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significantly affected » significantly associated (Expand Search), significantly reduced (Expand Search), significant effect (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
affected decrease » affected areas (Expand Search), effects decreased (Expand Search)
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2681
Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx
Published 2025“…</p>Results<p>The SIMPLE cohort included 210 participants (91 patients with MPE and 119 patients with BPE), and the BUFF cohort included 235 participants (50 patients with MPE and 185 patients with BPE). Sex did not significantly affect the diagnostic accuracy of CEA. …”
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2682
Table 1_Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.docx
Published 2025“…Multivariate smooth splines analysis revealed a nonlinear relationship (P for nonlinearity < 0.05), with the curve slope decreasing as MAP exceeded 103.23 mmHg. Significant interaction effects between MAP and age or sex on IFG risk were also identified (P < 0.05).…”
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2683
Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx
Published 2025“…<p>Lavender (Lavandula angustifolia Mill.) is a valuable aromatic plant with significant commercial importance. However, cold stress–one of the primary abiotic factors impacting sugar metabolism–adversely affects its agricultural productivity in Northeast China. …”
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2684
<b>Canagliflozin-induced adaptive metabolism in bone</b>
Published 2025“…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”
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2685
SEAwise report on the impact of socioeconomic effects of fisheries management adapted according to input from review workshops
Published 2025“…For demersal fleets, variable prices caused significant income shifts, though operational effort was independent of price. …”
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2686
Table 1_Epicatechin gallate and its analogues interact with sortase A and β-lactamase to suppress Staphylococcus aureus virulence.docx
Published 2025“…Furthermore, ECG synergized with ampicillin (Amp), enhancing its bactericidal effects and inhibiting the formation of persisters. ECG did not affect the expression of sortase A or β-lactamase but significantly alleviated the cytotoxicity of S. aureus USA300. …”
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2687
Table1_Nutrient allocation patterns in different aboveground organs at different reproductive stages of four introduced Calligonum species in a common garden in northwestern China....
Published 2024“…The nutrient distribution patterns at different reproductive stages are of great significance for further understanding the ecological adaptation and survival strategies of plants.…”
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2688
Table 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx
Published 2025“…This study investigates how aerobic exercise affects cognitive impairments caused by AS in ApoE<sup>−/−</sup> mice. …”
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2689
Data Sheet 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx
Published 2025“…This study investigates how aerobic exercise affects cognitive impairments caused by AS in ApoE<sup>−/−</sup> mice. …”
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2690
Data Sheet 1_Altitudinal patterns of soil and microbial C:N:P stoichiometry in subtropical forests in Daming Mountain, South China.docx
Published 2025“…In contrast, microbial biomass C, N, and P stoichiometric ratios exhibited the opposite or non-significant relationships with these factors. Notably, AN, AP, and SWC were the dominant factors affecting soil microbial biomass C:N:P stoichiometry.…”
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2691
Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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2692
Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx
Published 2025“…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”
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2693
<b>Litter decomposition regulated by stand ECM dominance but not litter mycorrhizal type in a subtropical mountainous forest</b>
Published 2025“…</a> AM and ECM litter decomposition in plots with a natural gradient of ECM tree dominance showed that the decomposition rates of both AM litter and ECM litter decreased significantly in plots with increasing ECM dominance. …”
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2694
Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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2695
Table 5_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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2696
Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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2697
Table 2_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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2698
Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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2699
Multi-omics reveals glycolipid metabolism processes during the early development of largemouth bass (Micropterus salmoides)
Published 2025“…Early embryos' yolk and oil droplet diameters decreased significantly with embryonic development (P < 0.05). …”
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2700
Data Sheet 1_Impact of drought stress on biochemical and molecular responses in lavender (Lavandula angustifolia Mill.): effects on essential oil composition and antibacterial acti...
Published 2025“…<p>Drought stress significantly influences the physiological, biochemical, and molecular processes in plants, directly impacting their growth and defense mechanisms. …”