Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…This effect was observed under both basal and IFNα stimulated conditions. Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. …”

Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…This effect was observed under both basal and IFNα stimulated conditions. Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. …”

Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif by Matthew C. Austin (20633168)

“…This effect was observed under both basal and IFNα stimulated conditions. Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. …”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…This effect was observed under both basal and IFNα stimulated conditions. Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. …”

Data_Sheet_1_Analysis of spatial and temporal characteristics and evolution of green total factor productivity in agriculture in the lower Yellow River basin.xlsx by Junru He (20158257)

“…<p>The construction of ecological barriers in the Yellow River Basin represents a significant step toward reducing agricultural carbon emissions, achieving carbon neutrality, and reaching carbon peaking in China. …”

Data Sheet 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx by Manling Zhang (566460)

“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”

Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx by Manling Zhang (566460)

“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”

Study group background characteristics. by Zicheng Hu (3825313)

“…Highest CSF HIV-1 RNA concentrations were present in the <b><i>HAD</i></b> group, while the <b><i>CD4-defined</i></b> groups showed the ‘inverted U’, or <i>lymphoid</i>, pattern of change with lower concentrations at the extremes (in the <b><i>CD4+ >500</i></b> and <b><i>CD4+ <50</i></b> groups) than in the middle ranges (<b><i>CD4+ 350</i></b>–<b><i>499</i></b>, <b><i>200–345</i></b> and <b><i>50–199</i></b> groups). We previously reported the association of this pattern with that of the CSF WBC counts as also noted in this study (see <b>Fig 1K</b> below), suggesting that these two findings were causally related [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012470#ppat.1012470.ref045" target="_blank">45</a>]. …”

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

Direction variability for each replicate and sub-replicate. by Damien Genettais (21387230)

“…<p>When slugs migrated towards light (<b>A</b>) direction variability decreased significantly with the increased number of cells (p-value<10⁻³) within slugs for all replicates. …”

Proteomic analysis of _sEVs. by María-Angélica Calderón-Peláez (2851865)

“…C) Regarding the biological processes, the significantly increased proteins were involved in immune response, while decreased proteins were mainly involved in cell adhesion and developmental processes. …”

Data Sheet 1_Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.pdf by Lucie Pejšková (20467025)

“…Investigation of the potential role of SDC4 in the pathogenesis of WB myopathy revealed a decreased tendency in SDC4 gene expression and increased shedding of its ectodomain. …”

Data Sheet 1_Flaxseed intervention and reproductive endocrine profiles in patients with polycystic ovary syndrome: an open-labeled randomized controlled clinical trial.pdf by Zahra Najdgholami (21009269)

“…The LH/FSH ratio also significantly decreased in the flaxseed group (mean treatment effect: -0.341, 95% CI: -0.63 to -0.08, p = 0.031). …”

Supplementary Material for: Pharmacokinetic Properties of Dapagliflozin in Patients with Stage 4 Chronic Kidney Disease by figshare admin karger (2628495)

“…The pharmacokinetic data on dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, is limited in patients with severe renal impairment. …”

Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... by Xuan Chen (158617)

“…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …”

<b>Differences in White Matter Microstructure in Children With Type 1 Diabetes Persist During Longitudinal Follow up: Relation to Dysglycemia</b> by Nelly Mauras (8103110)

“…Associations with glycemic and cognitive measures were assessed.</p><p dir="ltr">We observed in 182 children (121 type 1 diabetes, vs. 61 controls) who had testing at Time 4 that FA increased, and RD, AD, MD decreased significantly in both groups, with no differences between groups for FA, RD and MD over time. …”

Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx by Lei Jin (120473)

“…High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …”

Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Table 1_Effect of membrane rigidification on the BrAFP1 expression and cold-tolerance in Brassica rapa.docx by Xiaoyun Dong (9706099)

“…The expression levels of cold-responsive genes, including cyclic nucleotide-gated channel 1 (CNGC1), open stomata 1 (OST1), and inducer of CBF expression 1 (ICE1), as well as membrane fluidity-related genes, such as acyl-lipid desaturase 2 (ADS2), fatty acid desaturase 2 (FAD2), and sensitive to freezing 2 (SFR2), were significantly increased following DMSO pretreatment, while BA treatment significantly inhibited the expression of these genes. …”