Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor... حسب Ying Feng (151159)

"…In contrast, metabolic disease burden was significantly elevated in postmenopausal women, exhibiting a pattern distinct from that of PCOS.…"

Image 2_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... حسب Chunxiu Zhao (21650204)

Image 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... حسب Chunxiu Zhao (21650204)

Image 3_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... حسب Chunxiu Zhao (21650204)

Data Sheet 2_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... حسب Junhong Yang (7807046)

"…</p>Materials and methods<p>We conducted a cross-sectional study on donor hemovigilance data reported to the national network from 2020 to 2022 in China. …"

Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... حسب Junhong Yang (7807046)

"…</p>Materials and methods<p>We conducted a cross-sectional study on donor hemovigilance data reported to the national network from 2020 to 2022 in China. …"

Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur... حسب Yangtian Jiao (21725018)

"…Decomposition analysis highlighted the role of epidemiological improvements, balanced by the impacts of population growth and aging. Projections indicate a continued global decline, with a 43.81% reduction in the ASIR and a 62.92% decline in the age-standardized DALY rate by 2036.…"

Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... حسب Frederick Berro Rivera (12679463)

"…</p> <p>GLP-1RA treatment modestly decreased LDL-C and TC but did not significantly affect triglycerides, VLDL-C, or HDL-C.…"

Data Sheet 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels ba... حسب Chunxiu Zhao (21650204)

Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of... حسب Long Chen (315739)

"…Background<p>Interstitial lung disease (ILD) constitutes a significant global health challenge. However, existing epidemiological studies predominantly focus on worldwide and regional distribution patterns, while a substantial knowledge gap persists regarding the epidemiological characteristics of ILD among middle-aged and older adults (50–74 years). …"

Data Sheet 1_Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in hum... حسب William D. Tolbert (7870697)

"…Its affinity for IgG and ability to mediate ADCP is influenced by allelic polymorphisms. In humans, a single amino acid polymorphism at position 131, where histidine (H) is substituted with arginine (R), leads to decreased IgG1 and IgG2 subclass binding affinity and, consequently, lower efficiency of phagocytic responses. …"

Table 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... حسب Jiaoli Xu (20871584)

"…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …"

Image 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... حسب Jiaoli Xu (20871584)

"…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …"

Table 2_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... حسب Jiaoli Xu (20871584)

"…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …"

Table 4_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... حسب Jiaoli Xu (20871584)

"…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …"

Table 3_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... حسب Jiaoli Xu (20871584)

"…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …"

Image 2_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... حسب Jiaoli Xu (20871584)

"…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …"

<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... حسب Silvia Torchio (611349)

"…Here, we investigated how the c.316-1G>A and c.757A>T <i>WFS1</i> mutations, which yield partially functional Wolframin, affect the molecular functions of β cells and explored the therapeutic potential of the Glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide. …"

Table 1_Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and... حسب Yaqi Yin (7280069)

"…This study evaluated the effects of folic acid supplementation combined with B vitamins (B12 and B6) on homocysteine levels and complication risk in adults with type 2 diabetes mellitus.</p>Methods<p>We conducted a systematic search of eight databases from inception through August 30, 2025. …"

<b>Association between myristic acid in plasma triglycerides and metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: A comprehensive analysis... حسب Shigero Hosoe (21735020)

"…</p><p dir="ltr">Initially, we conducted a plasma lipidome analysis using supercritical fluid chromatography-tandem mass spectrometry in 143 patients with type 2 diabetes with and without MASLD. …"