Table 1_Mental symptoms in post-COVID syndrome and post-COVID-19 vaccination syndrome: results of a representative population survey.docx by Andreas Czaplicki (21978866)

“…</p>Results<p>The prevalence of self-reported mental symptoms of PCS was 12.1% among respondents, with women and younger individuals more commonly affected. The prevalence of self-reported PCVS was 12.6% among vaccinated individuals, with no significant gender differences, but fewer cognitive symptoms in older adults. …”

Data Sheet 1_A distal regulatory element regulates Wx gene expression and the amylose content in rice.pdf by Qingqing Yang (1628146)

“…However, no significant difference in amylose content was observed between wild-type plants and Wx^a-cre mutants which carried the Wx^a allele. …”

Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx by Na Zhu (331131)

“…In subgroup analyses, interaction tests showed that age, education, deprivation, obesity, smoking, hypertension, diabetes, and hyperlipidemia significantly affected the association between LC9 and MASLD (P for interaction < 0.05). …”

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx by Juanzhao Cao (22651742)

“…Population growth and epidemiological changes contributed significantly to the increase in the burden of OUD.</p>…”

Table 2_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx by Jiayue Zhang (7832669)

“…The APC model showed that the incidence increased significantly with the increase of age. Compared with China, the age of high incidence in Singapore, South Korea and Finland has moved forward. …”

Image_3_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.JPEG by Katrina S. Hofstetter (17545425)

“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”

Table 4_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx by Jiayue Zhang (7832669)

“…The APC model showed that the incidence increased significantly with the increase of age. Compared with China, the age of high incidence in Singapore, South Korea and Finland has moved forward. …”

Table 5_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx by Jiayue Zhang (7832669)

“…The APC model showed that the incidence increased significantly with the increase of age. Compared with China, the age of high incidence in Singapore, South Korea and Finland has moved forward. …”

Table 2_Epidemiological trends and disparities in iodine, vitamin A, and iron deficiencies among children aged 0–14 years globally, 1990–2021.docx by Fang Peng (327071)

“…Projections indicate sustained declines for iodine and vitamin A deficiencies but stagnation in iron deficiency, particularly in conflict-affected areas.</p>Conclusion<p>While iodine and vitamin A deficiencies have significantly reduced globally, dietary iron deficiency persists in low SDI regions. …”

Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif by Bojun Chen (317487)

“…</p>Conclusion<p>This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.…”

Data Sheet 1_Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microb... by Yunjiao Shen (20524133)

“…Fecal analysis revealed that TMG reconstructed the gut microbiota in colorectal cancer-affected mice by augmenting the abundance of the advantageous bacterium Lactobacillus and decreasing the abundance of the harmful bacterium Proteus.…”

S2 File - by Jinfeng Zhao (142391)

“…The roles of Klotho were further confirmed through knockdown of Klotho by small interfering RNA (siRNA) in C57BL/6J mice.Q-PCR and Western blot were performed to quantify determine the expression of relevant genes and proteins in the kidney. Results: Aging decreased Klotho expression via activated the upstream TGF-β1/p53/miR34a signaling pathway and affected its downstream signaling pathways, ultimately leading to renal fibrosis. …”

Data Sheet 1_Influence of water temperature on feed intake, appetite control, and energy allocation in Atlantic salmon (Salmo salar) post-smolt.pdf by F. Lai (17234491)

“…Plasma ghrelin (Ghrl) levels decreased significantly at elevated temperature. Temperature negatively affected the ghrl1 expression in the stomach, and the expression dynamics of the orexigenic neuropeptide npya and anorexigenic pomca paralogues in the hypothalamus, which were lower at 15°C. …”

Data Sheet 1_Spatiotemporal dynamics and influencing factors of native and invasive saltmarshes in a rapidly silting bay during 1985–2023.docx by Mingshan Xu (15370147)

“…Results showed that native saltmarshes significantly decreased from 632.24 ha to complete disappearance, while S. alterniflora expanded from zero to 2872.90 ha in Yueqing Bay during 1985-2023. …”

Table 1_Epidemiological trends and disparities in iodine, vitamin A, and iron deficiencies among children aged 0–14 years globally, 1990–2021.doc by Fang Peng (327071)

“…Projections indicate sustained declines for iodine and vitamin A deficiencies but stagnation in iron deficiency, particularly in conflict-affected areas.</p>Conclusion<p>While iodine and vitamin A deficiencies have significantly reduced globally, dietary iron deficiency persists in low SDI regions. …”

Image_2_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg by Katrina S. Hofstetter (17545425)

“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”

<b>The Mediating Role of Mental Fatigue Awareness in the Relationship Between Perceived Stress and Psychological Well-Being Among Combat Athletes</b> by coşkun yılmaz (21505391)

“…</b>Perceived stress significantly increased mental fatigue awareness (b = 0.732 ± 0.064, β = 0.549, p = 0.001) and directly decreased psychological well-being (b = –0.488 ± 0.166, β = –0.191, p = 0.004). …”

Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer.... by Francisco Alejandro Lagunas-Rangel (13849122)

“…Phosphoproteomic data showed a general reduction in kinase phosphorylation, although some kinases exhibited increased activity. Affected kinases were significantly enriched in cancer-associated pathways, including insulin signaling, EGF–EGFR signaling, PI3K/AKT signaling, and the PD-L1/PD-1 immune checkpoint axis. …”

Image_2_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg by Katrina S. Hofstetter (17545425)

“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”

Supplementary file 1_Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021.pdf by Li Yang (6520)

“…Chronic obstructive pulmonary disease, stroke, and ischemic heart disease are most significantly affected by the aging trend. Notably, the older adults population exhibited the most pronounced increase in HIV/AIDS-related DALYs, especially in the 70–74 years group (AAPC: 7.96, 95% CI 6.69, 9.24). …”