Table4_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Image_4_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Image 1_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”

Table 3_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.xl... by Junhyeok Choi (14078586)

“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”

Table_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.XLSX by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Table 1_The improvement effect of insoluble dietary fiber of Polygonatum sibiricum on hyperlipidemia in high-fat diet mice via gut microbiota and metabolites.docx by Yanli Ma (125469)

“…</p>Results<p>The results of the LIDF and HIDF showed that the PIDF treatment significantly alleviated the liver and kidney weight and body fat index. …”

Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Data Sheet 1_A comprehensive examination and analysis of the effectiveness and safety of finerenone for the treatment of diabetic kidney disease: a systematic review and meta-analy... by Jianyu Chen (2624254)

“…</p>Results<p>The analysis of 4 randomized controlled trials involving 13,943 participants found that finerenone treatment significantly decreased the urine albumin-to-creatinine ratio compared to placebo. …”

Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling by Ying Tao (469347)

“…We found that fasting could inhibit glycolysis and cell migration/invasion in GBC cells and that fasting mimic diets could significantly inhibit GBC cell proliferation in a mouse xenograft model. …”

Data Sheet 1_Effect of NR1D1 on the proliferation and differentiation of yak skeletal muscle satellite cells.pdf by Yuqi Zhe (20107152)

“…Compared with those in the control group, the expression levels of proliferation marker genes KI-67, CYCLIND1, and CYCLINA were significantly inhibited after NR1D1 overexpression, which was also supported by the CCK-8 test, whereas differentiation marker genes MYOD, MYOG, and MYF5 were significantly inhibited. …”

Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Table 2_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx by Kaihao Lin (13016658)

“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”

Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model by figshare admin karger (2628495)

“…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …”

Global maximum GPP from 2001-2018 by Xu (7493744)

“…The GPPmax estimates from this study and the changes in their trends were highly correlated with GPPmax estimates from the vegetation photosynthesis model, with R2 > 0.70 for most vegetation types. The GPPmax significantly increased in western North America, northern Europe, and eastern China, but decreased in tropical regions. …”

Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf by Rong Wu (152554)

“…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…”

Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx by Feilong Yang (1472296)

“…In FaDu HSCC cells, siRNA-mediated HDGF knockdown significantly attenuated proliferation, migration, and invasion. …”

Table 1_Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.docx by Tuanjie Wang (6619406)

“…</p>Conclusion<p>Although the global burden of diarrhea has decreased significantly, it is still high in low-income countries and low- and medium-SDI areas, and newborns are at high risk. …”

Table 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.xlsx by Melissa S. Monson (8281047)

“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”

Supplementary Material for: Comparing Two Oral Immunotherapy Strategies for Sesame Allergy: Baked Goods with Sesame Paste Versus Crushed Sesame Seeds by figshare admin karger (2628495)

“…For both the baked goods and the seeds group, likelihood of severe reactions significantly decreased over time. Conclusion: A modified sesame desensitization protocol using baked sesame paste can be safely used in children with sesame allergy.…”