Image1_Clinical characteristics and early identification of augmented renal clearance in PICU patients with severe sepsis associated with MRSA infection.pdf by Haonan Wang (667218)

“…</p>Conclusion<p>ARC is a phenomenon significantly underestimated in pediatric patients with severe sepsis associated with MRSA infection, which can affect 74.9% of these patients and affects the process of anti-infection treatment and clinical outcomes. …”

Data Sheet 1_Detection of hemodynamic changes in a porcine lipopolysaccharide model of systemic inflammation using dynamic light scattering measurements of the microcirculation.pdf by Louwrina H. te Nijenhuis (20762678)

“…Both intervention groups showed a Hurst exponent decrease centrally at T2 and peripherally already at T1.…”

Data Sheet 1_Groundwater stress in Europe—assessing uncertainties in future groundwater discharge alterations due to water abstractions and climate change.docx by Linda Söller (19967598)

“…Projected GWSIs vary significantly among the scenarios. For the high-stress scenario, 58% of Europe’s land area is projected to experience a GWD decrease of at least 25% under RCP8.5 compared to 38% under RCP2.6, while the respective values are 26 and 1% for the intermediate-stress scenario. …”

Dexmedetomidine pretreatment alleviates brain injury in middle cerebral artery occlusion (MCAO) model rats by activating PI3K/AKT/NF-κB signaling pathway by Wei Gao (2085)

“…DEX pretreatment reversed the effects of MCAO as evidenced by decrease in protein expression levels of TNF-α and IL-6 associated with elevated protein expression levels of PI3K/AKT/NF-κB signaling pathway. …”

Supplementary Material for: Preliminary efficacy, tolerability, and safety analysis of Darolutamide for metastatic castration‑resistant prostate cancer: a single-center, open-label... by Yu J. (3610580)

“…The median time to PSA50 in the Darolutamide group was 1.5 months (95%CI 0.2619- 0.9545), significantly lower than that in the placebo group (3.0 months [95%CI 1.048- 3.818], p= 0.0259); The median time to PSA90 in the experimental group was 4 months (95%CI 0.3094- 1.437), 2 months shorter than that in the placebo group (6.0 months [95%CI 0.6961- 3.232]).With the median follow-up of 6 months, , the median decrease in serum PSA was -81.8% (range -60.4 to -99.9%) in the Darolutamide group and -69.4% (range -50.3 to -89.6%) in the placebo group. …”

Image 1_Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway.tif by Lu Liu (171341)

“…., a traditional Chinese botanical drug, has shown significant therapeutic effects against hepatocellular carcinoma (HCC), with its flavonoid compounds exhibiting anti-HCC activity through various mechanisms. …”

Table3_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

Table9_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

DataSheet6_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

Image 6_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …”

Presentation 4_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

DataSheet1_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.docx by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

Presentation 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

DataSheet2_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

Table13_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.docx by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

Table2_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.xls by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

DataSheet5_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

Table 3_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xlsx by Lan Wang (85307)

“…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …”

Image 3_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …”

Table 7_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls by Lan Wang (85307)

“…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …”