Data Sheet 1_Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics.docx by Tao Jiang (28401)

“…Background<p>Diabetes mellitus (DM) is a metabolic disease with high morbidity, which significantly affects human life and health expenditures. …”

Table 1_Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis.xls by Jiangqin He (18852987)

“…Introduction<p>Osteoarthritis (OA) is a prevalent and debilitating disorder that affects the joints and has a complex array of causes. …”

Table 2_Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis.xls by Jiangqin He (18852987)

“…Introduction<p>Osteoarthritis (OA) is a prevalent and debilitating disorder that affects the joints and has a complex array of causes. …”

Data Sheet 2_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip by Yimin Zhou (3857113)

“…Animal experiments confirmed a significant decrease in the behavioral scores of rats in the SCI group, pathological changes in tissue sections, and differential expression of candidate genes in the SCI rat model.…”

Data Sheet 1_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip by Yimin Zhou (3857113)

“…Animal experiments confirmed a significant decrease in the behavioral scores of rats in the SCI group, pathological changes in tissue sections, and differential expression of candidate genes in the SCI rat model.…”

Data Sheet 1_HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia.zip by Joanne K. Agus (12889409)

“…HDL from 36-h fasted individuals were significantly more effective in effluxing cholesteryl esters from treated microglia, showing a remarkable 10-fold improvement compared to HDL from the postprandial state. …”

Data Sheet 1_Detection of hemodynamic changes in a porcine lipopolysaccharide model of systemic inflammation using dynamic light scattering measurements of the microcirculation.pdf by Louwrina H. te Nijenhuis (20762678)

“…Background<p>The microcirculation is affected during sepsis, yet there is currently no clinically available technology for sepsis detection in the microcirculation. …”

Table3_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table4_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table1_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table2_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table 1_Global, regional, and national burden of atrial fibrillation/flutter attributable to metabolic, behavioral, and environmental risk factors, 1990–2021: a longitudinal observ... by Zhen Wei (203204)

“…Smoking showed the greatest decrease, with AAPCs of ASMR and ASDR at −0.66 (95% CI: −0.68 to −0.65) and −0.72 (95% CI: −0.72 to −0.71), most significantly in women aged 30–34. …”

Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Routine blood tests revealed significantly elevated neutrophil granulocytes and monocytes, along with a marked decrease in lymphocytes. …”

Supplementary file 1_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Routine blood tests revealed significantly elevated neutrophil granulocytes and monocytes, along with a marked decrease in lymphocytes. …”

Image 1_Temporal trends and epidemiological impact of metabolic risk factors on stroke burden in Chinese individuals aged 65 and older, 1992–2021.tif by Haiying Wang (6869)

“…Background<p>Stroke remains a principal cause of mortality and disability globally, with approximately 75 percent of strokes affecting individuals aged 65 and older. High fasting plasma glucose (HFPG), high LDL cholesterol (LDL-C), and high systolic blood pressure (SBP) are significant metabolic risk factors contributing to the increasing stroke burden. …”

Data Sheet 1_Investigation of the anti-Huanglongbing effects using antimicrobial lipopeptide and phytohormone complex powder prepared from Bacillus amyloliquefaciens MG-2 fermentat... by Zhicheng Ding (18794422)

“…<p>Global citrus production has been severely affected by citrus Huanglongbing (HLB) disease, caused by Candidatus Liberibacter asiaticus (Clas), and the development of effective control methods are crucial. …”

Table1_Comprehensive transcriptome analysis of AP2/ERFs in Osmanthus fragrans reveals the role of OfERF017-mediated organic acid metabolism pathway in flower senescence.xlsx by Jing-Jing Zou (19743220)

“…Overexpression of OfERF017 leads to significant enrichment of genes in organic acid metabolism pathways, which leads to a decrease in organic acid levels and promoting the flower senescence of O. fragrans. …”

Improving QoL through the use of STAT-ON™. by Daniel Rodriguez-Martin (22411006)

“…<div><p>Parkinson’s Disease (PD) is a progressive neurodegenerative disorder affecting millions of patients worldwide, with significant economic and social implications. …”

Data Sheet 1_Factors influencing burnout, stress levels, and coping strategies among nursing staff in intensive care units.docx by Beata Wudarczyk (21409739)

“…Introduction<p>Professional burnout among nurses, particularly in intensive care units, is a significant issue affecting both healthcare professionals and patient care quality. …”

Table 1_Fibromyalgia diagnosis from a multi-omics approach: a gut feeling.pdf by Elena Durán-González (17438448)

“…After the raw data analysis, proteins with statistically significant differential abundance and a fold change over 1.2 (20% increase in fibromyalgia compared with control samples) or under 0.8 (20% decrease in fibromyalgia compared with control samples) in fibromyalgia were selected. …”