Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”

Methodology flow chart. by Sidra Aman Rana (14167473)

“…Moreover, the area of open land decreased significantly from 68.46% to 18.92%whereas the area under the built environment increased significantly from 7.77% to 36.51% from 1999—2019. …”

Table 1_Supplementation of Yupingfeng polysaccharides in low fishmeal diets enhances intestinal health through influencing the intestinal barrier, immunity, and microflora in Macro... by Mingyang Liu (426690)

“…</p>Results<p>The LF diet significantly reduced growth performance parameters compared to the control group. …”

Conditional Knockout of Serine Racemase in Microglia Alleviates Alzheimer -like Pathology and Behavior by Reducing Neuroinflammation through Enhancing Histone Lactylation by shengzhou Wu (22341388)

“…Further, addition of C646, a p300 inhibitor or oxamate, an inhibitor of lactate dehydrogenase A, significantly reversed arginase1 or interleukin-10 mRNA levels in srr-/- microglia. …”

Fig 9 - by David G. Morgan (1459003)

“…The trendlines for unadjusted data are logarithmic and steeply decreasing, while those for the adjusted data are approximately linear and flat (with gradients not significantly different to zero), showing that adjustment by <i>J</i> can compensate for the effect of relative movement.…”

Loading Thiacorrole with Various Aromatic Rings: Enhanced NIR Absorption and Improved OER Activity by Jiayang Liu (10650926)

“…DFT calculation indicates the peripheral annulations reduce the HOMO–LUMO gaps through the significantly decreasing LUMO levels with respect to HOMO levels. …”

Table 1_Investigating the Gut Microbiota Profile in Prehypertensive Individuals Exhibiting Phlegm-Dampness Constitution.docx by Ning Yu (358970)

“…Compared with those in the NPDC or BC group, the relative abundances of o_RF39, f_Porphyromonadaceae, f_Christensenellaceae, g_parabacteroides, and g_nitrobacteria in the PDC group were significantly greater. The random forest analysis results revealed that Alistipes, Butyricimonas, Odoribacter, Parabacteroides, and Corynebacterium are bacterial genera that significantly differ between the PDC and NPDC groups and greatly contribute to group differentiation. …”

Image 3_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg by Shuting Hua (21264785)

“…The decline in disease burden was most pronounced in high-SDI regions, while low-SDI regions faced a significantly higher disease burden and exhibited notable regional disparities. …”

Supplementary file 1_Effects of microbial organic fertilizers on soil microbial communities and physicochemical properties in tobacco cultivation.docx by Shengli Wang (4318522)

“…Furthermore, an assessment of tobacco leaf morphology, yield, and quality demonstrated that the application of MOF resulted in a 21.93% increase in leaf yield and a 27.38% increase in yield value per unit area. …”

Data Sheet 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx by Manling Zhang (566460)

“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”

Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx by Manling Zhang (566460)

“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”

Image 2_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg by Shuting Hua (21264785)

“…The decline in disease burden was most pronounced in high-SDI regions, while low-SDI regions faced a significantly higher disease burden and exhibited notable regional disparities. …”

Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of... by Xiaoqing Xia (14607269)

“…</p>Results<p>The number of IHD deaths and DALYs resulting from non-optimal temperature experienced a rise of 71.6% and 60.6%, respectively. And it showed regional imbalances: in the region with low-middle socio-demographic index (SDI), it was increased [EAPC for ASMR: 0.39% (95% CI: 0.2%, 0.58%), EAPC for ASDR: 0.33% (95% CI: 0.15%, 0.52%)], while decreased in the high SDI region, [EAPC for ASMR: −3.44% (95%CI: −3.58%, −3.3%), EAPC for ASDR: −3.18% (95%CI: −3.32%, −3.03%)]. …”

Image 1_Tanyu Tongzhi Formula relieves the progression of atherosclerotic plaque through lipid regulation and anti-inflammatory effects.jpeg by Tingting Chen (111216)

“…Objective<p>Tanyu Tongzhi Formula (TTF), a clinically proven empirical prescription, has been utilized to treat atherosclerosis (AS) for decades. …”

Image 1_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg by Shuting Hua (21264785)

“…The decline in disease burden was most pronounced in high-SDI regions, while low-SDI regions faced a significantly higher disease burden and exhibited notable regional disparities. …”

Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 5_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”