Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Effect of sample size on reproducibility. by Jan Willem Koten (17743224)

S1 Data - by Jan Willem Koten (17743224)

“…Moreover, it is unclear how within-subject time course reliability limits the robust detection of connectivity on the group level. We estimated connectivity from a working memory task. …”

Connectivity statistics. by Jan Willem Koten (17743224)

“…Moreover, it is unclear how within-subject time course reliability limits the robust detection of connectivity on the group level. We estimated connectivity from a working memory task. …”

Reproducibility of response time and brain measures. by Jan Willem Koten (17743224)

Effect of corrections on connectivity maps. by Jan Willem Koten (17743224)

Original data2. by Lan Zeng (638254)

“…<div><p>Diabetic retinopathy (DR) is a leading cause of blindness. We hypothesised that the long non-coding RNA <i>RP11-502I4.3</i> may be involved in angiogenesis associated with DR. …”

Original data1. by Lan Zeng (638254)

“…<div><p>Diabetic retinopathy (DR) is a leading cause of blindness. We hypothesised that the long non-coding RNA <i>RP11-502I4.3</i> may be involved in angiogenesis associated with DR. …”

Participant demographics. by Anita B. Frohlich (20660615)

“…In contrast to the EEG results, heart rate, heart rate variability, and cognitive performance assessed with a working memory task did not differ significantly by breathing condition. …”

Theta power for frontal midline ROI. by Anita B. Frohlich (20660615)

“…In contrast to the EEG results, heart rate, heart rate variability, and cognitive performance assessed with a working memory task did not differ significantly by breathing condition. …”

Chitosan-Based Thermal-Coagulation Hydrogel System Driven by Multiple Interactions: Oxidation-Induced Fast Gelation and Enhanced Performance by Yifan Liu (219681)

“…By controlling the grafting rate, it was found that the solution pH and p<i>K</i>_a of CS-C were both affected by the decrease of the amino groups, whereas the gelation time and the required β-GP content for gelling significantly decreased. …”

Chitosan-Based Thermal-Coagulation Hydrogel System Driven by Multiple Interactions: Oxidation-Induced Fast Gelation and Enhanced Performance by Yifan Liu (219681)

“…By controlling the grafting rate, it was found that the solution pH and p<i>K</i>_a of CS-C were both affected by the decrease of the amino groups, whereas the gelation time and the required β-GP content for gelling significantly decreased. …”

Chitosan-Based Thermal-Coagulation Hydrogel System Driven by Multiple Interactions: Oxidation-Induced Fast Gelation and Enhanced Performance by Yifan Liu (219681)

“…By controlling the grafting rate, it was found that the solution pH and p<i>K</i>_a of CS-C were both affected by the decrease of the amino groups, whereas the gelation time and the required β-GP content for gelling significantly decreased. …”

The raw data for Fig 4. by Hongjoo An (21703199)

“…Luciferase assay and human and mouse brain multi-omics data show that, during the differentiation of OL precursor cells (OPCs) into OLs, the enhancer activity of Sox10-E1 does not change while that of Sox10-E2 decreases significantly. Chromatin interaction data indicate that the two <i>Sox10</i> enhancers lie close to the border of the <i>Sox10</i> topologically associating domain (TAD). …”

The raw data for S2 Fig. by Hongjoo An (21703199)

“…Luciferase assay and human and mouse brain multi-omics data show that, during the differentiation of OL precursor cells (OPCs) into OLs, the enhancer activity of Sox10-E1 does not change while that of Sox10-E2 decreases significantly. Chromatin interaction data indicate that the two <i>Sox10</i> enhancers lie close to the border of the <i>Sox10</i> topologically associating domain (TAD). …”

The raw data for Fig 6. by Hongjoo An (21703199)

“…Luciferase assay and human and mouse brain multi-omics data show that, during the differentiation of OL precursor cells (OPCs) into OLs, the enhancer activity of Sox10-E1 does not change while that of Sox10-E2 decreases significantly. Chromatin interaction data indicate that the two <i>Sox10</i> enhancers lie close to the border of the <i>Sox10</i> topologically associating domain (TAD). …”

The raw data for S4 Fig. by Hongjoo An (21703199)

“…Luciferase assay and human and mouse brain multi-omics data show that, during the differentiation of OL precursor cells (OPCs) into OLs, the enhancer activity of Sox10-E1 does not change while that of Sox10-E2 decreases significantly. Chromatin interaction data indicate that the two <i>Sox10</i> enhancers lie close to the border of the <i>Sox10</i> topologically associating domain (TAD). …”