<b>RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy</b> by Hongmei Qian (538647)

“…</p><p><br></p><p dir="ltr"><b>Results:</b> In glaucomatous mice, RTA408 significantly reduces the apoptosis levels of RGCs and decreases RGC loss. …”

Image 1_High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota.tif by Yu Xia (8822)

“…Furthermore, oral administration of high-dose thiamine also regulated HFFD-induced gut microbiota dysbiosis by reshaping its structure and composition of gut microbiota, such as increasing the relative abundance of Actinobacteria and Bifidobacterium pseudolongum, and reducing the relative abundance of Proteobacteria and Ruminococcus gnavus, accompanied by decreased level of gut-derived endotoxin. Finally, significant correlations were found between obesity-related phenotypes and gut microbiota through correlation analysis.…”

Table 1_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx by Wenjing Chang (8334480)

“…However, non-adherence remains a significant challenge, affecting treatment efficacy and patient prognosis. …”

Drawing test data. by Run-Zhi Jia (21262716)

“…As the confining pressure increased, the ratio of tensile cracks in rock sample failure decreased, while the ratio of shear cracks increased. …”

Economic resilience results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Test results related to model selection. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Image 2_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

Data Sheet 1_Assessing ecological environmental quality and conservation effectiveness in the World’s largest urban green heart using the remote sensing ecological index (RSEI) and... by Chongbo Wu (22135075)

“…The findings reveal that: (1) The RSEI demonstrated an average annual growth rate of 0.0038 years^-1 over 31 years, with significant increases during 1990–2013 (0.0045 years^-1) and 2013–2020 (0.0089 years^-1). (2) Comparing pre- and post-GH policy implementation periods (1990–2013 vs. 2013–2020), areas showing EEQ improvement increased from 77.15% to 89.69%, while areas with stable and decreased EEQ declined from 22.36% to 10.17%. (3) GH policy demonstrates substantial positive conservation effects, with both GH and the 3 km buffer zone exhibiting EEQ improvements. …”

Transgenic barley over-expressing <i>Aspergillus niger</i> phytase phyA in field trials by T Vlčko (22248667)

“…Increased phytase activity gradually decreased over the generations showing the most significant drop in the initial years of field trials. …”

Data Sheet 1_Effects of simulated litter inputs on ecological niches and interspecific connectivity of alpine meadow plants.xlsx by Weishan Lin (20756891)

“…Introduction<p>Plant litter enters the soil as the main nutrient for alpine meadow ecosystems, and the amount of litter input has a significant effect on alpine meadow plant diversity, ecological niches, and interspecific connectivity.…”

Table3_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx by Mingming Hou (11341656)

“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”

<b><i>Assessment of Diseases’ Prevalence, Nutrition and Associated Factors in a Conflict-Affected Region: A Study in Leepa Valley, Azad Jammu and Kashmir, Pakistan</i></b> by Zoha Khan (19100603)

“…Moreover, 76.3% reported decreased employment opportunities in Leepa Valley due to the ongoing border conflicts. …”

Table 1_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx by Guilin Ren (18720749)

“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”

Image 2_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif by Xiaochuan Yu (2410861)

“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”

Table 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”

Evaluation indicators system of ER. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Comparison of the effectiveness of Models 1, 2a and 2b in estimating fetal fraction (FF) based on telomere content. by Zuzana Holesova (15253816)

“…The RMSE decreased to 0.0216 for the <i>seqFF</i> model and 0.0190 for the <i>comboFF</i> model, indicating a strong predictive improvement. …”

The statistics of residential land price. by Wenqi Li (137889)

“…<div><p>Exploring the spatial structure of residential land prices within metropolitan areas is crucial for identifying regional development disparities. It holds significant practical value for guiding the rational allocation of resources, optimizing land use efficiency, and promoting collaborative development across the metropolitan region. …”

Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip by Zixu Wang (6297470)

“…The study investigated the oxidative damage in TM3 cells induced by H₂O₂ and demonstrated that salidroside significantly decreased the levels of ROS and MDA, while increasing the levels of testosterone, SOD, GSH. …”

Evaluation indicators system of DI. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”