …"
  20. 21160

    Table 1_Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.xls حسب Yanjiang Yang (13860452)

    منشور في 2024
    "…</p>Results<p>The IVW model indicated significant negative causal correlations between BMI and BC, ER<sup>+</sup>BC, and ER<sup>-</sup>BC. …"