Image 4_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

DataSheet1_Association between amoxicillin administration and outcomes in critically ill patients with acute kidney injury.PDF by Xinyao Luo (12084194)

“…</p>Materials and Methods<p>We conducted a retrospective cohort analysis utilizing data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. …”

DataSheet1_Lipocalin-2 drives neuropsychiatric and cutaneous disease in MRL/lpr mice.docx by Sayra J. Garcia (19748644)

“…</p>Results<p>In this study, we found that LCN2 deficiency significantly attenuates neuropsychiatric and cutaneous disease in MRL/lpr lupus prone mice, likely by decreasing local infiltration of immune cells into the brain and skin and reducing astrocyte activation in the hippocampus. …”

<b>Astragalus polysaccharide and </b><b><i>Clostridium butyricum</i></b><b> synergistically inhibit bone loss in mice with humanized intestinal flora</b> by Hongtao Zhang (20774453)

“…We used a humanized intestinal flora mouse model and showed that APS-CB significantly inhibited bone loss caused by simulated weightlessness. …”

Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…Administration of exogenous H₂S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”

Data Sheet 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.pdf by Yasufumi Kobayashi (5481530)

“…By contrast, K⁺ accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”

Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…Administration of exogenous H₂S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”

Data Sheet 1_Land use change has profoundly altered the process of bacterial community assembly in the northeastern black soil zone.pdf by Ning Sun (162468)

“…Co-occurrence network analysis showed that reclamation reduced interspecies interactions and significantly decreased network complexity, connectivity, and cohesion (P < 0.05). …”

Data Sheet 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.xlsx by Bing Gu (276393)

“…Administration of exogenous H₂S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”

Data Sheet 1_Efficacy and safety of shensong yangxin capsules for persistent atrial fibrillation: a Systematic Review and meta-analysis of randomized controlled trials.docx by Yifan Chen (446592)

“…We assessed methodological quality with the Cochrane Risk of Bias Tool 2.0, and conducted meta-analyses with RevMan 5.4.…”

Data Sheet 1_Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11.docx by Ling Li (38566)

“…RNA-seq analysis was performed to study transcriptional changes in these cells.</p>Results<p>We found that bryostatin-1 improved the expansion and decreased PD-1 expression of HIV-specific CD8+ T cells. …”

Data Sheet 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.zip by Na Wang (193263)

“…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

DataSheet1_The Impact of Unmet Healthcare Needs on the Perceived Health Status of Older Europeans During COVID-19.pdf by Šime Smolić (15918211)

“…</p>Results<p>Findings indicate that unmet healthcare needs decreased throughout the pandemic but significantly contributed to the worsening of SRH among older adults. …”

Table 1_Epicatechin gallate and its analogues interact with sortase A and β-lactamase to suppress Staphylococcus aureus virulence.docx by Fei Teng (201085)

“…The ability of β-lactam antibiotics to combat S. aureus infections is limited by the presence of β-lactamases in this pathogen. In this study, we determined that epicatechin gallate (ECG) and its analogues inhibited the transpeptidase activity of sortase A by interacting with it directly, and the biofilm formation and adhesion abilities of the bacterium decreased after treatment with ECG and its analogues. …”

Synthesis and biological evaluation of quinoxaline derivatives as ASK1 inhibitors by Xiaorui Han (1401655)

“…The Oil Red O staining experiment showed that <b>26e</b> decreased the lipid droplets in a dose-dependent manner. …”

Water Hyacinth as a Renewable Source of Cellulose Nanofibers: Fabrication and Properties of Optically Transparent Nanocomposites by Supachok Tanpichai (2084065)

“…Moreover, the CNF nanopaper significantly decreased the coefficient of thermal expansion of the acrylic resin from 192.3 to 16.3 ppm K⁻¹, which is comparable to that of borosilicate glass. …”

Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... by Xuan Chen (158617)

“…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …”

Neurochemical identity of dFB^23E10Ո^84C10 neurons. by Joseph D. Jones (13883524)

“…A Kruskal–Wallis ANOVA followed by Dunn’s multiple comparisons revealed that acutely silencing VGlut-AD; 84C10-DBD and 84C10-AD; ChAT-DBD neurons significantly decreases sleep. ****<i>P</i> < 0.0001. …”

Supplementary file 1_Temporal interaction information and laser evoked responses: preliminary results in fibromyalgia patients with small fibers pathology.docx by Livio Clemente (22152382)

“…</p>Methods<p>Seventy-nine FM patients, categorized into three groups based on skin biopsy findings (normal innervation n 19, proximal denervation n 53, and both proximal and distal denervation n 7), and 14 control subjects were studied. We used cluster-based permutation tests (p < 0.05) to identify significant clusters of TII between cortical components recorded using a 64-channel electroencephalography (EEG) system - with focus on the Cz electrode - and subjective pain ratings to quantify synergy or redundancy between the LEP signal time points and Visual Analog Scale (VAS).…”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”