Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

“…A subseries of these molecules displays cellular inhibition of Ras–Raf binding, as well as decreased phosphorylation of the downstream protein ERK, demonstrating that potent multivariant Ras inhibitors can be accessed from this novel pocket.…”

Tetraspanins variably affect the virulence of <i>E</i>. <i>histolytica</i>. by Han Jiang (195350)

Melting curves. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Original blot and gel image data. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Transfection sequences. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Experimental data. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

a, Anti-correlation of gene expression between <i>dmdR1</i> and its predicted regulon. Left: Pearson correlation coefficients (PCCs) between <i>dmdR1</i> and all genes with a DmdR1 position weight matrix (PWM) score greater than 15 in their regulatory region. The vertical dashed line marks the refined PWM score threshold of 22.875. The horizontal dotted lines mark PCC = ±0.43, corresponding to an adjusted <i>p</i>-value of 0.05. Right: Target genes immediately downstream of a predicted DmdR1 binding site, ordered by decreasing PWM score.... by Hannah E. Augustijn (10773096)

“…Right: Target genes immediately downstream of a predicted DmdR1 binding site, ordered by decreasing PWM score. …”

HSV-1 infection modulates the fatty acid synthase. by Camilla Albano (16446679)

Downregulation of CD36 impaired phagocytic capacity and is associated with a proinflammatory phenotype of <i>Mst1</i> deficiency macrophages. by Jianyang Li (461703)

Comparing A) ROS and B) GSH levels in COCs versus DOs recovered from PMSG-stimulated NMRI mice cultured in absence or presence of 0.5 µM PA during IVM. Data are presented as means... by Shahrzad Ronasi (20933556)

CTV p20 interacts with autophagy-related proteins NbATG8a and NbATG8f and induces autophagy. by Yongle Zhang (11355546)

CiLV-C p29 acts as an RNA-binding protein and interacts with eukaryotic initiation factor 4A (eIF4A). by Mikhail Oliveira Leastro (5736329)

Effect of NPRC KO on fibrotic markers. by Liming Wang (114648)

“…<p>(6A) The myofibroblast marker alpha-SMA was significantly increased in glomerular preparations from WT Gq mice compared to controls. …”

Effects of increasing gravel on initial escape latency in non-injured <i>vs.</i> by Ella R. Dockendorf (21533334)

“…</b> However latency was significantly decrease for the 40 g condition in the injured day 0 animals. **** indicates significant differences across increasing amounts of gravel (p < 0.0001). * indicates a post-hoc test confirming a significant difference between injured and non-injured animals 40 g (p < 0.05).…”

Effects of injury on operant conditioning and memory. by Ella R. Dockendorf (21533334)

Figure interpretation guide and global results. by Jean-Francois Gehanno (13229260)

“…</p><p>Overall, 23,951 and 26,538 questionnaires were collected for the 2010–2011 and 2018–2019 periods, respectively. Job demand significantly decreased and job resources significantly increased between 2010–2011 and 2018–2019 while physical workload decreased. …”

Dimensions description and scales used. by Jean-Francois Gehanno (13229260)

“…</p><p>Overall, 23,951 and 26,538 questionnaires were collected for the 2010–2011 and 2018–2019 periods, respectively. Job demand significantly decreased and job resources significantly increased between 2010–2011 and 2018–2019 while physical workload decreased. …”

Flowchart of Methodology. by Kamal Hossain (331680)

“…</p><p>Results</p><p>Dengue cases in Bangladesh exhibited a significant increase from 2019 to 2023 (excluding 2020 data), with a cumulative total of 513,344 reported cases. …”

(A) Activity of SOD under B stress; (B) Activity of POD under B stress; (C) Activity of CAT under B stress; (D) Activity of APX under B stress; (E) Content of MDA under B stress ac... by Qiang Li (8118)

The spatial pattern of dengue including hotspot and coldspot in Bangladesh in 2019–2023. by Kamal Hossain (331680)