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17741
Table 1_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.pdf
Published 2025“…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …”
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17742
Table 2_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx
Published 2025“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”
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17743
Image 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf
Published 2025“…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …”
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17744
Data Sheet 1_Effects of plant extracts on patients with heart failure: a network meta-analysis of randomized controlled trials.pdf
Published 2025“…Shenfu extract exhibited superior efficacy in decreasing B-type natriuretic peptide (BNP) values (SUCRA: 68.2%) and enhancing the quality of life (QL) (SUCRA: 77.0%). …”
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17745
Table 10_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.xls
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
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17746
General.Data. Proyect Glycerol.csv
Published 2025“…Additionally, although BT slightly decreased (<i>p</i> = 0.053, <i>d</i> = 0.37), it did not reach statistical significance, suggesting a trend toward lower body temperature, potentially reflecting enhanced thermoregulation.…”
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17747
Science Update: Precipitation and Snowfall in the Narragansett Bay Region
Published 2024“…Linear regressions were performed to test for significance. Only statistically significant regressions are included on the figures.…”
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17748
Table 5_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls
Published 2025“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”
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17749
Table 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease: a m...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
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17750
Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d...
Published 2024“…High-Performance Liquid Chromatography analysis revealed that while tartaric acid levels remained constant, malic acid content decreased, and acetic acid was produced by all strains. …”
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17751
Table 1_The interaction between temperature and rainfall determines the probability of tropical forest fire occurrence in Hainan Island.docx
Published 2025“…The results show that: (1) climatic factors contribute most significantly to the tropical forest fire probability, followed by human activities and topography, while vegetation factors (i.e., normalized difference vegetation index) made no significant contribution; (2) temperature and rainfall are the dominant factors influencing fire probability, with rising temperatures and decreasing rainfall substantially increasing the forest fire hazard; and (3) both logistic regression and random forest are reliable for predicting tropical forest fire hazards, but random forest demonstrates greater adaptability. …”
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17752
Table 1_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”
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17753
Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip
Published 2024“…Four of these factors were significantly causally related to the incidence of heart failure: CXCL9 and IFN-γ as promotive factors, and LIFR and UPA as potential protective factors. …”
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17754
Image 2_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg
Published 2025“…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”
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17755
Data_Sheet_1_Air pollutants and ovarian reserve: a systematic review of the evidence.PDF
Published 2024“…Background<p>Growing evidence indicates an association between ambient air pollution and decreased human reproductive potential. This study aims to systematically review the association between air pollutants and female ovarian reserve.…”
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17756
Image 3_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”
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17757
Image 4_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”
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17758
Data Sheet 1_Craving on the move: targeting smoking memories with a novel 3MDR–smoking cessation protocol.pdf
Published 2024“…Smoking cue–induced craving and physiological measures were assessed at baseline (T0) and 1 day after the intervention (T4), and smoking behavior was measured at T0 and 2-week (FU1) and 3-month (FU2) follow-up.</p>Results<p>Significant decreases in cue-induced craving from T0 to T4 and daily cigarette use from T0 to FU1 and FU2 were observed but not differ between the two experimental groups. …”
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17759
Table 1_The effect of omega-3 supplementation on metabolic, inflammatory and oxidative stress biomarkers in pregnant women: a systematic review and meta-analysis.docx
Published 2025“…However, triglyceride (SMD = −0.96, 95% CI: −1.77, −0.16) and CRP (SMD = −0.98, 95% CI: −1.86, −0.11) significantly decreased, and HDL-C cholesterol levels significantly increased (SMD = 0.72, 95% CI: 0.21, 1.22) following omega-3 supplementation.…”
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17760
Data Sheet 1_Increased risk of deep vein thrombosis, pulmonary embolism, and all-cause mortality in chronic venous disorder: a large-scale retrospective cohort study.docx
Published 2025“…Background<p>Chronic venous disorder (CVD), often overlooked as a significant medical burden, has recently been linked to severe health risks, especially deep vein thrombosis (DVT), and pulmonary embolism (PE). …”