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significantly affected » significantly associated (Expand Search), significantly reduced (Expand Search), significant effect (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
affected decrease » affected areas (Expand Search), effects decreased (Expand Search)
significantly affected » significantly associated (Expand Search), significantly reduced (Expand Search), significant effect (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
affected decrease » affected areas (Expand Search), effects decreased (Expand Search)
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3021
Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx
Published 2025“…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …”
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3022
Model index comparison.
Published 2024“…The factors within the Park attributes (G1) and the park’s social media level (G4) showed a two-way interaction strength increase. (4)The coefficients of influence of impact factors on the space heterogeneity of vacation park vitality exhibit significant variation. The positive indicators have a spatial distribution that decreases from the northwest to the southeast, with the old city district having higher coefficients than the new city district. …”
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3023
'Plan-B': Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes
Published 2025“…One-third of respondents reported already experiencing significant impact from funding changes, while over two-thirds expressed high concerns about future effects. …”
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3024
Internal states adjust the Brp compartmental heterogeneity through octopamine.
Published 2025“…*<i>P</i> < 0.05 and ns = not significant. The data underlying this Figure can be found in S1 Data.…”
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3025
Validation of an abortive response with elevated NF-κB activity distinct from full lytic reactivation.
Published 2024“…(D) Frequencies of <i>CD38</i><sup>+</sup> and <i>BCL2A1</i><sup>+</sup> cells presented in 3C by treatment condition at 24 h and 48 h. Asterisks denote significantly decreased frequencies of <i>CD38</i><sup>+</sup> cells and increased frequencies of <i>BCL2A1</i><sup>+</sup> cells upon 4HT and 4HT+PAA treatment versus respective control treatments (n = 3 per condition; two-tailed Welch’s t-test; **p<0.01). …”
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3026
Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx
Published 2024“…The analysis revealed that 130 preferred terms (PTs) with significant disproportionality were based on the four algorithms, 67 (51.53%) of which were not included in the product labeling, affecting 6 systems and organs. …”
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3027
Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
Published 2025“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”
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3028
Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
Published 2025“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”
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3029
Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif
Published 2025“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”
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3030
Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
Published 2025“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”
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3031
Principal component analysis of soil parameters.
Published 2025“…The result showed that slope gradients, soil depths, and slope gradients interacting with soil depths had very highly, highly and significant effects on selected soil parameters, exchangeable bases, and extractable micronutrients. …”
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3032
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi...
Published 2025“…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I<sup>2</sup> = 23%) in patients with SGLT-2i treatment compared with non-users. …”
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3033
SEAwise synthesis of predicted impacts of changes in habitat and spatial management measures suggested in SEAwise for online tool
Published 2025“…</li></ul><p dir="ltr">The scenarios investigated in SEAwise suggest that prohibition of certain fishing practices, not only in currently designed MPAs but also in fit-to-purpose areas to limit the risk of incidental species and the degradation of benthic status, will significantly impact the overall fisheries economy and fish populations. …”
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3034
PDLB - Balance Sheet
Published 2024“…</p><p><br></p><p dir="ltr">On the expense side, there was significant concern into the 2023 results about non-interest expense. …”
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3035
Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing
Published 2025“…To understand how reindeer grazing, coupled with changes in snow depth affects CO<sub>2</sub> exchange, we used recent snow treatments (ambient, reduced, and increased snow depth) combined with 25- and 55-year-old reindeer exclusions and the adjacent grazed areas in boreal and subarctic Scots pine forests that are main winter pastures for reindeer/caribou and cover a significant portion of boreal and subarctic landscapes. …”
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3036
Table1_CD34 evaluation of microvasculature in lung adenocarcinoma and its microvascular density predicts postoperative tumor recurrence.xlsx
Published 2025“…Thus, the detection of intratumoral MVD is of great significance for understanding disease progression and predicting patient prognosis.…”
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3037
Adverse events in patients with castration-resistant prostate cancer treated with ra-223: a retrospective pharmacovigilance study
Published 2024“…These Ra-223-induced AEs were observed in 26 target system organ classes (SOCs). 124 Ra-223-induced AEs were detected in 26 SOCs, predominantly affecting the blood and lymphatic systems. Other notable AEs included diarrhea, nausea, asthenia, fatigue, malaise, and decreased appetite, some of which were not previously documented in product specifications. …”
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3038
Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025
Published 2025“…Transient IR episodes, like gestational diabetes or stress-induced hyperglycemia, also heighten the risk of later diabetes development. While the health significance of transient IR is well established, we aimed to better understand the heretofore poorly understood molecular processes that occur after such episodes.…”
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3039
Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development.
Published 2025“…</i> 25°C control) leads to increased aCC NMJ terminal size and decreased postsynaptic GluRIIA, while not affecting subunit GluRIIB expression. …”