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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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17681
Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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17682
Data Sheet 10_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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17683
Data Sheet 9_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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17684
Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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17685
Data Sheet 4_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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17686
Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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17687
Table 1_Uniaxial tensile material properties of adult Chinese dura mater: investigating the influence of age, sex, and anatomical site.docx
Published 2025“…</p>Results<p>indicated significant age-related degradation: E<sub>C</sub>, σ<sub>Tf</sub>, ε<sub>Tf</sub>; and MaxForce significantly decreased with age (median E<sub>C</sub> declined from 28.0 MPa in young adults to 15.3 MPa in the elderly, P < 0.05; median ε<sub>Tf</sub> from 0.215 to 0.156, P < 0.05), while E<sub>E</sub> showed no significant age correlation (P = 0.10). …”
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17688
Over-expression of Fas2 in the wing imaginal disc causes an EGFR-dependent reduction in organ size.
Published 2024“…This phenotype is significantly enhanced by the heterozygosity for the <i>Egfr</i> mutant <i>top</i> in <i>MS1096-GAL4/+; UAS-fas2</i><sup><i>TRM</i></sup><i>/Egfr</i><sup><i>top</i></sup> individuals (T <i>Egfr/+</i>). …”
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17689
Robust chain-length specific reductions in some intermediate chain and long chain PE phospholipids in peroxisomal mutant brain.
Published 2025“…</b> Levels in mol% of PE 33:3 in <i>pex2</i> and <i>pex16</i> mutant brains show significant decreases in <i>pex</i> mutant brains. For PE 33:3 in <i>pex2</i><sup>2</sup> brain and <i>pex2</i><sup><i>1</i></sup> brain, levels are dramatically reduced compared to controls (ratio 0.225, 0.200 respectively, p < 0.001, p < 0.001 respectively) and <i>pex2</i><sup><i>2</i></sup> brain compared to rescue (ratio 0.244, p < 0.001), and <i>pex2</i><sup><i>1</i></sup> compared to rescue (ratio 0.220, p < 0.001). …”
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17690
Algorithms for designing continuous curricula A: Decision tree showing the continuous version of ADP which includes actions that “grow” and “shrink” the increments between continuo...
Published 2025“…<p>See the text for more details of the task in the continuous setting. B: ADP significantly outperforms INC when the task is difficult (low <i>ε</i>). …”
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17691
Data Sheet 1_Unveiling frailty: comprehensive and sex-specific characterization in prematurely aging PolgA mice.pdf
Published 2024“…While these approaches have been applied to aging mice, their effectiveness in prematurely aging mouse models such as PolgA<sup>D257A/D257A</sup> (PolgA) has not been completely explored. We demonstrated that frailty became evident in PolgA mice around 40 weeks, validated through body weight loss, reduced walking speed, decreased physical activity, and weaker grip strength. …”
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17692
Water bridges
Published 2024“…The frequency of water bridges within each topology decreases with the increasing degree of the water node, with simple bivalent water bridges outnumbering the higher order topologies. …”
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17693
Table 1_Immediate effects of extracorporeal radial pressure wave therapy on dystonia, static plantar pressure distribution, and balance in patients with Parkinson’s disease.docx
Published 2025“…</p>Results<p>After ERPWT, significant decreases were observed in muscle tone, stiffness, and elasticity of the achilles tendon on the more PD-affected side and the anterior aspect of the planta on both feet (p < 0.05). …”
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17694
Table 1_A study of the adjunctive therapeutic effects of a 3-week bamboo forest therapy on chronic diseases in the elderly.docx
Published 2025“…Diabetic participants showed significant decreases in fasting and pre-bedtime blood glucose levels (p < 0.001), along with reduced blood glucose fluctuations post-meal. …”
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17695
Image 1_The efficacy of sequentially comprehensive treatment based on surgery in the treatment of keloids: a retrospective study.jpeg
Published 2025“…The clinical response rate of tumor-type keloids (95.8%) was higher than that of inflammatory-type (70.0%) with a significant difference (P = 0.040). After treatment, the color, blood vessel distribution, softness, thickness, and VSS score were all decreased, and the difference was statistically significant (P < 0.001).…”
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17696
Table 2_The cerebral metabolic mechanism of group computer magnanimous therapy based on magnetic resonance spectroscopy: effects on improving magnanimous-enterprising levels of lun...
Published 2024“…Significant increases in NAA/Cr levels were observed in the right amygdala, and significant decreases in mI/Cr levels were observed in the right cingulate gyrus in the GCMTG. …”
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17697
Table 1_The cerebral metabolic mechanism of group computer magnanimous therapy based on magnetic resonance spectroscopy: effects on improving magnanimous-enterprising levels of lun...
Published 2024“…Significant increases in NAA/Cr levels were observed in the right amygdala, and significant decreases in mI/Cr levels were observed in the right cingulate gyrus in the GCMTG. …”
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17698
Table 2_Following changes in brain structure and function with multimodal MRI in a year-long prospective study on the development of Type 2 diabetes.xlsx
Published 2025“…There were no significant changes in cognitive or motor behavior over the yearlong study but there was a significant increase in sensitivity to peripheral pain in diet fed rats. …”
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17699
Table 1_Following changes in brain structure and function with multimodal MRI in a year-long prospective study on the development of Type 2 diabetes.xlsx
Published 2025“…There were no significant changes in cognitive or motor behavior over the yearlong study but there was a significant increase in sensitivity to peripheral pain in diet fed rats. …”
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17700
Figure 2 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer
Published 2025“…Unpaired two-tailed <i>t</i> tests were used to determine statistical significance relative to IgG. *, <i>P</i> < 0.05; **, <i>P</i> < 0.01; ns, not significant. …”