Image 5_Effects of gender affirming hormone therapy with testosterone on renal function of assigned female at birth transgender people: a meta-analysis.tif by Daniele Tienforti (11665717)

“…When the CKD-EPI equation was referred to the perceived (male) gender, eGFR significantly decreased after 12 months but not after 6 months of T-GAHT. …”

Table 1_Epidemiological study of thyroid cancer at global, regional, and national levels from 1990 to 2021: an analysis derived from the Global Burden of Disease Study 2021.docx by Lu Zhang (50563)

“…</p>Conclusion<p>Over the past three decades, the age-standardized prevalence rate of thyroid cancer has increased, while the age-standardized mortality rate and DALY rate have decreased. Significant variations in prevalence, morbidity, and mortality exist across regions and countries. …”

Supplemental information to: Female mice with HSD17B1 inactivation show mild hyperandrogenism without notable impact on reproductive function or bone by Arttu Junnila (22503041)

“…However, the effect of HSD17B1 inactivation on female reproductive development and function was mild, primarily resulting in a slight decrease in ovarian weight in older HSD17B1-KI mice, without notable effects on fertility. …”

Supplementary file 1_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…Aims and background<p>Autophagy plays an increasingly significant role in diabetic nephropathy (DN), but the mechanism by which autophagy participates in DN injury is not well understood. …”

Data Sheet 1_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf by Tianmin Huang (20561477)

“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”

Data Sheet 1_Discovery of N′-(1-(coumarin-3-yl)ethylidene)benzenesulfonohydrazide as a novel wound healing enhancer: synthesis, biological assessment, and molecular modeling.pdf by Eman F. Khaleel (4844745)

“…The results indicated that CBSH significantly promotes the migration of skin fibroblast cells and enhances the wound healing process. …”

Table 6_Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021.doc by Shujun Tan (20011518)

“…</p>Results<p>The global burden of NE has significantly declined over the past three decades. Between 1990 and 2021, the global ASIR decreased from 20.22 to 17.16, while the number of cases fell from 1,295,891.1 to 1,061,448.15, reflecting an 18.09% reduction. …”

Video 2_Case Report: Allogeneic adipose-derived mesenchymal stem cells for severe feline chronic kidney disease.mp4 by Yizhe Song (11859734)

“…Concurrently, laboratory results revealed a decrease in key renal biomarkers (SCr, BUN, and P) and an amelioration of the non-regenerative anemia. …”

Table1_Comprehensive transcriptome analysis of AP2/ERFs in Osmanthus fragrans reveals the role of OfERF017-mediated organic acid metabolism pathway in flower senescence.xlsx by Jing-Jing Zou (19743220)

“…Overexpression of OfERF017 leads to significant enrichment of genes in organic acid metabolism pathways, which leads to a decrease in organic acid levels and promoting the flower senescence of O. fragrans. …”

Data Sheet 1_Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference.docx by Changsheng Yuan (2369854)

“…Root length and middle and lower section diameters showed significant increases from 1 to 2 years, stabilizing from 2 to 3 years. …”

Table 1_Linking the Planetary Health Diet Index to sarcopenia: the mediating effect of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (N... by Huan Chen (6545)

“…Analysis of the dose–response curve suggested a linear relationship between PHDI and sarcopenia. Furthermore, a significant positive association was identified between NHHR and sarcopenia [OR = 1.09, 95% CI: 1.03, 1.16], with NHHR found to decrease as PHDI increased [beta coefficient (β) = −0.09, 95% CI: −0.11, −0.06]. …”

Sample size in each occupational subgroup. by Maryam Rafiee (10368504)

“…Furthermore, an increase of one point in work ability score leads to a decrease in WMSDs in the neck, wrists/hands, low back and hips/thighs regions by 13.5%, 8%, 11.5%, and 9%, respectively.…”

Prediction of transition readiness. by Sharon Barak (4803966)

“…In most transition domains, help needed did not decrease with age and was not affected by function. …”

Data Sheet 1_Antarctic krill habitat suitability variation in the Southern Ocean over 20 years.pdf by Yiyang Tan (18227048)

“…<p>Antarctic krill (Euphausia superba) is a key species that sustains the biodiversity of the Southern Ocean and is a protected and restricted fishing target in this region. Considering the significant impacts of climate change on the ecological environment of the Southern Ocean, it is critical to understand the long-term spatio-temporal habitat distribution of Antarctic krill. …”

Crystal violet assay. by Takanori Kitagawa (20727226)

“…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …”

Table 4_Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021.docx by Yue Li (102191)

“…Compared with 1990, although the ASIR and age-standardized disability-adjusted life years rate (ASDALYsR) decreased, absolute numbers increased significantly. …”

Table1_Impacts of elevated CO2 and partial defoliation on mineral element composition in rice.docx by Bo Gao (106513)

“…Significant changes in the concentrations of N, S, Fe, and Zn in straw were noted under elevated CO₂, with average decreases by 7.1, 7.2, 11.6, and 10.1%, respectively. …”

Table 1_An analysis of the intestinal microbiome combined with metabolomics to explore the mechanism of how Pangxiejiao tea improves metabolic disorders in HFFD-treated rats.docx by Wanchun Wang (425177)

“…Furthermore, PXJ was found to decrease the Firmicutes/Bacteroidota ratio, modulated gut microbiota composition, and maintain microbial homeostasis. …”

Table 1_The association between Dietary Index for Gut Microbiota and sarcopenia: the mediating role of Dietary Inflammatory Index.docx by Hongyang Gong (19561855)

“…RCS analysis revealed a significant linear relationship between DI-GM and sarcopenia. …”

Supplementary file 2_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…Aims and background<p>Autophagy plays an increasingly significant role in diabetic nephropathy (DN), but the mechanism by which autophagy participates in DN injury is not well understood. …”